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Antibody light-chain-restricted recognition of the site of immune pressure in the RV144 HIV-1 vaccine trial is phylogenetically conserved.

Abstract

Abstract available in pdf.

Description

CAPRISA, 2014.

Keywords

AIDS Vaccines., Amino Acid Sequence., Animals., Antibodies, Viral/metabolism., Antibody Affinity/genetics., B-Lymphocytes/immunology.

Citation

Wiehe, K., Easterhoff, D., Luo, K., Nicely, N.I., Bradley, T., Jaeger, F.H., Dennison, S.M., Zhang, R., Lloyd, K.E., Stolarchuk, C.,Parks, R., Sutherland, L.L., Scearce, R.M., Morris, L., Kaewkungwal, J., Nitayaphan, S., Pitisuttithum, P., Rerks-Ngarm, S., Sinangil, F., Phogat, S., Michael, N.L., Kim, J.H., Kelsoe, G., Montefiori, D.C., Tomaras, G.D., Bonsignori, M., Santra, S., Kepler, T.B., Alam, S.M., Moody, M.A., Liao, H.X., and Haynes, B.F. 2014. Antibody light-chain-restricted recognition of the site of immune pressure in the RV144 HIV-1 vaccine trial is phylogenetically conserved. Immunity 41(6), 909-918.

DOI