Browsing Caprisa (Centre for the Aids programme of research in South Africa) by Title
Now showing items 373-392 of 448
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Safety and effectiveness of BufferGel and 0.5% PRO 2000 gel for the prevention of HIV infection in women.
(Lippincott Williams & Wilkins., 2010)Objective: To determine the safety and effectiveness of BufferGel and 0.5% PRO2000 microbicide gels for the prevention of male-to-female HIV transmission. Design: Phase II/IIb, randomized, placebo-controlled trial with ... -
Safety and efficacy of the HVTN 503/Phambili Study of a clade-B-based HIV-1 vaccine in South Africa: a double-blind, randomised, placebo-controlled test-of-concept phase 2b study.
(Elsevier., 2011)Background. The MRKAd5 HIV-1 gag/pol/nef subtype B vaccine was designed to elicit T-cell-mediated immune responses capable of providing complete or partial protection from HIV-1 infection or a decrease in viral load after ... -
Safety of tenofovir gel, a vaginal microbicide, in South African women: results of the CAPRISA 004 Trial.
(International Medical Press., 2012)Background: Tenofovir gel, used vaginally before and after coitus, reduced women’s acquisition of HIV by 39%. This is a safety assessment of tenofovir gel, including renal, bone, gastrointestinal, genital and haematological ... -
Safety, tolerability, and pharmacokinetics of long-acting injectable cabotegravir in low-risk HIV-uninfected individuals: HPTN 077, a phase 2a randomized controlled trial.
(Public Library of Science., 2018)Abstract available in pdf. -
The SAPIT trial provides essential evidence on risks and benefits of integrated and sequential treatment of HIV and tuberculosis.
(Health and Medical Publications Group., 2010)Boulle et al.(1) queried whether a clinical trial was needed to provide the evidence for the mortality benefits of antiretroviral therapy (ART) initiation during tuberculosis (TB) treatment. While several experts, including ... -
Scaling up HIV testing in resource-constrained settings: debates on the role of VCT and routine ‘opt-in or opt-out’ HIV testing.
(South African Medical Association., 2005)Scaling up of the numbers of people voluntarily undergoing HIV testing has become vital, especially in resource-constrained settings, where the need for knowledge of HIV status for both prevention and care is critical. ... -
A scoping review and thematic analysis of social and behavioural research among HIV-serodiscordant couples in high-income settings.
(BioMed Central., 2015)Abstract available in pdf. -
Screening for ‘window-period’ acute HIV infection among pregnant women in rural South Africa.
(Wiley-Blackwell for British HIV Association., 2010)Objectives. The aim of this study was to evaluate the HIV-1 RNA pooled nucleic acid amplification testing (NAAT) strategy to screen pregnant women in the ‘window period’ of acute HIV infection (AHI) in rural South ... -
Secrecy, empowerment and protection : positioning PrEP in KwaZulu-Natal, South Africa.
(Taylor & Francis., 2017)Abstract available in pdf. -
Sensitive tenofovir resistance screening of HIV-1 from the genital and blood compartments of women with breakthrough infections in the CAPRISA 004 tenofovir gel trial.
(Oxford University Press., 2014)The Centre for the AIDS Programme of Research in South Africa 004 (CAPRISA 004) study demonstrated that vaginally applied tenofovir gel is a promising intervention for protecting women from sexually acquiring human ... -
Sequencing HIV-neutralizing antibody exons and introns reveals detailed aspects of lineage maturation.
(Nature Publishing Group., 2018)Abstract available in pdf. -
Serum glycan-binding IgG antibodies in HIV-1 infection and during the development of broadly neutralizing responses.
(Wolters Kluwer Health., 2017)Abstract available in pdf. -
Shared principles of ethics for infant and young child nutrition in the developing world.
(BioMed Central., 2010)Background: The defining event in the area of infant feeding is the aggressive marketing of infant formula in the developing world by transnational companies in the 1970s. This practice shattered the trust of the global ... -
Social constraints to TB/HIV healthcare: accounts from coinfected patients in South Africa.
(Routledge., 2011)There is a growing imperative to improve the coordination and collaboration of tuberculosis (TB) and HIV healthcare services in response to escalating rates of TB/HIV coinfection. Patient-specific challenges associated ... -
Social context of adherence in an open-label 1% tenofovir gel trial : gender dynamics and disclosure in KwaZulu-Natal, South Africa.
(Springer., 2016)Abstract available in PDF file. -
South African HIV-1 subtype C transmitted variants with a specific V2 motif show higher dependence on α4β7 for replication.
(BioMed Central., 2015)Abstract available in pdf. -
Stabilizing HIV prevalence masks high HIV incidence rates amongst rural and urban women in KwaZulu-Natal, South Africa.
(Oxford University Press for the International Epidemiological Association., 2010)Objective: To determine the HIV incidence rate among rural and urban women in KwaZulu-Natal, South Africa. Methods: We conducted a prospective cohort study from March 2004 to May 2007. Volunteers were recruited from a ... -
Strengthening HIV services for pregnant women: an opportunity to reduce maternal mortality rates in Southern Africa/Sub-Saharan Africa.
(Wiley-Blackwell., 2010)Reliable data from South Africa emanating from WHO recommendations for the Safe Motherhood programme underscores HIV/AIDS as the most common cause of maternal deaths. The strengthening of HIV services for pregnant women ... -
Strengthening HIV surveillance in the antiretroviral therapy era: rationale and design of a longitudinal study to monitor HIV prevalence and incidence in the uMgungundlovu District, KwaZulu-Natal, South Africa.
(BioMed Central., 2015)Abstract available in pdf.