Browsing Caprisa (Centre for the Aids programme of research in South Africa) by Title
Now showing items 435-448 of 448
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V2-directed vaccine-like antibodies from HIV-1 infection identify an additional K169-binding light chain motif with broad ADCC activity.
(Cell Press., 2018)Abstract available in pdf. -
Vaginal bacteria modify HIV tenofovir microbicide efficacy in African women.
(American Association for the Advancement of Science., 2017)Abstract available in pdf. -
Vertical T cell immunodominance and epitope entropy determine HIV-1 escape.
(American Society for Clinical Investigation., 2012)HIV-1 accumulates mutations in and around reactive epitopes to escape recognition and killing by CD8+ T cells. Measurements of HIV-1 time to escape should therefore provide information on which parameters are most important ... -
Viral escape from HIV-1 neutralizing antibodies drives increased plasma neutralization breadth through sequential recognition of multiple epitopes and immunotypes.
(Plos., 2013)Identifying the targets of broadly neutralizing antibodies to HIV-1 and understanding how these antibodies develop remain important goals in the quest to rationally develop an HIV-1 vaccine. We previously identified a ... -
Viral variants that initiate and drive maturation of V1V2-directed HIV-1 broadly neutralizing antibodies.
(Nature Publishing Group., 2015)Abstract available in pdf. -
Virological and Immunological Factors Associated with HIV-1 Differential Disease Progression in HLA-B*58:01-Positive Individuals.
(American Society for Microbiology., 2010)Molecular epidemiology studies have identified HLA-B*58:01 as a protective HIV allele. However, not all B*58:01-expressing persons exhibit slow HIV disease progression. We followed six HLA-B*58:01-positive, HIV subtype ... -
Virological features associated with the development of broadly neutralizing antibodies to HIV-1.
(Elsevier Ltd., 2015)Abstract available in pdf. -
When to start antiretroviral therapy during tuberculosis treatment?
(Lippincott Williams & Wilkins., 2012)Purpose of review. Effective treatment exists for tuberculosis (TB) and for HIV, but treating both diseases simultaneously presents several challenges. This review assesses the evidence for the timing of antiretroviral ... -
“When treatment is more challenging than the disease” : a qualitative study of MDR-TB patient retention.
(Public Library of Science., 2016)Abstract available in PDF file. -
Which new health technologies do we need to achieve an end to HIV/AIDS?
(Public Library of Science., 2016)Abstract available in PDF file. -
Why human health and health ethics must be central to climate change deliberations.
(Plos., 2012)No abstract available. -
Women with pregnancies had lower adherence to 1% Tenofovir vaginal gel as HIV preexposure prophylaxis in CAPRISA 004, a phase IIB randomized-controlled trial.
(Plos., 2013-03)Background: Antiretroviral prophylaxis may be a critical strategy to reduce periconception HIV transmission. Maximizing the benefit of periconception pharmacologic HIV risk-reduction requires an understanding of the links ... -
XDR-TB in South Africa : no time for denial or complacency.
(Plos., 2007)On September 1, 2006, the World Health Organisation (WHO) announced that a deadly new strain of extensively drug-resistant tuberculosis (XDR-TB) had been detected in Tugela Ferry (Figure 1), a rural town in the South African ... -
Y chromosome and HIV DNA detection in vaginal swabs as biomarkers of semen and HIV exposure in women.
(Wolters Kluwer., 2014)Abstract available in pdf.