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Browsing by Author "Hecht, Frederick M."

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    Epigenetic mechanisms, T-cell activation, and CCR5 genetics interact to regulate T-cell expression of CCR5, the major HIV-1 coreceptor.
    (United States National Academy of Sciences., 2015) Gornalusse, German G.; Mummidi, Srinivas.; Gaitan, Alvaro A.; Jimenez, Fabio.; Ramsuran, Veron.; Picton, Anabela.; Rogers, Kristen.; Manoharan, Muthu Saravanan.; Avadhanam, Nymisha.; Murthy, Krishna K.; Martinez, Hernan.; Murillo, Angela Molano.; Chykarenko, Zoya A.; Hutt, Richard.; Daskalakis, Demetre.; Shostakovich-Koretskaya, Ludmila.; Abdool Karim, Salim Safurdeen.; Martin, Jeffrey N.; Deeks, Steven G.; Hecht, Frederick M.; Sinclair, Elizabeth.; Clark, Robert A.; Okulicz, Jason.; Valentine, Fred T.; Martinson, Neil.; Tiemessen, Caroline Tanya.; Ndung'u, Peter Thumbi.; Hunt, Peter W.; He, Weijing.; Ahuja, Sunil K.
    Abstract available in pdf.
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    HIV-Selectest enzyme immunoassay and rapid test: ability to detect seroconversion following HIV-1 infection.
    (American Society for Microbiology., 2009) Khurana, Surender.; Norris, Philip J.; Busch, Michael P.; Haynes, Barton F.; Park, Susan.; Sasono, Pretty.; Mlisana, Koleka Patience.; Abdool Karim, Salim Safurdeen.; Hecht, Frederick M.; Mulenga, Joseph.; Chomba, Elwyn.; Hunter, Eric.; Allen, Susan.; Nemo, George.; Rodriguez-Chavez, Isaac R.; Women’s Interagency HIV Study Collaborative Study Group.; Margolick, Joseph B.; Golding, Hana.
    HIV-Selectest is a serodiagnostic enzyme immunoassay (EIA), containing p6 and gp41 peptides, designed to differentiate between vaccine-induced antibodies and true infections. A rapid test version of the HIV-Selectest was developed. Both assays detected HIV antibodies in men and women within 2 to 4 weeks of infection, with sensitivity similar to third-generation EIAs.