Browsing Caprisa (Centre for the Aids programme of research in South Africa) by Title
Now showing items 294-313 of 448
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Natural killer cell function in women at high risk for HIV acquisition: insights from a microbicide trial.
(Lippincott Williams & Wilkins., 2012)Objective: To assess the role of natural killer (NK) cells in HIV acquisition. Design: We conducted a nested case–control substudy to the Center for the AIDS Programme of Research in South Africa (CAPRISA004) tenofovir gel ... -
The need for multipurpose prevention technologies in sub-Saharan Africa.
(Wiley Online Library., 2014)Abstract available in pdf. -
Nef-mediated down-regulation of CD4 and HLA class I in HIV-1 subtype C infection: association with disease progression and influence of immune pressure.
(Elsevier., 2014)Abstract available in pdf. -
The Neutralization Breadth of HIV-1 Develops Incrementally over Four Years and Is Associated with CD4+ T Cell Decline and High Viral Load during Acute Infection.
(American Society for Microbiology., 2011)An understanding of how broadly neutralizing activity develops in HIV-1-infected individuals is needed to guide vaccine design and immunization strategies. Here we used a large panel of 44 HIV-1 envelope variants (subtypes ... -
Neutralizing antibody responses in acute human immunodeficiency virus type 1 subtype C infection.
(American society for Microbiology., 2007-03-22)The study of the evolution and specificities of neutralizing antibodies during the course of human immunodeficiency virus type 1 (HIV-1) infection may be important in the discovery of possible targets for vaccine design. ... -
New member of the V1V2-directed CAP256-VRC26 lineage that shows increased breadth and exceptional potency.
(American Society for Microbiology., 2016)Abstract available in pdf. -
No evidence for selection of HIV-1 with enhanced gag-protease or nef function among breakthrough infections in the CAPRISA 004 tenofovir microbicide trial.
(2013)Background: Use of antiretroviral-based microbicides for HIV-1 prophylaxis could introduce a transmission barrier that inadvertently facilitates the selection of fitter viral variants among incident infections. To investigate ... -
Non-cationic proteins are associated with HIV neutralizing activity in genital secretions of female sex workers.
(Public Library of Science., 2015)Abstract available in pdf. -
A novel reporter phage to detect tuberculosis and rifampin resistance in a high-HIV-burden population.
(American Society for Microbiology., 2015)Abstract available in pdf. -
Ontogeny-based immunogens for the induction of V2-directed HIV broadly neutralizing antibodies.
(John Wiley & Sons., 2017)Abstract available in pdf. -
Opportunities for treating sexually transmitted infections and reducing HIV risk in rural South Africa.
(Wiley-Blackwell., 2007)Title. Opportunities for treating sexually transmitted infections and reducing HIV risk in rural South Africa Aim. This paper is a report of a study to determine the aetiological distribution of sexually transmitted ... -
Optimal combinations of broadly neutralizing antibodies for prevention and treatment of HIV-1 clade C infection.
(Public Library of Science., 2016)Abstract available in PDF file. -
Optimizing HIV prevention for women: a review of evidence from microbicide studies and considerations for gender-sensitive microbicide introduction.
(International AIDS Society., 2015)Abstract available in pdf. -
Oral and injectable contraceptive use and HIV acquisition risk among women in four African countries : a secondary analysis of data from a microbicide trial.
(Elsevier., 2016)Abstract available in pdf. -
Organ donation, discrimination after death, anti-vaccination sentiments, and tuberculosis management.
(Springer Verlag., 2012)No abstract available. -
Overview of microbicides for the prevention of human immunodeficiency virus.
(Elsevier., 2012)Human immunodeficiency virus (HIV) prevention tools that women can use and control are urgently needed. Microbicides are chemical products applied to the vagina or rectum to prevent the sexual transmission of HIV. Four ... -
Patients’ readiness to start highly active antiretroviral treatment for HIV.
(BMJ publishing group., 2005)Assessing whether patients are ready to start antiretroviral treatment may improve HIV prevention and treatment outcomes. -
Phase I safety and immunogenicity evaluations of an alphavirus replicon HIV-1 subtype C gag vaccine in healthy HIV-1-uninfected adults.
(American Society for Microbiology., 2012)On the basis of positive preclinical data, we evaluated the safety and immunogenicity of an alphavirus replicon HIV-1 subtype C gag vaccine (AVX101), expressing a nonmyristoylated form of Gag, in two double-blind, randomized, ... -
Pilot evaluation of a second-generation electronic pill box for adherence to Bedaquiline and antiretroviral therapy in drug-resistant TB/HIV co-infected patients in KwaZulu-Natal, South Africa.
(BioMed Central., 2018)Abstract available in pdf. -
A pilot study of once-daily antiretroviral therapy integrated with Tuberculosis directly observed therapy in a resource-limited setting.
(Lippincott Williams & Wilkins., 2003)To determine the feasibility and effectiveness of integrating highly active antiretroviral therapy (HAART) into existing tuberculosis directly observed therapy (TB/DOT) programs, we performed a pilot study in an urban ...