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The role of mir-29a, mir-181a, and mir-222 in preeclamptic and gestational hypertensive patients.
(2017)Backgrounds Hypertensive disorders of pregnancy, a major cause of maternal and neonatal morbidity worldwide are characterized by widespread maternal endothelial dysfunction and metabolic disorders (blood pressure and ... -
The role of endoplasmic reticulum stress in shedding of syncytiotrophoblast microparticles in pregnant black South African women.
(2016)Background and aim: Preeclampsia, accounts for the majority of maternal deaths emanating from hypertension in pregnancy. Although its exact aetiology is unclear, endoplasmic reticulum (ER) stress and trophoblast apoptosis ... -
The relationship between age and diabetes control in patients living with diabetes mellitus in low-to-middle income countries.
(2021)Diabetes Mellitus (DM) is a chronic, metabolic disease characterised by raised blood glucose levels. In 2019, there were an estimated 463 million adult patients living with diabetes (PLWD), with this figure expected to ... -
The prevalence and risk factors for genital mycmoplasmas in Human immunodeficiency virus infected pregnant women from King Edward Vlll hospital.
(2021)Background: Genital mycoplasmas can be found amongst the normal human flora mostly in the respiratory, reproductive and urinary tracts as commensal or pathogenic organisms. These bacteria are sexually transmitted and can ... -
Renal and metabolic effects of tulbaghia violacea harv. and captopril in fructose-fed streptozotocin induced diabetic rats.
(2017)Background: Diabetes mellitus has rapidly emerged as a worldwide epidemic resulting in significant morbidity and mortality. The incidence of type 2 diabetes mellitus, induced by a high carbohydrate diet, a sedentary ... -
“Sugars”: the chemical characterization of a prevalent illicit drug cocktail in South Africa.
(2016)ABSTRACT Introduction “Sugars” is an illicit drug cocktail that is thought to be a mixture of heroin, cocaine and other substances in order to add bulk to the final product. Since its emergence in a local KwaZulu-Natal ... -
Anatomic study of the morphologic relationship between the proximal left and right coronary arteries.
(2016)Arising from the aorta, the right (RCA) and left (LCA) coronary arteries provide the arterial supply to the heart. An extensive literature review revealed that most studies have either evaluated the morphology of the RCA ... -
Evaluation of teixobactin derivatives as potential antimicrobial agents.
(2017)Methicillin resistant Staphylococcus aureus (MRSA) and vancomycin resistant Enterococcus (VRE) are on the World Health Organization (WHO) high priority list of pathogens that require serious attention. Therefore, the ... -
Identification of mutations in genes associated with metronidazole resistance and susceptibility in Trichomonas vaginalis.
(2021)Trichomonas vaginalis is the most common non-viral, sexually transmitted pathogen worldwide. Although, metronidazole cure rates are high for T. vaginalis infection, resistance has been reported. Mutations in the nitroreductase ... -
Local experience of patients with connective tissue associated interstitial lung disease who were treated with cyclophosphamide.
(2021)Introduction: Interstitial lung disease (ILD) is a major cause of death amongst individuals with connective tissue diseases (CTD). Although there is no cure for CTD-ILD the need to retard disease progression is vital, ... -
The impact of semen exposure on cytokine response and bacterial vaginosis in the female genital tract.
(2018)Background: Diverse microbial communities and inflammatory cytokine responses in the lower female genital tract (FGT) are closely associated with increased human immunodeficiency virus (HIV-1) risk, possibly through ... -
The role of immunoglobulin isotypes (IgG1-IgG4, IgA AND IgM) in HIV preeclamptics on highly active anti-retroviral therapy, in South Africa.
(2018)Background: The epicentre of a successful pregnancy lies within the placenta and is nurtured by suppressed immune responses. However, the fragile balance between maternal inflammatory responses and the regulation of maternal ... -
The role of vitamin A (retinol palmitate) and beta-carotene on B- lymphocytes and natural killer cells in HIV-1 seropositive pregnant women.
(1998)Abstract available in PDF. -
An investigation into the causes of illness in the 1996 Dusi canoe marathon.
(1997)Abstract available in PDF. -
The changes in immune cells concentration during the progression of pre-diabetes to type 2 diabetes in a diet-induced pre-diabetic rat model.
(2019)T2D has been discovered to be preceded by a long-lasting condition known as prediabetes. The primary cause of prediabetes and T2D has also been shown to be continuous consumption of unhealthy diets and living a sedentary ... -
Evaluation of the Alere Afinion™ AS100 for measuring the levels of C-Reactive Protein in an aged population.
(2020)Introduction The Alere Afinion™ AS100 analyser is a compact bench-top, multi-assay, point-of-care (POC) analyser that provides valuable near patient testing at the point of care. It utilises the latest technology to measure ... -
Genotyping of trichomonas vaginalis in antenatal women from eThekwini.
(2020)Trichomonas vaginalis is the causative agent of trichomoniasis. The genetic characterisation of T. vaginalis isolates reveals significant genetic diversity in this organism. Data on the prevalence of different genotypes ... -
The effects of rhoicissus tridentate dichloromethane extract and its bioactive compounds on uterotonic and glucose lowering activity in-vitro.
(2019)Poor myometrial contractility during labour is associated with an extended partuition process that can affect the neonate’s health status. Chronic use of conventional treatments for diabetes mellitus is sometimes associated ... -
The biological mechanisms associated with Depo-Provera and HIV-1 risk acquisition in women.
(2017)Thirty-six years after the first identification of AIDS, the spread of its aetiological agents continues unabated, human immunodeficiency virus 1 (HIV-1) in particular. About 40% of HIV-1 infections have been reported to ...