Browsing Caprisa (Centre for the Aids programme of research in South Africa) by Advisor "Walker, Bruce D."
Now showing items 1-4 of 4
Association of TRIM22 with the Type 1 Interferon Response and Viral Control during Primary HIV-1 Infection. (American Society for Microbiology., 2010)Type 1 interferons (IFNs) induce the expression of the tripartite interaction motif (TRIM) family of E3 ligases, but the contribution of these antiviral factors to HIV pathogenesis is not completely understood. We hypothesized ...
CD8+ T cell breadth and ex vivo virus inhibition capacity distinguish between viremic controllers with and without protective HLA class I alleles. (American Society for Microbiology., 2016)Abstract available in PDF file.
(American Society for Microbiology., 2012)Certain immune-driven mutations in HIV-1, such as those arising in p24Gag, decrease viral replicative capacity. However, the intersubtype differences in the replicative consequences of such mutations have not been explored. ...
Nef-mediated down-regulation of CD4 and HLA class I in HIV-1 subtype C infection: association with disease progression and influence of immune pressure. (Elsevier., 2014)Abstract available in pdf.