Masters Degrees (Biochemistry)
Recent Submissions
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Silver nanoparticles from biological extracts and their antimicrobial activities.
(2017)The increasing incidence of multi-drug resistant organisms has led to the resurgence in application of Ag-based compounds. Accordingly, increased efforts have been made in the field of nanotechnology to develop silver ... -
Identification of infectious bursal disease virus (IBDV) receptors through the use of recombinant capsid protein, VP2.
(2014)Infectious bursal disease virus (IBDV) is a non-enveloped Birnavirus which infects the immature antibody producing B-cells of the bursa of Fabricius in young chickens. The virus causes infectious bursal disease (IBD) which ... -
Antidiabetic activity of Warburgia salutaris (Bertol. f.) Chiov. (Canellaceae).
(2017)Abstract available in PDF file. -
A novel in vitro anticancer drug delivery strategy using platinum encapsulated gold nanoparticles.
(2017)Abstract available in PDF file. -
Recombinant expression and bioinformatic analysis of plasmodium falciparum lactate dehydrogenase and heat shock protein 70-1.
(2017)Malaria remains a serious human health problem and the disease is particularly prevalent in developing countries. Malaria is caused by a parasite of the genus Plasmodium. Diagnosis of malaria is required before any treatment ... -
The application of layered double hydroxide nanoparticles (LDHs) as potential anticancer drug delivery systems.
(2016)Chemotherapy being one of the principle techniques used in cancer treatment, has been applied in the treatment of a wide spectrum of cancers. However, this mode of treatment is fraught with a myriad of challenges, reducing ... -
Delivery of Fluc-mRNA using functionalised gold nanoparticles in vitro.
(2016)Nanomedicine, a branch of nanotechnology which includes the use of nanoparticles, is set to revolutionize the area of gene therapy. Gold nanoparticles (AuNPs) have steadily gained favour as promising gene and drug delivery ... -
Effects of oleanolic acid and Centella asiatica on enzymes of carbohydrate metabolism in muscle and skin of streptozotocin-induced diabetic Sprague-Dawley rats.
(2016)Diabetes prevalence increases yearly with an expected increase to 642 million people by the year 2040. Conventional treatment of diabetes involves insulin therapy and other synthetic drugs. However, drawbacks of these forms ... -
An in vitro assessment of functionalized gold nanoparticles in anticancer drug delivery.
(2017)Abstract available in PDF file. -
Bio-guided isolation of biologically active compounds from seeds of selected South African medicinal plants.
(2016)Abstract available in PDF file. -
Trypanosoma congolense invariant surface glycoprotein: a potential diagnostic antigen for animal African trypanosomiasis.
(2016)Abstract available in PDF file. -
Effects of catharanthus roseus and centella asiatica leaf extracts on enzymes of glutamine catabolism in human colon carcinoma (CACO-2) cell line and in enterocytes from male sprague-dawley rats.
(2015)Phosphate-dependent glutaminase (PDG) is a key enzyme in several physiological processes and hence has become a target of anti-cancer drug development because of the role of glutamine in providing energy for rapidly dividing ... -
Over-expression of FLO11 encoded mannoprotein in Saccharomyces cerevisiae.
(2015)Abstract available in PDF file. -
Investigation into the major surface proteases of African trypanosomes.
(2016)The unicellular parasite of the genus Trypanosoma infects a number of mammalian species including livestock and humans. In sub-Saharan Africa three main parasitic species cause disease: Trypanosoma brucei, T. congolense ... -
Prevalence of molecular markers associated with chloroquine, sulphadoxine-pyrimethamine and lumefantrine resistance following the deployment of artemether-lumefantrine as first-line treatment for uncomplicated falciparum malaria in Gaza Province, Mozambique.
Antimalarial drug resistance is a major contributing factor to the sustained malaria burden in sub-Saharan Africa. Under extreme drug pressure, drug resistant parasites have a selective fitness advantage over wild-type ... -
Studies on the possible mechanisms behind the anti-diabetic effects of Xylitol.
(2013)Background and Objectives: Sugar substitutes have gained popularity in the management of diabetes, obesity and related diseases, due to their low calorie content compared to sucrose. Recent studies have reported that ... -
Effects of host sex and pregnancy on Trichinella Zimbabwensis infection in Sprague-Dawley rats and Balb C mice.
(2015-10-16)Trichinellosis is a zoonotic parasitic disease caused by nematode parasites of the genus Trichinella. Trichinella species infect a wide range of hosts including humans, domestic and wild animals. The main mode of human ... -
Yeast encapsulation for bioethanol production.
(2015-10-16)The bioethanol production industry is faced with hurdles such as uncovering cheap and abundantly available fermentation substrates, as well as yeast strains possessing high ethanol tolerance properties. Cane molasses is a ... -
Location and partial purification of phosphate dependent glutaminase from rat small intestine.
(2014)Phosphate dependent glutaminase (PDG) is a key enzyme in intestinal energy metabolism and hence has an impact on nutrient absorption and nutritional status of the whole animal. PDG is known to be a mitochondrial enzyme but ...
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