Browsing Masters Degrees (Medicine) by Title
Now showing items 13-31 of 31
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Deliberate self-harm at RK Khan hospital internal medicine department: the influence of age on the likelihood of admission, triggers, methods used and outcomes.
(2018)A prior suicide attempt is the most important risk factor for complete suicide. For every completed suicide it is estimated that more than 20 suicide attempts are made. From July to December 2016, Deliberate Self-Harm ... -
A description of the profile of the patients and outcomes of fiber-optic bronchoscopies, performed at a tertiary care hospital in KwaZulu-Natal, South Africa, from January to December 2011.
(2014)Background Tuberculosis (TB), pneumonia and human immunodeficiency virus (HIV) were the three leading causes of natural deaths in South Africa in 2013 and 11.9% of all deaths in KwaZulu Natal were attributed to TB. In ... -
Faecal carriage of extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella spp. in Mozambican students.
(2017)In recent years, the world has seen a surge in extended-spectrum β-lactamase (ESBL)-producing bacteria. Among antibiotic resistance mechanisms, the production of β-lactamase is the most rapidly developing and clinically ... -
Genetic basis of steroid resistant nephrotic syndrome in Indian and Black South African children.
(2017)Abstract available in PDF file. -
Human T cell lymphotropic virus 1 associated infective dermatitis in KwaZulu-Natal, South Africa.
(2008)Background Human T cell Lymphotropic Virus Type I (HTLV-I) associated infective dermatitis, first described by Sweet in Jamaican children, is a pattern of eczema characterized by exudation, crusting around the ... -
An immunocytochemical study of the kallikrein-kinin system on the circulating neutrophil.
(1996)Inflammation is the normal biological response to tissue injury, and is characterised by the interactive activation of multiple mediators and cell types. One response to tissue injury is the production of pain, not only ... -
Isolation, identification, immunolocalisation and elucidation of the role of plasma kallikrein in human tissues.
(2000)Introduction: Plasma kallikrein (PK) is a cofactor in blood coagulation and modulates inflammation through the release of bradykinin (BK). Previously it was believed that plasma prekallikrein (PPK), the precursor of PK ... -
A novel study to detect and quantify microorganisms associated with bacterial vaginosis from urine samples.
(2019)Bacterial vaginosis (BV) is the most common vaginal condition found in women of reproductive age. The lack of published data on the detection of BV-associated pathogens from urine, a non-invasive sample, lends novelty to ... -
PreNatal nicotine exposure and maternal separation alter the nicotinic acetylcholine receptors in mice.
(2019)Maternal cigarette smoking during pregnancy has been associated with long term cognitive dysfunction. The harmful behavioural effects of cigarette smoking have been shown to be primarily due to nicotine. While the mechanism ... -
Quantitative susceptibility testing of chlamydia trachomatis against clinically relevant drugs.
(2017)Abstract available in PDF file. -
Regulation of tumour-angiogenesis by protease inhibitors and receptor antagonists.
(2012)Introduction Angiogenesis, the growth of new blood vessels from the pre-existing vasculature, is a pre-requisite for tumour growth and metastasis. Tumour-angiogenesis is regulated by various pro- and anti-angiogenic ... -
Renal manifestations of human immunodeficiency virus in the era of antiretroviral treatment in South Africa.
(2016)Background: Sub-Saharan Africa carries the global burden of human immunodeficiency virus (HIV) infection. Renal disease is a well-recognized and closely associated complication of HIV infection. The burden of kidney disease ... -
A retrospective review of the clinical outcomes in patients admitted to a newly established medical High Care Unit at King Edward VIII Hospital.
(2016)Abstract available in PDF file. -
A retrospective review of the demographic profile, disease activity, co-existent co-morbid disease and treatment in established rheumatoid arthritis at a tertiary center clinic.
(2016)Rheumatoid arthritis (RA) is one of the most common forms of chronic inflammatory arthritis and often results in joint damage, physical disability and premature mortality. The incidence of RA is increasing in developing ... -
The role of follistatin and granulocyte-colony stimulating factor in HIV-associated pre-eclampsia.
(2018)KZN has a high burden of HIV infection and high blood pressure, specifically pre-eclampsia (PE) in pregnancy. Follistatin (FS) and granulocyte-colony stimulating factor (G-CSF) are two glycoproteins involved in PE pathogenesis. ... -
Size does not matter: a molecular insight into the biological activity of chemical fragments utilizing computational approaches.
(2016)Insight into the functional and physiological state of a drug target is of essential importance in the drug discovery process, with the lack of emerging (3D) drug targets we propose the integration of homology modeling ... -
Transforming growth factor βeta 1-3 in HIV associated pre-eclampsia.
(2017)Introduction: Pre-eclampsia is a clinical syndrome that complicates approximately 3-8% of all pregnancies and is the second leading cause of maternal mortality. The maternal imbalance of pro-angiogenic and anti-angiogenic ... -
Warfarin : time in therapeutic range, a single centre study on patients using warfarin for stroke prevention in non-valvular atrial fibrillation and prosthetic heart valves.
(2016)Background: There are various indications for the use of oral anticoagulants. Two common indications are in patients with atrial fibrillation and prosthetic heart valves. The quality of anticoagulation, determined by the ...