Browsing Caprisa (Centre for the Aids programme of research in South Africa) by Title

Now showing items 373-392 of 448

Safety and effectiveness of BufferGel and 0.5% PRO 2000 gel for the prevention of HIV infection in women.

Abdool Karim, Salim Safurdeen.; Richardson, Barbra A.; Ramjee, Gita.; Hoffman, Irving F.; Chirenje, Zvavahera Mike.; Taha, Taha E.; Kapina, Muzala.; Maslankowski, Lisa.; Coletti, Anne S.; Profy, Albert.; Moench, Thomas R.; Piwowar-Manning, Estelle.; Masse, Benoit.; Hillier, Sharon L.; Soto-Torres, Lydia. (Lippincott Williams & Wilkins., 2010)

Objective: To determine the safety and effectiveness of BufferGel and 0.5% PRO2000 microbicide gels for the prevention of male-to-female HIV transmission. Design: Phase II/IIb, randomized, placebo-controlled trial with ...
Safety and efficacy of the HVTN 503/Phambili Study of a clade-B-based HIV-1 vaccine in South Africa: a double-blind, randomised, placebo-controlled test-of-concept phase 2b study.

Gray, Glenda E.; Allen, Mary.; Moodie, Zoe.; Churchyard, Gavin J.; Bekker, Linda-Gail.; Nchabeleng, Maphoshane.; Mlisana, Koleka Patience.; Metch, Barbara.; De Bruyn, Guy.; Latka, Mary H.; Roux, Surita.; Mathebula, Matsontso.; Naicker, Nivashnee.; Ducar, Constance.; Carter, Donald K.; Puren, Adrian.; Eaton, Niles.; McElrath, M. Juliana.; Robertson, Michael.; Corey, Lawrence.; Kublin, James. (Elsevier., 2011)

Background. The MRKAd5 HIV-1 gag/pol/nef subtype B vaccine was designed to elicit T-cell-mediated immune responses capable of providing complete or partial protection from HIV-1 infection or a decrease in viral load after ...
Safety of tenofovir gel, a vaginal microbicide, in South African women: results of the CAPRISA 004 Trial.

Sokal, David C.; Abdool Karim, Quarraisha.; Sibeko, Sengeziwe.; Yende Zuma, Nonhlanhla.; Mansoor, Leila Essop.; Baxter, Cheryl.; Grobler, Anna Christina.; Fröhlich, Janet Ann.; Kharsany, Ayesha Bibi Mahomed.; Miya, Nomsa.; Mlisana, Koleka Patience.; Maarschalk, Silvia.; Abdool Karim, Salim Safurdeen. (International Medical Press., 2012)

Background: Tenofovir gel, used vaginally before and after coitus, reduced women’s acquisition of HIV by 39%. This is a safety assessment of tenofovir gel, including renal, bone, gastrointestinal, genital and haematological ...
Safety, tolerability, and pharmacokinetics of long-acting injectable cabotegravir in low-risk HIV-uninfected individuals: HPTN 077, a phase 2a randomized controlled trial.

Landovitz, Raphael J.; Li, Sue.; Grinsztejn, Beatriz.; Dawood, Halima.; Liu, Albert Y.; Magnus, Manya.; Hosseinipour, Mina C.; Panchia, Ravindre.; Cottle, Leslie.; Chau, Gordon.; Richardson, Paul.; Marzinke, Mark A.; Hendrix, Craig W.; Eshleman, Susan H.; Zhang, Yinfeng.; Tolley, Elizabeth.; Sugarman, Jeremy.; Kofron, Ryan.; Adeyeye, Adeola.; Burns, David.; Rinehart, Alex R.; Margolis, David.; Spreen, William R.; Cohen, Myron S.; McCauley, Marybeth.; Eron, Joseph J. (Public Library of Science., 2018)

Abstract available in pdf.
The SAPIT trial provides essential evidence on risks and benefits of integrated and sequential treatment of HIV and tuberculosis.

Abdool Karim, Quarraisha.; Abdool Karim, Salim Safurdeen.; Baxter, Cheryl.; Friedland, Gerald H.; Gengiah, Tanuja N.; Gray, Andrew Lofts.; Grobler, Anna Christina.; Naidoo, Kogieleum.; Padayatchi, Nesri.; El-Sadr, Wafaa. (Health and Medical Publications Group., 2010)

Boulle et al.(1) queried whether a clinical trial was needed to provide the evidence for the mortality benefits of antiretroviral therapy (ART) initiation during tuberculosis (TB) treatment. While several experts, including ...
Scaling up HIV testing in resource-constrained settings: debates on the role of VCT and routine ‘opt-in or opt-out’ HIV testing.

Strode, Ann Elaine.; Van Rooyen, Heidi.; Heywood, Mark.; Abdool Karim, Quarraisha. (South African Medical Association., 2005)

Scaling up of the numbers of people voluntarily undergoing HIV testing has become vital, especially in resource-constrained settings, where the need for knowledge of HIV status for both prevention and care is critical. ...
A scoping review and thematic analysis of social and behavioural research among HIV-serodiscordant couples in high-income settings.

Mendelsohn, Joshua B.; Calzavara, Liviana.; Daftary, Amrita.; Mitra, Sanjana.; Pidutti, Joel.; Allman, Dan.; Bourne, Adam.; Loutfy, Mona.; Myers, Ted. (BioMed Central., 2015)

Abstract available in pdf.
Screening for ‘window-period’ acute HIV infection among pregnant women in rural South Africa.

Kharsany, Ayesha Bibi Mahomed.; Hancock, N.; Fröhlich, Janet Ann.; Abdool Karim, Salim Safurdeen.; Abdool Karim, Quarraisha.; Humphries, Hilton Richard. (Wiley-Blackwell for British HIV Association., 2010)

Objectives. The aim of this study was to evaluate the HIV-1 RNA pooled nucleic acid amplification testing (NAAT) strategy to screen pregnant women in the ‘window period’ of acute HIV infection (AHI) in rural South ...
Secrecy, empowerment and protection : positioning PrEP in KwaZulu-Natal, South Africa.

Govender, Eliza Melissa.; Mansoor, Leila Essop.; MacQueen, Kathleen M.; Abdool Karim, Quarraisha. (Taylor & Francis., 2017)

Abstract available in pdf.
Sensitive tenofovir resistance screening of HIV-1 from the genital and blood compartments of women with breakthrough infections in the CAPRISA 004 tenofovir gel trial.

Wei, Xierong.; Hunt, Gillian.; Abdool Karim, Salim Safurdeen.; Naranbhai, Vivek.; Sibeko, Sengeziwe.; Abdool Karim, Quarraisha.; Li, Jin-fen.; Kashuba, Angela D. M.; Werner, Lise.; Passmore, Jo-Ann Shelley.; Morris, Lynn.; Heneine, Walid.; Johnson, Jeffrey A. (Oxford University Press., 2014)

The Centre for the AIDS Programme of Research in South Africa 004 (CAPRISA 004) study demonstrated that vaginally applied tenofovir gel is a promising intervention for protecting women from sexually acquiring human ...
Sequencing HIV-neutralizing antibody exons and introns reveals detailed aspects of lineage maturation.

Johnson, Erik L.; Doria-Rose, Nicole A.; Gorman, Jason.; Bhiman, Jinal N.; Schramm, Chaim A.; Vu, Ashley Q.; Law, William H.; Zhang, Baoshan.; Bekker, Valerie.; Abdool Karim, Salim Safurdeen.; Ippolito, Gregory C.; Morris, Lynn.; Moore, Penny L.; Kwong, Peter D.; Mascola, John R.; Georgiou, George. (Nature Publishing Group., 2018)

Abstract available in pdf.
Serum glycan-binding IgG antibodies in HIV-1 infection and during the development of broadly neutralizing responses.

Scheepers, Cathrine.; Chowdhury, Sudipa.; Wright, William Shea.; Campbell, Christopher T.; Garrett, Nigel J.; Abdool Karim, Quarraisha.; Abdool Karim, Salim Safurdeen.; Moore, Penny L.; Gildersleeve, Jeffrey C.; Morris, Lynn. (Wolters Kluwer Health., 2017)

Abstract available in pdf.
Shared principles of ethics for infant and young child nutrition in the developing world.

Singh, Jerome Amir.; Daar, Abdallah S.; Singer, Peter A. (BioMed Central., 2010)

Background: The defining event in the area of infant feeding is the aggressive marketing of infant formula in the developing world by transnational companies in the 1970s. This practice shattered the trust of the global ...
Social constraints to TB/HIV healthcare: accounts from coinfected patients in South Africa.

Daftary, Amrita.; Padayatchi, Nesri. (Routledge., 2011)

There is a growing imperative to improve the coordination and collaboration of tuberculosis (TB) and HIV healthcare services in response to escalating rates of TB/HIV coinfection. Patient-specific challenges associated ...
Social context of adherence in an open-label 1% tenofovir gel trial : gender dynamics and disclosure in KwaZulu-Natal, South Africa.

MacQueen, Kathleen M.; Dlamini, Sarah.; Perry, Brian.; Okumu, Eunice.; Sortijas, Steve.; Singh, Chitra.; Pillay, Diantha.; Majors, Alesha.; Jerome, Sonja.; Watson, Sharon.; Abdool Karim, Salim Safurdeen.; Abdool Karim, Quarraisha.; Mansoor, Leila Essop. (Springer., 2016)

Abstract available in PDF file.
South African HIV-1 subtype C transmitted variants with a specific V2 motif show higher dependence on α4β7 for replication.

Richardson, Simone I.; Gray, Elin S.; Mkhize, Nonhlanhla N.; Sheward, Daniel J.; Lambson, Bronwen Elizabeth.; Wibmer, Constantinos Kurt.; Masson, Lindi.; Werner, Lise.; Garrett, Nigel.; Passmore, Jo-Ann Shelley.; Abdool Karim, Quarraisha.; Abdool Karim, Salim Safurdeen.; Williamson, Carolyn.; Moore, Penny L.; Morris, Lynn. (BioMed Central., 2015)

Abstract available in pdf.
Stabilizing HIV prevalence masks high HIV incidence rates amongst rural and urban women in KwaZulu-Natal, South Africa.

Abdool Karim, Quarraisha.; Kharsany, Ayesha Bibi Mahomed.; Fröhlich, Janet Ann.; Werner, Lise.; Mashego, May.; Mlotshwa, Mukelisiwe.; Madlala, Bernadette T.; Ntombela, Fanelesibonge.; Abdool Karim, Salim Safurdeen. (Oxford University Press for the International Epidemiological Association., 2010)

Objective: To determine the HIV incidence rate among rural and urban women in KwaZulu-Natal, South Africa. Methods: We conducted a prospective cohort study from March 2004 to May 2007. Volunteers were recruited from a ...
Stigma impedes AIDS prevention.

Abdool Karim, Salim Safurdeen. (Nature Publishing Group., 2011)

No abstract available.
Strengthening HIV services for pregnant women: an opportunity to reduce maternal mortality rates in Southern Africa/Sub-Saharan Africa.

Moodley, Jagidesa.; Pattinson, R. C.; Baxter, Cheryl.; Sibeko, Sengeziwe.; Abdool Karim, Quarraisha. (Wiley-Blackwell., 2010)

Reliable data from South Africa emanating from WHO recommendations for the Safe Motherhood programme underscores HIV/AIDS as the most common cause of maternal deaths. The strengthening of HIV services for pregnant women ...
Strengthening HIV surveillance in the antiretroviral therapy era: rationale and design of a longitudinal study to monitor HIV prevalence and incidence in the uMgungundlovu District, KwaZulu-Natal, South Africa.

Kharsany, Ayesha Bibi Mahomed.; Cawood, Cherie.; Khanyile, David.; Grobler, Anna Christina.; McKinnon, Lyle R.; Samsunder, Natasha.; Fröhlich, Janet Ann.; Abdool Karim, Quarraisha.; Puren, Adrian.; Welte, Alex.; George, Gavin L.; Govender, Kaymarlin.; Toledo, Carlos.; Chipeta, Zawadi.; Zembe, Lycias.; Glenshaw, Mary T.; Madurai, Lorna.; Deyde, Varough M.; Bere, Alfred. (BioMed Central., 2015)

Abstract available in pdf.

Browsing Caprisa (Centre for the Aids programme of research in South Africa) by Title

Safety and effectiveness of BufferGel and 0.5% PRO 2000 gel for the prevention of HIV infection in women. ﻿

Safety and efficacy of the HVTN 503/Phambili Study of a clade-B-based HIV-1 vaccine in South Africa: a double-blind, randomised, placebo-controlled test-of-concept phase 2b study. ﻿

Safety of tenofovir gel, a vaginal microbicide, in South African women: results of the CAPRISA 004 Trial. ﻿

Safety, tolerability, and pharmacokinetics of long-acting injectable cabotegravir in low-risk HIV-uninfected individuals: HPTN 077, a phase 2a randomized controlled trial. ﻿

The SAPIT trial provides essential evidence on risks and benefits of integrated and sequential treatment of HIV and tuberculosis. ﻿

Scaling up HIV testing in resource-constrained settings: debates on the role of VCT and routine ‘opt-in or opt-out’ HIV testing. ﻿

A scoping review and thematic analysis of social and behavioural research among HIV-serodiscordant couples in high-income settings. ﻿

Screening for ‘window-period’ acute HIV infection among pregnant women in rural South Africa. ﻿

Secrecy, empowerment and protection : positioning PrEP in KwaZulu-Natal, South Africa. ﻿

Sensitive tenofovir resistance screening of HIV-1 from the genital and blood compartments of women with breakthrough infections in the CAPRISA 004 tenofovir gel trial. ﻿

Sequencing HIV-neutralizing antibody exons and introns reveals detailed aspects of lineage maturation. ﻿

Serum glycan-binding IgG antibodies in HIV-1 infection and during the development of broadly neutralizing responses. ﻿

Shared principles of ethics for infant and young child nutrition in the developing world. ﻿

Social constraints to TB/HIV healthcare: accounts from coinfected patients in South Africa. ﻿

Social context of adherence in an open-label 1% tenofovir gel trial : gender dynamics and disclosure in KwaZulu-Natal, South Africa. ﻿

South African HIV-1 subtype C transmitted variants with a specific V2 motif show higher dependence on α4β7 for replication. ﻿

Stabilizing HIV prevalence masks high HIV incidence rates amongst rural and urban women in KwaZulu-Natal, South Africa. ﻿

Stigma impedes AIDS prevention. ﻿

Strengthening HIV services for pregnant women: an opportunity to reduce maternal mortality rates in Southern Africa/Sub-Saharan Africa. ﻿

Strengthening HIV surveillance in the antiretroviral therapy era: rationale and design of a longitudinal study to monitor HIV prevalence and incidence in the uMgungundlovu District, KwaZulu-Natal, South Africa. ﻿

Safety and effectiveness of BufferGel and 0.5% PRO 2000 gel for the prevention of HIV infection in women.

Safety and efficacy of the HVTN 503/Phambili Study of a clade-B-based HIV-1 vaccine in South Africa: a double-blind, randomised, placebo-controlled test-of-concept phase 2b study.

Safety of tenofovir gel, a vaginal microbicide, in South African women: results of the CAPRISA 004 Trial.

Safety, tolerability, and pharmacokinetics of long-acting injectable cabotegravir in low-risk HIV-uninfected individuals: HPTN 077, a phase 2a randomized controlled trial.

The SAPIT trial provides essential evidence on risks and benefits of integrated and sequential treatment of HIV and tuberculosis.

Scaling up HIV testing in resource-constrained settings: debates on the role of VCT and routine ‘opt-in or opt-out’ HIV testing.

A scoping review and thematic analysis of social and behavioural research among HIV-serodiscordant couples in high-income settings.

Screening for ‘window-period’ acute HIV infection among pregnant women in rural South Africa.

Secrecy, empowerment and protection : positioning PrEP in KwaZulu-Natal, South Africa.

Sensitive tenofovir resistance screening of HIV-1 from the genital and blood compartments of women with breakthrough infections in the CAPRISA 004 tenofovir gel trial.

Sequencing HIV-neutralizing antibody exons and introns reveals detailed aspects of lineage maturation.

Serum glycan-binding IgG antibodies in HIV-1 infection and during the development of broadly neutralizing responses.

Shared principles of ethics for infant and young child nutrition in the developing world.

Social constraints to TB/HIV healthcare: accounts from coinfected patients in South Africa.

Social context of adherence in an open-label 1% tenofovir gel trial : gender dynamics and disclosure in KwaZulu-Natal, South Africa.

South African HIV-1 subtype C transmitted variants with a specific V2 motif show higher dependence on α4β7 for replication.

Stabilizing HIV prevalence masks high HIV incidence rates amongst rural and urban women in KwaZulu-Natal, South Africa.

Stigma impedes AIDS prevention.

Strengthening HIV services for pregnant women: an opportunity to reduce maternal mortality rates in Southern Africa/Sub-Saharan Africa.

Strengthening HIV surveillance in the antiretroviral therapy era: rationale and design of a longitudinal study to monitor HIV prevalence and incidence in the uMgungundlovu District, KwaZulu-Natal, South Africa.