Browsing Doctoral Degrees (Biochemistry) by Title
Now showing items 47-66 of 75
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Neutrophil tissue inhibitor of matrix metalloproteinases-1 (TIMP- 1) : novel localisation, mobilisation and possible role.
(2002)At the beginning of this study, the granule localisation and regulation of release of human neutrophil (PMNL) precursor collagenases, proMMP-8 and -9 (type I and type TV/V collagenases, respectively), enzymes highly ... -
Novel epidermal growth factor directed cationic lipoplexes promote in vitro hepatotropic gene targeting.
(2014)The need for the improvement in protocols for cellular gene delivery has propelled cytofectin based liposomes as suitable non-viral gene carriers. The amenability of cationic liposomes to modification enables research based ... -
The nutritive value of Italian ryegrass (Lolium multiflorum) selected for high dry matter and nonstructural carbohydrate contents.
(2003)In traditional forage breeding programmes, breeders have spent decades improving the agronomic characteristics of grasses, such as herbage yield, persistence and resistance to diseases, without considering the nutrient ... -
The occurrence of mycotoxins in feedstuffs in Natal and aspects of their metabolism in the rumen.
(1985)The fluorodinitrobenzene (FONB), succinic anhydride (SA), dansyl chloride (DAN), dye-binding lysine (OBL), total lysine (TL), ninhydrin (NIN) and Tetrahymena lysine (TET) methods were compared for their ability to ... -
Plasmodium yoelii acetyl-coa carboxylase : detection and characterisation of the recombinant biotinoyl domain.
(2008)Human malaria, caused by four species of the intracellular protozoan parasite Plasmodium, is a major health and economic burden in the tropics where the disease is endemic. The biotindependent enzyme acetyl-CoA carboxylase ... -
The presentation and interpretation of arrow symbolism in biology diagrams at secondary-level.
(2006)The literature contains conflicting ideas about the effectiveness of diagrams, and their constituent symbolism as teaching and learning tools. In addition, only limited research has been specifically conducted on the ... -
Properties of Cathepsin L in relation to a role in invasive cancer.
(1998)Cathepsin L, which has been implicated in many tissue degradative pathologies by virtue of its ability to degrade extracellular matrix components, was isolated by a novel, scaled-up protein purification method and purified ... -
Proteinases and extracellular matrix degradation in breast cancer.
(1996)A variety of proteases have been shown to promote the progression of cancer by virtue of their ability to degrade extracellular proteinaceous barriers, such as basement membrane and interstitial stroma. At the outset of ... -
Quantitative imaging of tyrosine kinase-drug interactions in cells.
(2012)Kinases play a crucial role in regulating cellular signaling cascades, making them therapeutic targets for several human diseases. In human cancers, mis-regulation and mutations of kinases such as EGFR (epidermal growth ... -
Receptor targeted gene delivery using folate ligand conjugated cationic liposomes.
(2014)Gene therapy has become an important strategy to treat several human diseases, including cancer, viral infections and inherited disorders. In response to this growing trend, a number of gene delivery vectors have been ... -
Recombinant expression and initial characterisation of two Plasmodium copper binding proteins.
(2011)Plasmodium falciparum is a protozoan parasite responsible for the most severe form of human malaria, with infection often resulting in death. Efforts to control malaria have been hindered by an increased spread of parasite ... -
A serine oligopeptidase from African Trypanosomes.
(1998)Protozoan parasites of the genus Trypanosoma are responsible for chronic and widespread disease in livestock and humans in Africa. This study describes the purification and characterisation of a serine oligopeptidase ... -
Some aspects of development and cell wall properties of the desiccation-sensitive embryos of Encephalartos natalensis (Zamiaceae)
(2013)The present investigation can be divided into two main sections: the first dealing with the post-shedding embryogenesis of Encephalartos natalensis and the second concerned with the cell wall properties of immature and ... -
Some aspects of the role of rat liver ribosomes in protein biosynthesis.
(1969)No abstract available. -
Starburst poly-amidoamine dendrimer grafted gold nanoparticles as scaffolds for targeted gene delivery in vitro.
(2017)Abstract available in PDF file. -
Studies on a multicatalytic, protease complex from Trypanosoma brucei brucei.
(1999)Subcellular fractionation (together with immunocytochemical localisation studies) showed that the parasite Trypanosoma brucei brucei possesses a multicatalytic protease complex (MCPTb). This complex is predominantly ... -
Studies on acid phosphatases of Trypanosoma congolense.
(1997)Bloodstream forms of African trypanosomes, which endocytose macromolecules exclusively through their flagellar pockets, contain an acid phosphatase (AcP) activity in this organelle. In the present thesis, AcP activity ... -
Studies on the anti-hyperglycemic potentials and possible mode of actions of some commonly used sugar alcohols.
(2016)Abstract available in PDF file. -
Studies on the coupling of DNA to low density lipoproteins (LDL) and the interaction of these complexes with eukaryotic cells.
(1987)The application of Molecular Biochemistry for transfection studies in eukaryotic systems is well documented. Of the numerous methods employed for the introduction of foreign DNA into eukaryotic cells, the use of low ...