• The effect of HIV and Neisseria gonorrhoeae on the tight junctions of cervical epithelial cells. 

  Maharaj, Shevani. (2020)

  Introduction: Neisseria gonorrhoeae and HIV are major public health concerns globally. The interaction between these diseases is unclear. To determine the effect that N. gonorrhoeae and HIV have on the tight junctions of ...

• Lung tissue resident memory T and B cells in the immune response to Mycobacterium tuberculosis in humans. 

  Ogongo, Paul Ochieng. (2019)

  Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb) is the main cause of death from a single infectious agent. Although a quarter of the world population is estimated to be infected with TB, only 5–10% of these ...

• The interaction between nutrition, immunity and coinfections with human immunodeficiency virus and intestinal parasites in South African adults: investigating the use of prealbumin as a tool for nutritional assessment. 

  Mkhize, Brenda Thabisile. (2019)

  Highly prevalent HIV and helminth single infections continue to plague a significant proportion of the South African population. The geographic overlap of these infections lands to the expectation that high prevalence of ...

• Effect of the capsular material of cryptococcus neoformans on the interplay between Mmicroglial cells and Neutrophils. 

  Bhola, Prathna. (2019)

  Cryptococcal meningitis is an important opportunistic infection in immunocompromised patients. It has been well established that a distinguishing feature of this form of meningitis is a relatively low neutrophil count in ...

• Investigations into the morphometrics, uterine tissue adaptation, maternal fluid biochemistry, heavy metal offloading and early embryonic teeth development impacting the reproductive strategy of the female Ragged-tooth shark (Carcharias taurus) 

  Naidoo, Kristina. (2018)

  Vulnerable” status of ragged-tooth sharks (Carcharias taurus) in South Africa caused by overexploitation, late maturity and low fecundity suggests an intervention to increase the size of this population is needed. Achieving ...

• Metformin alleviates neuronal and renal related stress signals in diabetic C57BL/6 mice. 

  Docrat, Taskeen Fathima. (2019)

  In recent years, diabetes has become more prevalent due to modern, demanding, and sedentary lifestyle patterns. This disease is characterised by insulin resistance and associated molecular complications. Metformin (MF) is ...

• Investigating the in vitro roles played by the major adhesins HBHA and MTP in the pathogenesis of M. tuberculosis, in a novel double gene knock-out mutant strain. 

  Govender, Viveshree Shalom. (2018)

  Abstract available in pdf.

• Molecular epidemiology of antibiotic resistant ESKAPE pathogens isolated from public sector hospitals in uMgungundlovu District, KwaZulu-Natal, South Africa. 

  Zangue, Raspail Carrel Founou. (2017)

  Multi-drug resistant Enterococcus faecium, staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter spp termed ESKAPE pathogens are commonly implicated in ...

• Investigating schistosomiasis markers of inflammation and immune responses in school children on repeated mass drug administration in Bandanyenje, Zimbabwe. 

  Chisango, Tawana Jonathan. (2017)

  Abstract available in PDF file.

• Microchemostat technologies for characterization of efflux pumps associated with multidrug resistance in mycobacterium tuberculosis. 

  Mackenzie, Jared Stuart. (2016)

  Abstract available in PDF file.

• TylA has an essential virulence role in mycobacterium tuberculosis pathogenesis. 

  Sobia, Parveen. (2015)

  Mycobacterium tuberculosis (M.tb), the causative agent of the disease tuberculosis, is an ancient pathogen and a major cause of death worldwide. Although various virulence factors of M.tb have been identified, its pathogenesis ...

• Antibiotic resistance in mycobacterium tuberculosis : the role of genetic mutations in resistance conferring genes and efflux transporters. 

  Dookie, Navisha. (2016)

  Two decades after the World Health Organisation (WHO) declaration of tuberculosis (TB) as a global emergency, the disease remains a public health crisis of epic proportions. The emergence of drug resistant strains of ...

• Improving the efficacy of bacillus calmette guerin vaccine by concomitant inhibition of T regulatory and T helper 2 cells. 

  Kumar, Santosh. (2015)

  Tuberculosis (TB) remains a major threat to human population as currently Mycobacterium tuberculosis (MTB) infects nearly 33% of the global population. Annually, about one and a half million deaths are caused by tuberculosis ...

• Effectiveness of a monovalent human rotavirus vaccine among children of 5 years and under in KwaZulu-Natal. 

  Asowata, Osaretin Emmanuel. (2016)

  Human rotavirus infection is the leading cause of gastroenteritis in infants and young children worldwide. In South Africa, gastroenteritis is a major cause of childhood morbidity and mortality in children less than 5 ...

• Fitness of multi-and extensively drug-resistant mycobacterium tuberculosis clinical strains. 

  Naidoo, Charissa Camille. (2015)

  The biological fitness of a pathogen is defined as its ability to reproduce, survive, cause disease and be transmitted. Drug-resistant M. tuberculosis isolates often exhibit reduced competitive ability against susceptible ...

• Genetic and microrna polymorphisms in young South African Indians with coronary artery disease. 

  Ramkaran, Prithiksha. (2015)

  The global burden of cardiovascular disease (CVD) is on the increase with coronary artery disease (CAD) estimated to become the leading cause of mortality worldwide by 2020. The age of onset of this chronic disorder is on ...

• The impact of sexually transmitted infections (STI) and genital tract inflammation on HIV-1 acquisition and rate of disease progression in subtype C infected women. 

  Mlisana, Koleka Patience. (2014)

  Introduction: Women carry more than half the burden of HIV disease globally and this burden is even higher in sub-Saharan Africa (SSA). Young women, in particular, are at disproportionate risk of HIV infection in South ...

• Immunopathogenesis of vulvo-vaginal candidiasis in human immunodeficiency virus infected women. 

  Apalata, Teke. (2014)

  Vulvovaginal candidiasis (VVC) is an important cause of lower genital tract infections in women. There are currently numerous clinical observations linking increased cases of symptomatic VVC to the progression of HIV ...

• Susceptibility of Trichomonas vaginalis to metronidazole and other compounds. 

  Naidoo, Sarita. (2015)

  Trichomonas vaginalis is the most common sexually transmitted infection caused by a single known organism worldwide; and has been associated with an increased risk of HIV acquisition and transmission. Despite its high ...

• The role of APOBEC3G in acute and early HIV-1 subtype C infection. 

  Reddy, Kavidha. (2014)

  Introduction APOBEC3G and other related cellular cytosine deaminase family members have potent antiviral activity. In the absence of HIV-1 Vif, APOBEC3G mutates the viral DNA during viral reverse transcription. Our knowledge ...

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