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Host induced microevolution of ESX secretion systems of M. Tuberculosis.
(2013)
The ESX family of genes (esxA-W) in Mycobacterium tuberculosis (Mtb) encodes 23 effector
molecules influencing immunogenicity and pathogenicity. This study was aimed at
identifying and evaluating variations in ESX sequence ...
Immunopathogenesis of vulvo-vaginal candidiasis in human immunodeficiency virus infected women.
(2014)
Vulvovaginal candidiasis (VVC) is an important cause of lower genital tract infections in women. There are currently numerous clinical observations linking increased cases of symptomatic VVC to the progression of HIV ...
Evaluation of the MTT and MABA assays for rapid screening of the in vitro activity of synthetic chalcones against Mycobacterium tuberculosis.
(2014)
Background: The chalcone scaffold (1,3-diaryl-2-propen-i-ones) has the advantage of easy chemical modification and has been shown to possess biological activity against a variety of organisms, including a wide range of ...
The isolation of antibiotic survivors in mycobacterium tuberculosis using fluorescence activated cell sorting (FACS).
(2016)
Abstract available in PDF file.
Microchemostat technologies for characterization of efflux pumps associated with multidrug resistance in mycobacterium tuberculosis.
(2016)
Abstract available in PDF file.
Identification of M. tuberculosis pncA gene single nucleotide polymorphisms conferring resistance to pyrazinamide.
(2016)
Abstract available in PDF file.
TylA has an essential virulence role in mycobacterium tuberculosis pathogenesis.
(2015)
Mycobacterium tuberculosis (M.tb), the causative agent of the disease tuberculosis, is an ancient pathogen and a major cause of death worldwide. Although various virulence factors of M.tb have been identified, its pathogenesis ...
Genetic and microrna polymorphisms in young South African Indians with coronary artery disease.
(2015)
The global burden of cardiovascular disease (CVD) is on the increase with coronary artery disease (CAD) estimated to become the leading cause of mortality worldwide by 2020. The age of onset of this chronic disorder is on ...
Improving the efficacy of bacillus calmette guerin vaccine by concomitant inhibition of T regulatory and T helper 2 cells.
(2015)
Tuberculosis (TB) remains a major threat to human population as currently Mycobacterium tuberculosis (MTB) infects nearly 33% of the global population. Annually, about one and a half million deaths are caused by tuberculosis ...
Microfluidic technologies for genomic interrogation of mycobacterium tuberculosis clinical isolates using the polymerase chain reaction (PCR) and high resolution melting analysis (HRMA).
(2015)
Background: A number of Mycobacterium tuberculosis (Mtb) genes have been shown to be under positive selection pressure in the presence of anti-TB therapy. This results in the selection of drug resistant phenotypes associated ...