Biotechnology
Recent Submissions
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Diversity of quorum sensing pherotypes amongst ecotypes of plant-associated Bacillus subtilis sensu lato isolates.
(2021)Ecologically-adapted populations, or ecotypes, are species forms that are functionally adapted to particular habitat niches. Bacterial ecotypes are challenging the significance and implications of ecological adaptation ... -
Design, implementation and assessment of a novel bioreactor for dark fermentative biohydrogen production.
(2020)The majority of the world’s energy consumption and electricity generation is derived from fossil fuel sources. Their consumption has a negative environmental impact, thus the need for renewable energies. Hydrogen being ... -
Genetic diversity of some Moringa oleifera Lam. cultivars available in South Africa.
(2020)Moringa oleifera Lam. (Moringaceae) is a nutritious and high medicinal value tree. The species is native to India but grown globally due to its properties. The nutritional content of the species includes high levels of ... -
DNA metabarcoding of zooplankton enhances community-level analyses of connectivity in a marine pelagic environment.
(2021)Zooplankton are abundant and diverse marine organisms that form ecologically important communities in marine pelagic ecosystems. They are well-suited for biomonitoring of ecosystem health and changes in biodiversity ... -
The development and use of in vitro and in silico beta-site amyloid precursor protein cleaving enzyme-1 protein-ligand binding assays.
(2020)Abstract available in PDF. -
Identification and analysis of Cryptosporidium Glutathione Transferase.
(2021)Cryptosporidiosis, caused by Cryptosporidium spp. is a gastrointestinal disease which gives rise to severe life threatening complications in immunecompromised patients. The disease causing parasite has a proficient defense ... -
Production of lipopeptide biosurfactant by Paenibacillus sp. D9: basic and applied aspects.
(2019)Abstract available in PDF. -
Isolation and characterization of diaryl ester catabolizing soil fungi.
(2019)Aromatic hydrocarbons are major organic pollutants that can persist in the environment. However, many fungi and yeasts can utilize these compounds as carbon and energy sources under aerobic conditions. Salol and benzyl ... -
Process development for biomass and lipid production from a local chlorella isolate using a miniature parallel raceway pond reactor.
(2020)Abstract available in pdf. -
The glutaredoxin/glutathione post-stress recovery system is dependent on the availability of glutathione in the cell.
(2020)The cellular response to oxidative stress involves three interconnected processes: reactive oxygen species detoxification, adaptation and repair. Glutathionylation is an adaptive response in which glutathione binds to ... -
Recombinant cathepsin L-like cysteine proteases for species-specific diagnosis of animal African trypanosomiasis.
(2019)African trypanosomiasis is a disease caused by protozoan parasites i.e. Trypanosoma spp. in livestock and humans and affects 37 sub-Saharan countries. Animal African trypanosomiasis (AAT) is known as nagana and African ... -
Molecular cloning, recombinant expression and characterisation of serine and cysteine protease inhibitors from Trichinella zimbabwensis.
(2019)Trichinellosis is a disease caused by parasitic helminths of the genus Trichinella. Infection occurs by ingestion of meat contaminated with infective Trichinella larvae. Cases of Trichinella zimbabwensis, a non-encapsulating ... -
Molecula characterization of chlamdia trachomatis isolates using sequence variation in the major outer membrane protein gene (OMP1) and evaluation of their susceptibility profile.
(2019)Chlamydia trachomatis infections are the most common bacterial sexually transmitted infections (STIs) in humans, worldwide. Due to asymptomatic nature of C. trachomatis, the need for sensitive, reliable and affordable ... -
The stabilisation of the cysteine protease of Carica papaya (papain) and the catalytic domain of the Cathepsin L-like cysteine protease of Trypanosoma congolense (TcoCATL)
(2019)Proteases play an intricate role in the numerous functions of a living organism. Proteases are responsible for the cleavage of proteins into smaller fragments by catalysing the hydrolysis of peptide bonds. The class of ... -
Investigation of multiple concurrent Human papillomavirus infections, oncogenicity, and STI co-infection as risk factors for Human immunodeficiency virus infection.
(2017)Background: Human papillomavirus (HPV) is one of the most common sexually transmitted infections (STIs) globally and a necessary factor for cervical cancer development. While HPV infection has been associated with increased ... -
Transferrin receptor-mediated gene delivery using functionalised gold nanoparticles.
(2018)Gene therapy strategies have shown their potential in treating numerous central nervous system (CNS) disorders, including highly aggressive brain cancers. Gold nanoparticles (AuNPs) are popular vectors for gene delivery, ... -
Synthesis, detection and quantification of inulooligosaccharides and fructooligosaccharides by extracellular and intracellular inulinase and fructosyltransferase enzymes isolated from coprophilous fungi.
(2018)Exploration of fungal biodiversity capable of producing fructosyltransferase and inulinase enzymes in significant amounts is crucial for the production of oligofructans. Indigenous coprophilous fungi are predominantly ...
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