Browsing Caprisa (Centre for the Aids programme of research in South Africa) by Title
Now showing items 262-281 of 448
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Key issues in the clinical development and implementation of TB vaccines in South Africa.
(Elsevier., 2012)Significant progress has been made in advancing the development pipeline for a new and more effective TB vaccine with some candidate vaccines now in late stage clinical evaluation. However, progress has been hampered ... -
Killer-cell Immunoglobulin-like Receptor (KIR) gene profiles modify HIV disease course, not HIV acquisition in South African women.
(BioMed Central., 2016)Abstract available in PDF file. -
Killer-cell immunoglobulin-like receptor genotyping and HLA killer-cell immunoglobulin-like receptor-ligand identification by real-time polymerase chain reaction.
(John Wiley & Sons., 2011)The effector function of natural killer (NK) cells is modulated by surface expression of a range of killer-cell immunoglobulin-like receptors (KIRs) that interact with human leukocyte antigen (HLA) class I ligands. We ... -
Knowledge and acceptability of HAART among TB patients in Durban, South Africa.
(Taylor & Francis., 2005)From October 2002 to February 2003, we conducted semi-structured interviews on knowledge of HIV, antiretroviral treatment, and willingness to participate in voluntary counselling and testing and HAART with 54 consenting ... -
Lessons from a randomised clinical trial for multidrug-resistant tuberculosis.
(International Union against Tuberculosis and Lung Disease., 2012)BACKGROUND: The treatment of multidrug-resistant tuberculosis (MDR-TB) is currently based upon expert opinion and findings from case series, rather than upon randomised clinical trials (RCTs). OBJECTIVE: To describe the ... -
Limited HIV-1 superinfection in seroconverters from the CAPRISA 004 Microbicide trial.
(American Society for Microbiology., 2014)HIV-1 superinfection (SI) occurs when an infected individual acquires a distinct new viral strain. The rate of superinfection may be reflective of the underlying HIV risk in a population. The Centre for the AIDS Programme ... -
Limited Neutralizing Antibody Specificities Drive Neutralization Escape in Early HIV-1 Subtype C Infection.
(Plos, 2009)We previously showed that HIV-1 subtype C viruses elicit potent but highly type-specific neutralizing antibodies (nAb) within the first year of infection. In order to determine the specificity and evolution of these ... -
Low adverse event rates following voluntary medical male circumcision in a high HIV disease burden public sector prevention programme in South Africa.
(International AIDS Society., 2014)Introduction: The provision of voluntary medical male circumcision (VMMC) services was piloted in three public sector facilities in a high HIV disease burden, low circumcision rate province in South Africa to inform policy ... -
Low rifampicin concentrations in tuberculosis patients with HIV infection.
(Open Learning on Enteric Pathogens., 2014)Abstract available in pdf. -
Lower concentrations of chemotactic cytokines and soluble innate factors in the lower female genital tract associated with the use of injectable hormonal contraceptive.
(Elsevier., 2015)Abstract available in pdf. -
Managing multiple and extensively drug-resistant tuberculosis and HIV.
(Informa Healthcare., 2007)Global increases in multi-drug-resistant and extensively drug-resistant tuberculosis (TB), are threatening both TB and HIV treatment programs worldwide. Together, they raise concerns of a global epidemic of untreatable TB. ... -
Mannose-rich glycosylation patterns on HIV-1 subtype C gp120 and sensitivity to the lectins, Griffithsin, Cyanovirin-N and Scytovirin.
(Elsevier., 2010)Griffithsin (GRFT), Cyanovirin-N (CV-N) and Scytovirin (SVN) are lectins that inhibit HIV-1 infection by binding to multiple mannose-rich glycans on the HIV-1 envelope glycoproteins (Env). Here we show that these lectins ... -
Mapping polyclonal HIV-1 antibody responses via next-generation neutralization fingerprinting.
(Public Library of Science., 2017)Abstract available in pdf. -
MDR-TB patients in KwaZulu-Natal, South Africa: cost-effectiveness of 5 models of care.
(Public Library of Science., 2018)Abstract available in pdf. -
Measuring adherence by visual inspection of returned empty gel applicators in the CAPRISA 004 microbicide trial.
(Springer., 2014)Abstract not available in pdf. -
Medical education after the first decade of democracy in South Africa.
(Elsevier., 2004)No abstract available. -
Meeting the sexual and reproductive health needs of high-school students in South Africa: experiences from rural KwaZulu-Natal.
(South African Medical Association., 2014)Abstract available in pdf. -
Microbial translocation and microbiome dsybiosis in HIV-associated immune activation.
(Wolters Kluwer., 2016)Abstract available in pdf. -
Microbicide clinical trial adherence: insights for introduction.
(BioMed Central., 2012)After two decades of microbicide clinical trials it remains uncertain if vaginally- delivered products will be clearly shown to reduce the risk of HIV infection in women and girls. Furthermore, a microbicide product with ... -
Microbicides & their implications in HIV prevention.
(MedKnow Publications., 2010)No abstract available.