Masters Degrees (Medical Science)
Recent Submissions
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Local experience of patients with connective tissue associated interstitial lung disease who were treated with cyclophosphamide.
(2021)Introduction: Interstitial lung disease (ILD) is a major cause of death amongst individuals with connective tissue diseases (CTD). Although there is no cure for CTD-ILD the need to retard disease progression is vital, ... -
The impact of semen exposure on cytokine response and bacterial vaginosis in the female genital tract.
(2018)Background: Diverse microbial communities and inflammatory cytokine responses in the lower female genital tract (FGT) are closely associated with increased human immunodeficiency virus (HIV-1) risk, possibly through ... -
The role of immunoglobulin isotypes (IgG1-IgG4, IgA AND IgM) in HIV preeclamptics on highly active anti-retroviral therapy, in South Africa.
(2018)Background: The epicentre of a successful pregnancy lies within the placenta and is nurtured by suppressed immune responses. However, the fragile balance between maternal inflammatory responses and the regulation of maternal ... -
The role of vitamin A (retinol palmitate) and beta-carotene on B- lymphocytes and natural killer cells in HIV-1 seropositive pregnant women.
(1998)Abstract available in PDF. -
An investigation into the causes of illness in the 1996 Dusi canoe marathon.
(1997)Abstract available in PDF. -
The changes in immune cells concentration during the progression of pre-diabetes to type 2 diabetes in a diet-induced pre-diabetic rat model.
(2019)T2D has been discovered to be preceded by a long-lasting condition known as prediabetes. The primary cause of prediabetes and T2D has also been shown to be continuous consumption of unhealthy diets and living a sedentary ... -
Evaluation of the Alere Afinion™ AS100 for measuring the levels of C-Reactive Protein in an aged population.
(2020)Introduction The Alere Afinion™ AS100 analyser is a compact bench-top, multi-assay, point-of-care (POC) analyser that provides valuable near patient testing at the point of care. It utilises the latest technology to measure ... -
Genotyping of trichomonas vaginalis in antenatal women from eThekwini.
(2020)Trichomonas vaginalis is the causative agent of trichomoniasis. The genetic characterisation of T. vaginalis isolates reveals significant genetic diversity in this organism. Data on the prevalence of different genotypes ... -
The effects of rhoicissus tridentate dichloromethane extract and its bioactive compounds on uterotonic and glucose lowering activity in-vitro.
(2019)Poor myometrial contractility during labour is associated with an extended partuition process that can affect the neonate’s health status. Chronic use of conventional treatments for diabetes mellitus is sometimes associated ... -
The biological mechanisms associated with Depo-Provera and HIV-1 risk acquisition in women.
(2017)Thirty-six years after the first identification of AIDS, the spread of its aetiological agents continues unabated, human immunodeficiency virus 1 (HIV-1) in particular. About 40% of HIV-1 infections have been reported to ... -
Computational studies of mycobacterium tuberculosis L, d-transpeptidase2.
(2018)Tuberculosis (TB) is still one of the most highly elusive lethal transmittable diseases to eradicate and persist to be a major threat to public health due to emergence of drug resistance. Drug-resistant is steadily increasing ... -
Deoxynivalenol downregulates NRF2-induced cytoprotective response in human hepatocellular carcinoma (HepG2) cells.
(2017)Deoxynivalenol (DON) is a mycotoxin produced by Fusarium species that commonly infect agricultural foods. DON exhibits multiple toxic effects in both animals and humans, binding to the A site of the 28S ribosome and inhibits ... -
In silico studies on Zika NS3 helicase: bedrock for antiviral drug design.
(2017)Zika virus is a re-emerging infectious disease, which was declared to be a public health emergency of international concern due to its various reported complications ranging from microcephaly in newborn to Guillain-Barré ... -
Tissue distribution of an anti-TB drug, TBA-354 in rats via mass spectrometric investigations.
(2016)Tuberculosis (TB) (TB) is one of the most well-recognized ancient human diseases in the history of mankind and it remains the major cause of human death amongst the transmittable diseases despite the use of antitubercular ... -
A comparative chemistry of coa® herbal medicine and herbal extracts of Vernonia Amygdalina (Bitter leaf) and Persea Americana (Avocado).
(2018)The aim of this study is to investigate the phytochemical compounds present in standard COA®, dichloromethane (DCM), ethanol (EtOH), hexane (HEX), and ethyl acetate (EtOAc) , extracts of COA® compared to leaf extracts ... -
In vitro and in vivo evaluation of metal-chelating agents as novel metallo beta-lactamase inhibitors against carbapenem-resistant enterobacteriaceae.
(2018)Infectious diseases remain one of the leading causes of death worldwide, despite the discovery of new and improvements on existing antibiotics. Bacteria are constantly developing sophisticated mechanisms of resisting the ... -
Frequency and phenotype of Immune cell subsets in different regions of the human cervix : implications for HIV susceptibility.
(2018)Abstract available in PDF file. -
Evaluation of the left ventricular ejection fraction post right ventricular pacing at Inkosi Albert Luthuli Central Hospital (IALCH), Durban, KwaZulu-Natal (KZN).
(2016)Since the implantation of the first artificial pacemaker in 1958, these devices have become the treatment of choice in bradycardias. Despite its widespread use, only a few studies have looked at the effects of single chamber ... -
Extrapulmonary tuberculosis at King Edward hospital : a descriptive retrospective study.
(2016)Background Globally, South Africa remains one of the top twenty high tuberculosis(TB) burden countries. In addition, South Africa has the highest burden of tuberculosis/Human Immunodeficiency virus (TB/HIV) coinfection in ...
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