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dc.creatorRiou, Catherine.
dc.creatorBurgers, Wendy A.
dc.creatorMlisana, Koleka.
dc.creatorRoederer, Mario.
dc.creatorAbdool Karim, Salim Safurdeen.
dc.creatorWilliamson, Carolyn.
dc.creatorGray, Clive M.
dc.creatorKoup, Richard A.
dc.date.accessioned2016-11-01T08:49:45Z
dc.date.available2016-11-01T08:49:45Z
dc.date.created2014
dc.date.issued2014
dc.identifier.citationRiou, C., Burgers, W.A., Mlisana, K., Koup, R.A., Roederer, M., Karim, S.S.A., Williamson, C. and Gray, C.M. 2014. Differential impact of magnitude, polyfunctional capacity, and specificity of HIV-specific CD8+ T cell responses on HIV set point. Journal of virology 88(3), 1819-1824.en_US
dc.identifier.urihttp://dx.doi.org/10.1128/JVI.02968-13en_US
dc.identifier.urihttp://hdl.handle.net/10413/13554
dc.descriptionCAPRISA, 2014.en_US
dc.description.abstractDefining the characteristics of HIV-specific CD8(+) T cell responses that lead to viral control is crucial for vaccine development. We evaluated the differential impact of magnitude, polyfunctional capacity, and specificity of the CD8(+) response at approximately 6 months postinfection on the viral set point at 12 months in a cohort of HIV-infected individuals. High frequencies of Gag and Nef responses endowed with four functions were the best predictors of a low viral set point.en_US
dc.language.isoenen_US
dc.publisherAmerican Society for Microbiology.en_US
dc.subjectHIV Infections/immunology.en_US
dc.subjectHIV-1/genetics.en_US
dc.subjectCohort Studies.en_US
dc.titleDifferential impact of magnitude, polyfunctional capacity, and specificity of HIV-specific CD8+ T cell responses on HIV set point.en_US
dc.typePeer reviewed journal articleen_US


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