• A 10-year institutional review of surgery for structural valve dysfunction in the developing world. 

  Chih-Yuan, Chen. (2017)

  Background Prosthetic heart valves do not fulfil the requirements for an ideal valve, resulting in the development of prosthetic dysfunction or complications over time. Structural valve dysfunction may be influenced by ...

• An audit of the infection prevention and control program at Port Shepstone Regional Hospital. 

  Chetty, Sivathasen Kasaven. (2019)

  BACKGROUND Infectious diseases are the leading cause of death in South Africa. The treatment of these diseases and their complications consume huge amounts of already limited healthcare resources. Antibiotic resistance ...

• Increase in live infected cell number with drug and generation of a quasispecies are consequences of multiply HIV infected cells. 

  Jackson, Laurelle. (2018)

  HIV may form reservoirs in anatomical compartments and evolve a quasispecies in order to survive under selective pressures such as antiretroviral drugs. Lymph nodes and lymphoid tissue - critical sites for reservoir ...

• Size does not matter: a molecular insight into the biological activity of chemical fragments utilizing computational approaches. 

  Munsamy, Geraldene. (2016)

  Insight into the functional and physiological state of a drug target is of essential importance in the drug discovery process, with the lack of emerging (3D) drug targets we propose the integration of homology modeling ...

• The epidemiology and impact of pretreatment HIV drug resistance in adults in South Africa. 

  Chimukangara, Benjamin. (2018)

  HIV drug resistance (HIVDR) present prior to initiating or re-initiating antiretroviral therapy (ART), is known as pretreatment drug resistance (PDR). Conventionally, PDR is detected by Sanger sequencing. Drug resistant ...

• Faecal carriage of extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella spp. in Mozambican students. 

  Chirindze, Lourenço Marcos Junior. (2017)

  In recent years, the world has seen a surge in extended-spectrum β-lactamase (ESBL)-producing bacteria. Among antibiotic resistance mechanisms, the production of β-lactamase is the most rapidly developing and clinically ...

• PreNatal nicotine exposure and maternal separation alter the nicotinic acetylcholine receptors in mice. 

  Khan, Muhamed Waseem. (2019)

  Maternal cigarette smoking during pregnancy has been associated with long term cognitive dysfunction. The harmful behavioural effects of cigarette smoking have been shown to be primarily due to nicotine. While the mechanism ...

• The role of follistatin and granulocyte-colony stimulating factor in HIV-associated pre-eclampsia. 

  Mdlalose, Siphesihle. (2018)

  KZN has a high burden of HIV infection and high blood pressure, specifically pre-eclampsia (PE) in pregnancy. Follistatin (FS) and granulocyte-colony stimulating factor (G-CSF) are two glycoproteins involved in PE pathogenesis. ...

• A novel study to detect and quantify microorganisms associated with bacterial vaginosis from urine samples. 

  Naicker, Deshanta (2019)

  Bacterial vaginosis (BV) is the most common vaginal condition found in women of reproductive age. The lack of published data on the detection of BV-associated pathogens from urine, a non-invasive sample, lends novelty to ...

• An assessment of tne successes and shortfalls of the national birth defects databases and an improved data collection method of the databases. 

  Mtyongwe, Vuyiswa (2018)

  The Constitution of South Africa (SA) together with the National Health Act (63 of 1977) govern the provision of health services to the residents of the country. With a three-tier system of governance consisting of national, ...

• Transforming growth factor βeta 1-3 in HIV associated pre-eclampsia. 

  Mtshali, Zamahlabangane Sisiziwe. (2017)

  Introduction: Pre-eclampsia is a clinical syndrome that complicates approximately 3-8% of all pregnancies and is the second leading cause of maternal mortality. The maternal imbalance of pro-angiogenic and anti-angiogenic ...

• Deliberate self-harm at RK Khan hospital internal medicine department: the influence of age on the likelihood of admission, triggers, methods used and outcomes. 

  Brown, Susan Lynn. (2018)

  A prior suicide attempt is the most important risk factor for complete suicide. For every completed suicide it is estimated that more than 20 suicide attempts are made. From July to December 2016, Deliberate Self-Harm ...

• A standardised approach to the treatment and management of significant acinetobacter species infection at academic complex hospitals in KwaZulu-Natal. 

  Swe Swe-Han, Khine. (2017)

  Introduction: Carbapenem-resistant Acinetobacter species (Acinetobacter spp.) are increasingly recognised as important pathogens, whose resistance patterns present a high-risk global challenge. However, there is limited ...

• The clinical manifestations and response to treatment in South Africans with Lupus nephritis. 

  Mody, Priyesh G. (2016)

  Systemic lupus erythematosus (SLE) is an uncommon disease which is being recognised with increasing frequency in Africa, including South Africa. It is most common in young women and is associated with a significant morbidity ...

• A retrospective review of the clinical outcomes in patients admitted to a newly established medical High Care Unit at King Edward VIII Hospital. 

  Naidoo, Darrin Ryan. (2016)

  Abstract available in PDF file.

• A description of the profile of the patients and outcomes of fiber-optic bronchoscopies, performed at a tertiary care hospital in KwaZulu-Natal, South Africa, from January to December 2011. 

  Ramkillawan, Yeishna. (2014)

  Background Tuberculosis (TB), pneumonia and human immunodeficiency virus (HIV) were the three leading causes of natural deaths in South Africa in 2013 and 11.9% of all deaths in KwaZulu Natal were attributed to TB. In ...

• Renal manifestations of human immunodeficiency virus in the era of antiretroviral treatment in South Africa. 

  Assaram, Shirelle. (2016)

  Background: Sub-Saharan Africa carries the global burden of human immunodeficiency virus (HIV) infection. Renal disease is a well-recognized and closely associated complication of HIV infection. The burden of kidney disease ...

• Evolution of the CD4 count in the first 12 months following initiation of antiretroviral therapy in a South African public-sector patient population. 

  Mathenjwa, Mfundo Falethu. (2017)

  Abstract not available.

• A retrospective review of the demographic profile, disease activity, co-existent co-morbid disease and treatment in established rheumatoid arthritis at a tertiary center clinic. 

  Singh, Akira. (2016)

  Rheumatoid arthritis (RA) is one of the most common forms of chronic inflammatory arthritis and often results in joint damage, physical disability and premature mortality. The incidence of RA is increasing in developing ...

• Warfarin : time in therapeutic range, a single centre study on patients using warfarin for stroke prevention in non-valvular atrial fibrillation and prosthetic heart valves. 

  Sadhabiriss, Dhiren. (2016)

  Background: There are various indications for the use of oral anticoagulants. Two common indications are in patients with atrial fibrillation and prosthetic heart valves. The quality of anticoagulation, determined by the ...

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