Masters Degrees (Pharmaceutical Sciences)
Recent Submissions
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Assessment of factors affecting adherence to chronic medicines among stable patients registered onto the Centralized Chronic Medicines Dispensing and Distribution (CCMDD) programme: the case of eThekwini Metropolitan Health District, South Africa.
(2018)Abstract Background Globally more deaths are due to chronic disease compared to infectious disease. In South Africa, the number of patients has been increasing over the years for those who have been diagnosed with ... -
Evaluating the impact of Single Exit Pricing (SEP) on medicine product withdrawal from the private health care market in South Africa.
(2019)ABSTRACT / SUMMARY Introduction The introduction of medicine pricing policies in South Africa in the form of Single Exit Pricing (SEP), provided a mechanism to improve medicine price transparency and reduce both medicine ... -
Direct treatment costs of invasive candidiasis in Haematology patients at a South African private hospital.
(2019)ABSTRACT Background: Haematology patients are at a high risk of developing invasive candidiasis (IC). Fluconazole has been the mainstay of prophylaxis and treatment but recently a newer class of therapeutic options, the ... -
Comparative chemistry of COA® herbal medicine and herbal extracts of azadirachta indica and carica papaya.
(2019)Natural products have indeed endowed man with a variety of efficacious benefit combinations which can be dated to origin of the universe. The essence of herbs in the mitigation of human indisposition cannot be overstressed. ... -
Cytochrome p450 monooxygenase cyp139 family involved in the synthesis of secondary metabolites in mycobacterial species.
(2019)Tuberculosis (TB) is one of the top infectious diseases causing numerous human deaths in the world. Despite enormous efforts, the physiology of the causative agent, Mycobacterium tuberculosis, is still poorly understood. ... -
Prescription pattern monitoring of outpatient pediatric patients.
(2019)Prescribing for paediatric patients can be challenging for prescribers as children are especially vulnerable to harmful effects of drugs due to differences in pharmacokinetics and pharmacodynamics as well as the limited ... -
Cost-analysis of Misoprostol and Mifepristone versus Misoprostol and Methotrexate when used for medical termination of pregnancy in women of gestational age of 7 weeks and less at Embhuleni Hospital in Elukwatini, Mpumalanga.
(2019)Background: The purpose of the Republic of South Africa Choice on Termination of Pregnancy Act 92 of 1996 is to provide a safe and effective alternative to the rife illegal abortions taking place in South Africa. ... -
Knowledge, attitudes and practices of veterinarians on antibiotic use, resistance and its containment in South Africa.
(2021)The inappropriate use of antibiotics in the veterinary sector has led to antibiotic resistance (ABR), which negatively impacts animal health and welfare and indirectly on human health. Understanding the knowledge, ... -
Awareness, attitudes, and experiences of patients taking antiretrovirals towards adverse drug reactions at a public health facility in KwaZulu-Natal.
(2020)Adverse drug reactions (ADRs) are undesirable side effects that occur even when a drug is administered at the proper dose and correctly for an appropriate indication. Given the high prevalence of Human Immuno-deficiency ... -
Development of a tool to assess knowledge, awareness and perception of prostate cancer amongst women in Ghana.
(2020)Background and Objectives: The incidence of prostate cancer in developing countries is less than 30%, yet it has the disease's highest mortality. To address the mortality, strategies to increase awareness of the disease ... -
Retail pharmacy prescription medicines availability, prices, and affordability in Eswatini.
(2021)Background: The low availability of medicines in public health outlets coupled with unaffordable prices in the private sector can be a major barrier to medicines’ access. Patients in Eswatini may be forced to buy medicines ... -
Functional and molecular changes associated with intranasal buprenorphine in a healthy rodent model.
(2020)Opioid addiction is a spiralling global epidemic associated with intense drug craving and the compulsive use of opiate drugs such as heroin, oxycodone, oxymorphone amongst others. Buprenorphine (BUP), commercially available ... -
Molecular epidemiology of antibiotic-resistant Enterococcus spp. from farm-to-fork in intensive pig production in KwaZulu-Natal, South Africa.
(2021)Background: Substantial antibiotic use and high population densities in intensive farming systems results in the emergence and spread of antibiotic-resistant commensals and pathogens. This study investigated the molecular ... -
Molecular epidemiology of carbapenem-resistant Enterobacterales colonization in an intensive care unit.
(2021)Background: Due to the high association with mortality and morbidity, carbapenem-resistant Enterobacterales (CRE) in general, and carbapenem-resistant Klebsiella pneumoniae, in particular, have been listed as high-priority ... -
The effects of naringenin on oxidative stress parameters in cardiac muscles of diabetic rats.
(2019)Introduction: Diabetic cardiomyopathy (DCM) is defined by hypertrophy, oxidative stress, fibrosis and inflammation of the cardiac muscle. Hyperglycemia-associated oxidative stress plays an important role in the development ... -
An evaluation of knowledge, attitude and behaviour amongst patients regarding antibiotic use and misuse in South Africa.
(2020)Background: Antibiotic misuse is a global problem that presents a threat to public health. Antibiotic misuse and overuse are responsible for the increase and spread of antibiotic resistance. The community plays a fundamental ... -
In-silico investigation of CREB-binding protein on castration-resistant prostrate cancer: insight from molecular dynamic simulations and computer aided drug discovery.
(2020)Prostate cancer has evolved over the years despite various treatment and therapy. One recent threat of the prostate cancer is the Castration- Resistant Prostate Cancer (CRPC). The CRPC is an advanced form of prostate cancer. ... -
Evaluation of the pharmacodynamic effects of Ketamine on neurotransmitter levels and CREB/BDNF expression in rat brain.
(2020)Mental disorders contribute to 13% of the global burden of disease. With major depressive disorder (MDD) expected to be the most significant contributor by 2030, the economic and social impact of this burden will be ...
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