• Molecular mechanisms of CD8+ T cell mediated control of HIV-1 infection in peripheral blood and lymphoid tissues. 

  Ogunshola, Funsho Japhet. (2019)

  Naturally induced CD8+ T cells do not clear human immunodeficiency virus (HIV) infection, partly because the virus rapidly escapes CD8+ T cell responses and the effector cells are excluded from HIV reservoirs sites. However, ...

• Insight into cancer targets and ligand binding landscape using bioinformatics and integrated molecular modeling tools. 

  Ndagi, Umar. (2017)

  The alarming rate of varying types of cancer diseases in human remains a global burden requiring drastic treatment in which, a prominent method of combating it is through enzymebased drug design. Metastatic castration-resistant ...

• Visual function and quality of life in adolescents with visual impairment: a case study of the Arthur Blaxall School in Pietermaritzburg. 

  Naipal, Shivani. (2018)

  Background: Visual impairment (VI) may affect the lives of children, adolescents and adults although the effects of VI on the former two groups may be taken for granted as they account for less than half the population ...

• Theoretical study on the esterification of methanol with acetic acid and acid halides. 

  Lawal, Monsurat Motunrayo. (2015)

  Esters are a unique class of organic compounds whose production and reactivity are examined in chemical industries and research laboratories throughout the world on a daily basis. An ongoing advancement in esterification ...

• Novel series of dehydrozingerone inspired potential antimycobacterial agents: design, synthesis, spectral studies and in vitro biological evaluation. 

  Hampannavar, Girish Appasaheb. (2016)

  Tuberculosis (TB) is a key health burden globally. With the emergence of resistance issue, the antitubercular research has been challenging. Novel effective drugs are immediately required to treat this serious epidemic ...

• Matching a chelator (DOTA) with ions for radio-pharmaceutical applications using DFT study. 

  Frimpong, Ebenezer Kwabena. (2016)

  Organometallic chelators can be potentially used for radiometal-based pharmaceuticals. The bifunctional chelator, which is covalently bound to a lead compound, forms a stable chelator―ion complex to deliver an isotope, as ...

• The impact of the introduction of generics and generic references pricing and candesartan and rosuvastatin utilisation, price and expenditure in South Africa. 

  De Jager, Hendrik Petrus. (2017)

  Rationale for the study The growth of pharmaceutical expenditure as a percentage of total health care expenditure has stagnated, both locally and globally, despite increasing consumption. Two factors that contributed ...

• Exploring trends in antibiotic use and resistance in a district, regional and tertiary hospital in the uMgungundlovu District. 

  Desai, Ayesha. (2017)

  Antibiotics play an important role in overcoming life-threatening bacterial infections. However, the increasing rate of antibiotic resistance is a serious threat to public health. Undoubtedly the indiscriminate use of ...

• Complexation strategies for the design of novel nano-drug delivery systems to treat bacterial infections caused by superbugs. 

  Hassan, Daniel. (2019)

  Abstract available in the PDF.

• Novel lipidic materials to enhance the transdermal delivery of tenofovir. 

  Rambharose, Sanjeev Kumar. (2017)

  The global burden of HIV and AIDS coupled with the limitations of current oral tenofovir (TNF) administration drives the need to develop strategies such as the use of alternate routes of administration to improve drug ...

• Trend analysis of antibiotic resistance in KwaZulu-Natal : a retrospective study 2011- 2015. 

  Patel, Miriam. (2017)

  Objective: Antimicrobial resistance is a global phenomenon which is limiting treatment options for common infections resulting in poor clinical outcomes, increased mortality and increased cost of healthcare. Antibiotic ...

• Experiences of Implanon NXT® users at public health facilities in South Africa. 

  Prosad, Shimona. (2018)

  Background and aim: Implanon NXT® was introduced in South Africa (SA) in the public health sector in February 2014. There exist concerns with premature Implanon NXT® user discontinuation in SA however, the true extent ...

• Comparison of adherence to treatment and effectiveness of fixed dose combination ARV drugs to multiple dose regimens in adult patients in public sector. 

  Jali-Lubanga, Helen Lulama. (2018)

  Background As antiretroviral medicines have become increasingly available and affordable for the treatment of HIV infected patients in South Africa, the adoption of a fixed dose combination (FDC) was implemented in 2013 ...

• Novel antimicrobial peptides for enhanced antimicrobial activity against methicillin resistant Staphylococcus aureus: design, synthesis and formulation. 

  Faya, Andile Kennedy Mbuso. (2018)

  Abstract available in pdf.

• The association between physical activity and body mass index, quality of life, life-space mobility and successful aging in older adults. 

  Naiker, Jacqueline. (2018)

  The biggest threat to healthy aging is sedentary living with the golden years of most individuals being affected by disorders that are exacerbated by unhealthy lifestyles. Helping people age better is important and it can ...

• An audiological and genetic profile of hearing of learners suspected of familial hearing loss attending schools for the deaf in KwaZulu-Natal. 

  Pillay, Karen. (2017)

  This study focused on genetic familial hearing loss, concentrating on learners attending schools for the Deaf in Kwazulu Natal .The study sought to identify the audiological profile characteristics of suspected genetic ...

• Impact of low vision on quality of life of patients with low vision visiting the low vision center of the Eastern Regional Hospital, Ghana. 

  Adamptey, Beatrice. (2017)

  Introduction: Low vision impacts quality of life and more so when the vision loss is severe. Persons living with low vision have reduced functionality and psychosocial well-being with the potential for high dependence on ...

• The oral hygiene status of people with dysphagia: a descriptive study. 

  Weimers, Merryl Justine. (2018)

  The aim of the study was to assess and describe the oral hygiene problems of adults admitted to a sub-acute rehabilitation hospital who presented with dysphagia. A descriptive, cross-sectional survey study design was ...

• Long distance running in Ethiopian athletes: a search for optimal altitude training. 

  Tola, Zeru Bekele. (2018)

  ABSTRACT Background The extended dominance of Ethiopian and Kenyan middle- and long- distance athletes in world athletics has resulted in researchers proposing numerous explanations to explain this success. Genetic ...

• Percutaneous endoscopic gastrostomy feeding decisions made by caregivers for children with cerebral palsy who experience feeding and swallowing difficulties in a public health care setting in Pietermaritzburg, South Africa: an exploratory study. 

  Naidoo, Lavanya. (2018)

  Abstract available in pdf.

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