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Isolation, identification, immunolocalisation and elucidation of the role of plasma kallikrein in human tissues.
Introduction: Plasma kallikrein (PK) is a cofactor in blood coagulation and modulates inflammation through the release of bradykinin (BK). Previously it was believed that plasma prekallikrein (PPK), the precursor of PK ...
Regulation of tumour-angiogenesis by protease inhibitors and receptor antagonists.
Introduction Angiogenesis, the growth of new blood vessels from the pre-existing vasculature, is a pre-requisite for tumour growth and metastasis. Tumour-angiogenesis is regulated by various pro- and anti-angiogenic ...