Predictors of HIV acquisition in high risk women in Durban, South Africa.
Loading...
Date
2015
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
In South Africa young women bear a disproportionate burden of HIV infection however, risk
factors for HIV acquisition are not fully understood in this setting. In a cohort of 245 HIV
negative women, we used proportional hazard regression analysis to examine the association
of demographic, clinical and behavioural characteristics with HIV acquisition. The overall
HIV incidence rate (IR) was 7.20 per 100 women years (wy), 95% Confidence Interval (CI)
4.20–9.80]. Women 18 to 24 years had the highest HIV incidence [IR 13.20 per 100 wy, 95%
CI 6.59–23.62] and were almost three times more likely to acquire HIV compared to women
25 years and older [adjusted Hazard Ratio (aHR) 2.61, 95% CI 1.05–6.47]. Similarly, women
in relationships with multiple sex partners [IR 8.97 per 100 wy, 95% CI 5.40–14.0] had more
than twice the risk of acquiring HIV when compared to women who had no partner or who
had a husband or stable partner (aHR 2.47, 95% CI 0.98–6.26). HIV prevention programmes
must address young women’s vulnerability and promote safer sex practices for high risk
women.
Description
Master of Medical Science in Public Health Medicine. University of KwaZulu-Natal, Howard College 2015.
Keywords
HIV-associated lipodystrophy syndrome--South Africa--Durban., HIV infections--Complications--South Africa--Durban., Antiretroviral agents--South Africa--Durban., HIV-positive women--South Africa--Durban., Theses--Public health medicine., HIV acquisition.