Browsing Caprisa (Centre for the Aids programme of research in South Africa) by Title

Now showing items 393-412 of 447

    • Structural constraints of vaccine-induced tier-2 autologous HIV neutralizing antibodies targeting the receptor-binding site. 

      Bradley, Todd.; Fera, Daniela.; Bhiman, Jinal N.; Eslamizar, Leila.; Lu, Xiaozhi.; Anasti, Kara.; Zhang, Ruijung.; Sutherland, Laura L.; Scearce, Richard M.; Bowman, Cindy M.; Stolarchuk, Christina.; Lloyd, Krissey E.; Parks, Robert.; Eaton, Amanda.; Foulger, Andrew.; Nie, Xiaoyan.; Abdool Karim, Salim Safurdeen.; Barnett, Susan.; Kelsoe, Garnett.; Kepler, Thomas B.; Alam, Shabnam Munir.; Montefiori, David C.; Moody, Michael Anthony.; Liao, Hua-Xin.; Morris, Lynn.; Santra, Sampa.; Harrison, Stephen C.; Haynes, Barton F. (Cell Press., 2016)
      Abstract available in pdf.

    • Structure and immune recognition of trimeric pre-fusion HIV-1 Env. 

      Pancera, Marie.; Zhou, Tongqing.; Druz, Aliaksandr.; Georgiev, Ivelin S.; Soto, Cinque.; Gorman, Jason.; Huang, Jinghe.; Acharya, Priyamvada.; Chuang, Gwo-Yu.; Ofek, Gilad.; Stewart-Jones, Guillaume B. E.; Stuckey, Jonathan.; Bailer, Robert T.; Joyce, M. Gordon.; Louder, Mark K.; Tumba, Nancy.; Yang, Yongping.; Zhang, Baoshan.; Cohen, Myron S.; Haynes, Barton F.; Mascola, John R.; Morris, Lynn.; Munro, James B.; Blanchard, Scott C.; Mothes, Walther.; Connors, Mark.; Kwong, Peter D. (Macmillan Publishers Limited., 2014)
      The human immunodeficiency virus type 1 (HIV-1) envelope (Env) spike, comprising three gp120 and three gp41 subunits, is a conformational machine that facilitates HIV-1 entry by rearranging from a mature unliganded state, ...

    • Structure and recognition of a novel HIV-1 gp120-gp41 interface antibody that caused MPER exposure through viral escape. 

      Wibmer, Constantinos Kurt.; Gorman, Jason.; Ozorowski, Gabriel.; Bhiman, Jinal N.; Sheward, Daniel J.; Elliott, Debra H.; Rouelle, Julie.; Smira, Ashley.; Joyce, M. Gordon.; Ndabambi, Nonkululeko.; Druz, Aliaksandr.; Asokan, Mangai.; Burton, Dennis R.; Connors, Mark.; Abdool Karim, Salim Safurdeen.; Mascola, John R.; Robinson, James E.; Ward, Andrew B.; Williamson, Carolyn.; Kwong, Peter D.; Morris, Lynn.; Moore, Penny L. (Public Library of Science., 2017)
      Abstract available in pdf.

    • Structure of an N276-dependent HIV-1 neutralizing antibody targeting a rare V5 glycan hole adjacent to the CD4 binding site. 

      Wibmer, Constantinos Kurt.; Gorman, Jason.; Anthony, Colin S.; Mkhize, Nonhlanhla N.; Druz, Aliaksandr.; York, Talita.; Schmidt, Stephen D.; Labuschagne, Phillip.; Louder, Mark K.; Bailer, Robert T.; Abdool Karim, Salim Safurdeen.; Mascola, John R.; Williamson, Carolyn.; Moore, Penny L.; Kwong, Peter D.; Morris, Lynn. (American Society for Microbiology., 2016)
      Abstract available in pdf.

    • Substitution of Moxifloxacin for Isoniazid during intensive phase treatment of Pulmonary Tuberculosis. 

      Dorman, Susan E.; Johnson, John L.; Goldberg, Stefan.; Muzanye, Grace.; Padayatchi, Nesri.; Bozeman, Lorna.; Heilig, Charles M.; Bernardo, John.; Choudhri, Shurjeel.; Grosset, Jacques H.; Guy, Elizabeth.; Guyadeen, Priya.; Leus, Maria Corazon.; Maltas, Gina.; Menzies, Dick.; Nuermberger, Eric L.; Villarino, Margarita.; Vernon, Andrew.; Chaisson, Richard E. (American Thoracic Society., 2009)
      Rationale: Moxifloxacin has potent activity against Mycobacterium tuberculosis in vitro and in a mouse model of antituberculosis (TB) chemotherapy, but data regarding its activity in humans are limited. Objectives: Our ...

    • Surgical treatment of complications of pulmonary tuberculosis, including drug-resistant tuberculosis. 

      Madansein, Rajhmun.; Parida, Shreemanta.; Padayatchi, Nesri.; Singh, Nalini.; Master, Iqbal.; Naidu, Kantharuben.; Zumla, Alimuddin.; Maeurer, Markus. (Elsevier., 2015)
      Abstract available in pdf.

    • Survey of ethical dilemmas facing intensivists in South Africa in the admission of patients with HIV infection requiring intensive care. 

      Naidoo, Kogieleum.; Singh, Jerome Amir.; Lalloo, Umesh Gangaram. (Health & Medical Publications Group., 2013)
      Background. Maturing of the burgeoning HIV epidemic in South Africa has resulted in an increased demand for intensive care. Objectives. To investigate the influence of ethical dilemmas facing South African intensivists on ...

    • Sustainability of task-shifting for antiretroviral treatment. 

      Naranbhai, Vivek.; Abdool Karim, Quarraisha.; Naidoo, Kogieleum.; Yende Zuma, Nonhlanhla.; Abdool Karim, Salim Safurdeen. (Elsevier., 2012)
      No abstract available.

    • Symptomatic vaginal discharge is a poor predictor of sexually transmitted infections and genital tract inflammation in high-risk women in South Africa. 

      Mlisana, Koleka Patience.; Naicker, Nivashnee.; Werner, Lise.; Roberts, Lindi.; Van Loggerenberg, Francois.; Baxter, Cheryl.; Passmore, Jo-Ann Shelley.; Grobler, Anna Christina.; Sturm, Adriaan Willem.; Williamson, Carolyn.; Ronacher, Katharina.; Walzl, Gerhard.; Abdool Karim, Salim Safurdeen. (Oxford University Press., 2011)
      Background. Diagnosis and treatment of sexually transmitted infections (STIs) is a public health priority, particularly in regions where the incidence of human immunodeficiency virus (HIV) infection is high. In most ...

    • A systematic review of definitions of extreme phenotypes of HIV control and progression. 

      Gurdasani, Deepti.; Iles, Louise.; Dillon, David G.; Young, Elizabeth H.; Olson, Ashley D.; Naranbhai, Vivek.; Fidler, Sarah.; Gkrania-Klotsas, Effrossyni.; Post, Frank A.; Kellam, Paul.; Porter, Kholoud.; Sandhu, Manjinder S. (Wolters Kluwer Health., 2014)
      The study of individuals at opposite ends of the HIV clinical spectrum can provide invaluable insights into HIV biology. Heterogeneity in criteria used to define these individuals can introduce inconsistencies in results ...

    • Targeted screening of at-risk adults for acute HIV-1 infection in sub-Saharan Africa. 

      Sanders, Eduard J.; Wahome, Elizabeth.; Powers, Kimberly A.; Werner, Lise.; Fegan, Greg.; Lavreys, Ludo.; Mapanje, Clement.; McClelland, Scott.; Garrett, Nigel Joel.; Miller, William C.; Graham, Susan M. (Wolters Kluwer., 2015)
      Abstract available in pdf.

    • TB epidemiology: where are the young women? Know your tuberculosis epidemic, know your response. 

      Perumal, Rubeshan.; Naidoo, Kogieleum.; Padayatchi, Nesri. (BioMed Central., 2018)
      Abstract available in pdf.

    • TB treatment outcomes following directly-observed treatment at an urban outpatient specialist TB facility in South Africa. 

      Kharsany, Ayesha Bibi Mahomed.; Olowolagba, Ayo.; Abdool Karim, Salim Safurdeen.; Abdool Karim, Quarraisha.; Connolly, Catherine. (Sage., 2006)
      The treatment of 450 consecutive new patients with pulmonary TB was evaluated to determine outcome following directly-observed treatment. In all,176 (39.1%) patients were cured, 23 (5.1%) completed treatment, 80 (17.8%) ...

    • TB/HIV: an orphan disease? 

      Brust, James C. M.; O'Donnell, Max Roe.; Metcalfe, John Z. (American Thoracic Society., 2011)
      No abstract available.

    • Temporal association of HLA-B*81:01- and HLA-B*39:10-mediated HIV-1 p24 sequence evolution with disease progression. 

      Ntale, Roman.; Chopera, Denis Rutendo.; Ngandu, Nobubelo K.; de Assis Rosa, Debra.; Zembe, Lycias.; Gamieldien, Hoyam.; Mlotshwa, Mandla.; Werner, Lise.; Woodman, Zenda.; Mlisana, Koleka Patience.; Abdool Karim, Salim Safurdeen.; Gray, Clive M.; Williamson, Carolyn. (American Society for Microbiology., 2012)
      HLA-B*81:01 and HLA-B*39:10 alleles have been associated with viremic control in HIV-1 subtype C infection. Both alleles restrict the TL9 epitope in p24 Gag, and cytotoxic-T-lymphocyte (CTL)-mediated escape mutations in ...

    • Ten-year review of research in South Africa : government is tackling the R&D crisis caused by a shift of focus to service delivery. 

      Singh, Jerome Amir. (Nature publishing Group., 2004)
      No abstract available.

    • Tenofovir gel for the prevention of herpes simplex virus type 2 infection. 

      Abdool Karim, Salim Safurdeen.; Abdool Karim, Quarraisha.; Kharsany, Ayesha Bibi Mahomed.; Baxter, Cheryl.; Grobler, Anna Christina.; Werner, Lise.; Kashuba, Angela D. M.; Mansoor, Leila Essop.; Samsunder, Natasha.; Mindel, Adrian.; Gengiah, Tanuja Narayansamy. (Massachusetts Medical Society., 2015)
      Abstract available in pdf.

    • Tenofovir-based preexposure prophylaxis for HIV infection among African women. 

      Marrazzo, Jeanne M.; Ramjee, Gita.; Richardson, Barbra A.; Gomez, Kailazarid.; Mgodi, Nyaradzo.; Nair, Gonasagrie.; Palanee, Thesla.; Nakabiito, Clemensia.; van der Straten, Ariane.; Noguchi, Lisa M.; Hendrix, Craig W.; Dai, James Y.; Ganesh, Shayhana.; Mkhize, Baningi.; Taljaard, Marthinette.; Parikh, Urvi M.; Piper, Jeanna.; Mâsse, Benoît.; Grossman, Cynthia.; Rooney, James.; Schwartz, Jill L.; Watts, Heather D.; Marzinke, Mark A.; Hillier, Sharon L.; McGowan, Ian M.; Chirenje, Zvavahera Mike. (Massachusetts Medical Society., 2015)
      Abstract available in pdf.

    • Time for gender mainstreaming in editorial policies. 

      Heidari, Shirin.; Eckert, Mirjam J.; Kippax, Susan.; Abdool Karim, Quarraisha.; Sow, Papa Salif.; Wainberg, Mark A. (International AIDS Society., 2011)
      The HIV epidemic has been continuously growing among women, and in some parts of the world, HIV-infected women outnumber men. Women’s greater vulnerability to HIV, both biologically and socially, influences their health ...

    • Timing of initiation of antiretroviral drugs during tuberculosis therapy. 

      Abdool Karim, Salim Safurdeen.; Naidoo, Kogieleum.; Grobler, Anna Christina.; Padayatchi, Nesri.; Baxter, Cheryl.; Gray, Andrew Lofts.; Gengiah, Tanuja Narayansamy.; Nair, Gonasagrie.; Bamber, Sheila.; Singh, Aarthi.; Khan, Munira.; Pienaar, Jacqueline C.; El-Sadr, Wafaa.; Friedland, Gerald H.; Abdool Karim, Quarraisha. (Massachusetts Medical Society., 2010)
      Background. The rates of death are high among patients with coinfection with tuberculosis and the human immunodeficiency virus (HIV). The optimal timing for the initiation of antiretroviral therapy in relation to tuberculosis ...