Masters Degrees (Medical Microbiology)
Recent Submissions
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Molecular surveillance of Staphylococcus aureus on frequently touched sites in public hospitals in KwaZulu-Natal, South Africa.
(2021)There is an escalation in the prevalence of hospital-acquired infections (HAI) due to the transfer of pathogens, such as methicillin-resistant Staphylococcus aureus (MRSA), within the hospital environment. Pathogens ... -
Distribution, virulence and antimicrobial resistance profile of Bacillus species from the environment of four public hospitals in South Africa.
(2021)Hospital-acquired infections (HAIs) are counted as the most crucial global health crisis. The hospital environment may be colonized by opportunistic pathogens, which can lead to HAIs in hospitalized patients. As a result, ... -
Characterization of immunoglobulin (Ig) isotypes, IgG subclasses and cytokines in the blood and genital tracts of HIV infected and healthy women from an observational cohort study (CAPRISA 082)
(2020)Background: Heterosexual transmission remains the dominant route of HIV infections in women. Immune responses that predict HIV acquisition during pre-exposure prophylaxis (PrEP) remain undefined. We hypothesized that ... -
Molecular epidemiology of antibiotic resistant Campylobacter spp. from farm-to-fork in an intensive pig production system in Kwazulu-Natal, South Africa.
(2021)Background: Campylobacter spp. are among the leading foodborne pathogens, causing Campylobacteriosis, a zoonotic infection that results in bacterial gastroenteritis and diarrhea disease in animals and humans. The emergence ... -
Molecular characterization of antibiotic-resistant Staphylococcus aureus in an intensive pig production system in KwaZulu-Natal, South Africa.
(2021)The increase in antibiotic resistance in food animals and food of animal origin has been attributed to the extensive use of antibiotics during animal husbandry giving rise to multidrug-resistant bacteria. Staphylococcus ... -
Prevalence and molecular susceptibility of Mycoplasma genitalium in KwaZulu-Natal population.
(2021)Background: Mycoplasma genitalium is a recently classified sexually transmitted pathogen associated with causing urethritis and cervicitis, potentially causing reproductive complications. Mycoplasma genitalium has been ... -
Induction of secondary metabolite production in endophytic fungi isolated from Albizia adianthifolia using multiple small compounds involved in fungal chromatin remodeling.
(2021)Fungi are an inexhaustible source of unexplored bioactive secondary metabolites that have been useful to humans as pharmaceuticals and other valuable products. The unexplored arsenal of secondary metabolites from fungi ... -
Investigating the prevalence of vaginitis pathogens in HIV infected and uninfected pregnant women In Durban, South Africa.
(2020)BACKGROUND: Vaginitis in pregnancy significantly contributes to obstetric complications such as preterm labor. Human Immunodeficiency Virus (HIV) infection is thought to increase risk of acquiring vaginitis in pregnancy ... -
Global transcriptome analysis of THP-1 cells infected with an rpfB gene knockout strain of Mycobacterium tuberculosis.
(2021)Background: Since the initial isolation of Mycobacterium tuberculosis (Mtb), tuberculosis (TB) remains among the top 10 causes of death. In 2019, 10 million people globally were burdened with TB, of which 25 %were from ... -
Molecular epidemiology of antibiotic resistant Escherichia coli from intensively-produced poultry in a farm-to-fork continuum in KwaZulu-Natal, South Africa.
(2020)The increased use of antibiotics in intensively produced food animals has resulted in the selection of drug-resistant bacteria across the farm-to-fork continuum. There is a risk of transfer of this resistance to humans ... -
Molecular surveillance and dissemination of Klebsiella pneumoniae on frequently encountered surfaces in South African public hospitals.
(2021)Hospital equipment and surfaces can harbour Klebsiella pneumoniae. In the absence of effective cleaning, anyone who encounters these surfaces can unknowingly spread this opportunistic pathogen throughout the hospital. This ... -
Spectrum of organisms and outcome of neonatal infections in HIV-exposed and unexposed newborns at a tertiary care hospital in KwaZulu-Natal.
(2021)The World Health Organisation’s (WHO) recommendation of life-long antiretroviral prophylaxis to pregnant women who are positive for Human Immunodeficiency Virus (HIV) has increased HIV-exposed but uninfected infants. ... -
Socio-cultural and behavioral factors affecting adherence to Tuberculosis treatment in Malawi.
(2021)Background: Non-adherence to TB treatment poses a major challenge to Tuberculosis (TB) control programs because it increases the risk of treatment failure, relapse and the emergence of drug resistant tuberculosis. Aim: ... -
Fumonisin B1 increases the NAD-dependant deacetylase SIRT1 to disrupt cholesterol flux in galactose supplemented HepG2 cells.
(2020)The Fusarium species are major fungal contaminants of maize, that produce an extremely toxic mycotoxin called Fumonisin B1 (FB1). Fumonisin B1 is a known causative agent of animal-related mycotoxicosis and is implicated ... -
Aspects of sexually transmitted diseases at King Edward VIII hospital.
(1988)Abstract available in PDF. -
Seroprevalence of Hepatitis B virus infection in a household-based representative sample of African men and women in KwaZulu-Natal, South Africa.
(2018)Background: In South Africa, hepatitis B virus (HBV) infection remains a major cause of morbidity and mortality, however, little is known about the prevalence and distribution of HBV in some regions and populations. Methods: ... -
Molecular epidemiology of antibiotic-resistant enterococcus spp. from farm to food-production chain in intensive poultry production in KwaZulu-Natal, South Africa.
(2019)Extensive antibiotic use in intensively-farmed poultry exerts selection pressure for the emergence of multidrug-resistant pathogens. The aim of this study was to determine the antibiotic resistance and virulence profiles ...
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