Browsing Masters Degrees (Medical Microbiology) by Title
Now showing items 21-40 of 42
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Investigating the effect of sex hormones on the immune response to TB and HIV.
(2015)Background: Global incidence rates for tuberculosis (TB) indicate a gender-bias to the disease, with almost twice as many men actively infected than women (male/female ratio of 1.9). Sex hormones are known to regulate immune ... -
The isolation of antibiotic survivors in mycobacterium tuberculosis using fluorescence activated cell sorting (FACS).
(2016)Abstract available in PDF file. -
Light forge : a microfluidic high throughput platform for rapid and affordable detection of drug resistant strains of tuberculosis.
(2015)Tuberculosis is one of the most deadly infectious diseases currently plaguing the global community. Unfortunately, lack of accessible, reliable and affordable diagnostic tools in the high disease burden, and resource poor ... -
Methyl picolinic acid plays a role in epigenetic modifications in Human HepG2 liver cells.
(2019)Picolinic Acid (PA) is an endogenous catabolite synthesized from L-Tryptophan via the kynurenine pathway. PA has been reported to possess immunological, neuroprotective, and anti-proliferative properties; however, its most ... -
Microbiology of vaginal discharge with emphasis on gardnerella vaginalis.
(1990)The microbiological aetiology of vaginal discharge was studied in 208 women attending various outpatient clinics at King Edward VIII Hospital. Specimens from the lower genital tract were collected for microscopy and culture. ... -
Microbiology of vaginal discharge with emphasis on gardnerella vaginalis.
(1990)The microbiological aetiology of vaginal discharge was studied in 208 women attending various outpatient clinics at King Edward VIII Hospital. Specimens from the lower genital tract were collected for microscopy and culture. ... -
Microfluidic technologies for capturing and concentrating human immunodeficiency virus-1 (HIV-1) particles.
(2016)HIV-1 RNA assays are routinely used in developed countries to monitor the effectiveness of antiretroviral therapy (ART). These assays require well-trained operators, expensive equipment and reagents, and established ... -
Microfluidic technologies for genomic interrogation of mycobacterium tuberculosis clinical isolates using the polymerase chain reaction (PCR) and high resolution melting analysis (HRMA).
(2015)Background: A number of Mycobacterium tuberculosis (Mtb) genes have been shown to be under positive selection pressure in the presence of anti-TB therapy. This results in the selection of drug resistant phenotypes associated ... -
Migration of Treponema pallidum through a keratinocyte layer.
(2010)Treponema pallidum is the causative agent of the sexually transmitted disease, syphilis. The organism can not be cultured in vitro, which has inhibited the understanding of the pathogenesis of syphilis. There has been no ... -
Molecular epidemiology of antibiotic-resistant enterococcus spp. from farm to food-production chain in intensive poultry production in KwaZulu-Natal, South Africa.
(2019)Extensive antibiotic use in intensively-farmed poultry exerts selection pressure for the emergence of multidrug-resistant pathogens. The aim of this study was to determine the antibiotic resistance and virulence profiles ... -
Mutation frequency in drug-susceptible clinical isolates of Mycobacterium tuberculosis under aerobic and anaerobic conditions.
(2015)Abstract not available. -
Mycobacterium tuberculosis pili (MTP) modulates pathogen and host metabolomic changes in an A549 epithelial cell model of infection.
(2020)Background/Aim: Mycobacterium tuberculosis, the causative organism of tuberculosis, continues to drive research efforts in the quest to develop novel diagnostics and therapeutics. The complexities associated with drug-resistant ... -
Norovirus in children 5 years and below presenting with diarrhoea in KwaZulu-Natal.
(2017)Background - NoVs are single stranded RNA viruses belonging to the family Caliciviridae. They cause gastroenteritis in all age groups but mostly in young children and the elderly. They are classified into seven genogroups ... -
Pathogenic effect of Trichomonas vaginalis on various cell lines in vitro.
(2010)Trichomoniasis has been linked to pelvic inflammatory disease, cervical cancer, increased HIV transmission, infertility as well as co-infections with other STIs. In 2002, an association was found with Trichomonas ... -
Perceived ethionamide resistance in isoniazid susceptible isolates of mycobacterium tuberculosis.
(2015)In Mycobacterium tuberculosis, resistance to ethionamide (ETH) is usually combined with isoniazid (INH) resistance due to a number of mutations in genes that are involved in the biosynthesis of mycolic acids. ETH resistance ... -
Proliferation of klebsiella pneumoniae in medication containing vials for multiple dose medication and intravenous fluids.
(2019)Background and objectives: Klebsiella pneumoniae is frequently implicated in healthcare associated infections. This organism is non–fastidious and easily transmitted in a healthcare environment. Medication fluids are an ... -
Role of local or systemic Schistosoma infections in driving inflammation and HIV risk in women enrolled in the CAPRISA 004 cohort.
(2016)Female genitourinary schistosomiasis (FGS) has been associated with increased HIV susceptibility, presumably through lesions secondary to parasitic eggs in situ in the female genital tract. We determined the prevalence of ... -
The role of mycobacterium tuberculosis pili in pathogenesis : growth and survival kinetics, gene regulation and host immune response, and in vitro growth kinetics.
(2016)Abstract available in PDF file. -
Spatial analysis of HIV infections in high burden sub-districts in KwaZulu-Natal, South Africa.
(2017)Background: Substantial spatial variations in HIV prevalence and incidence at a global, national and district levels have been shown to occur. However, only a few studies have assessed variability of these infections at a ... -
Systemic lymphocyte trafficking markers in TB and TB/HIV co-infections.
(2019)Background. Several studies demonstrate that immune inflammation and trafficking of immune cells to affected tissues plays a major role in the pathogenesis of tuberculosis (TB) and human immunodeficiency virus (HIV) ...