Browsing Doctoral Degrees (Biochemistry) by Title
Now showing items 22-41 of 75
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Ecophysiological studies of the invasive weed Chromolaena odorata (L.) King and Robinson and its control in KwaZulu-Natal.
(2013)Despite increased interest in the control and spread of the alien weed, Chromolaena odorata, little is known of its photosynthetic characteristics under field conditions. The aim of the study was to obtain a better ... -
Effect of antimalarial drugs and malaria pigment ( *-haematin) on monocyte phagocytosis and GTP-cyclohydrolase 1 gene expression.
(2009)During the erythrocytic stage, the malaria parasite digests host cell haemoglobin into amino acids. Toxic haeme is released and is incorporated into an insoluble non-toxic crystal called haemozoin. Haemozoin is released ... -
Effect of c-Ha-ras(V12) on protease trafficking in invasive breast cancer cells.
(2009)Effect of c-Ha-ras(V12) on cathepsin trafficking in invasive breast cancer cells. Various mutations of Ha-ras together with lack of p53-related control over cell cycle progression, result in an immortal, tumorigenic ... -
Effect of nitrate upon the digestibility of kikuyu grass (Pennisetum clandestinum)
(1985)The factors affecting the accumulation of nitrate in kikuyu grass pastures and the effect of elevated nitrate levels upon digestion in the ruminant were investigated. A high potassium level in the soil seems to be the ... -
Endolysosomal proteolysis and its regulation.
(2003)The endolysosomal system is a multifunctional system and is involved in catabolism, antigen presentation and regulation of hormones. The descriptions of, and functions assigned to organelles within the system are often ... -
Enzymatic conversion of sterigmatocystin to aflatoxin B1.
(1984)The age of Aspergillus parasiticus (1-11-105Wh1) mycelium was found to have an influence on the level of enzymes, responsible for the conversion of sterigmatocystin to aflatoxin B[1] and O-methylsterigmatocystin, present. ... -
Evaluation of the anti-diabetic potentials of some African medicinal plants: a multimode study.
(2018)The present study investigated the effects of five African medicinal plants (Alstonia boonei, Acalypha wilkesiana, Boerhaavia diffusa, Bridelia ferruginea, and Crassocephalum rubens) for their antioxidative and antidiabetic ... -
Expression of monocyte heat shock protein 70 (HSP70) during malaria fever in the presence of antimalarial, anti-inflammatory drugs and β-haematin.
(2017)Abstract available in PDF file. -
Extracellular matrix factors influence myoblast activation, differentiation and fusion.
(2015)Satellite cells are muscle stem cells that reside in a niche between the basal lamina and sarcolemma of mature muscle fibers. Upon muscle injury, these cells are activated to myoblasts that subsequently proliferate, ... -
The extracellular matrix regulates myoblast migration during wound healing.
(2012)Mammalian skeletal muscle can regenerate after injury and this response is primarily mediated by the satellite cell, a muscle stem cell. Following injury, satellite cells are activated to myoblasts, undergo rapid ... -
Factors governing seed recalcitrance in two species of contrasting storage longevity.
(2017)Abstract available in PDF file. -
Functionalised gold nanoparticle delivery for c-MYC siRNA in cancer gene therapy.
(2018)Abstract available in PDF file. -
Gene disruption of TcoCATL (Congopain) and oligopeptidase B, pathogenic factors of African trypanosomes.
(2011)African trypanosomosis is a parasitic disease in man and animals caused by protozoan parasites of the genus Trypanosoma. T. congolense, T. vivax and T. brucei brucei cause nagana in cattle. The variable nature of the ... -
Gene transfer by receptor-mediated endocytosis : stable expression of NEO following insulin-directed entry into HepG2 cells.
(1989)Evidence is presented for DNA delivery to cultured HepG2 hepatoma cells via the endocytotic pathway, under the direction of insulin, in a soluble system of transfection leading to stable gene expression. Serum albumin ... -
Identification and characterisation of novel pathogenic factors of Trypanosoma congolense.
(2010)Trypanosoma congolense is a major causative agent of the bovine disease trypanosomosis which has a considerable economic impact on sub-Saharan Africa. Current control methods for trypanosomosis are unsatisfactory and ... -
The in vitro and in vivo anti-oxidative and anti-diabetic effects of some African medicinal plants and the identification of the bioactive compounds.
(2013)This thesis examined the in vitro and in vivo anti-oxidative and anti-diabetic activities of five African medicinal plants which are traditionally used for the treatment of diabetes mellitus viz; Ziziphus mucronata, Cassia ... -
An investigation into the analytical, cytotoxicity and immunotoxicity of mycotoxins found in commercially available pelleted pet foods in Durban, South Africa.
(2018)Introduction: Dry pelleted dog food in the South African market is available via supermarket, pet stores (standard brands - SB) and veterinary channels (premium brands-PB). Similarly, cat food were viewed in two market ... -
Investigation of anti-diabetic properties of Psidium guajava leaf in streptozocin induced diabetic rats.
(2015)Diabetes mellitus results in chronic hyperglycaemia, leading to defects in carbohydrate, fat and protein metabolism. Diabetes mellitus is also linked with elevated plasma cholesterol and triglyceride levels, which may ...