Browsing Caprisa (Centre for the Aids programme of research in South Africa) by Title
Now showing items 55-74 of 448
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The C3-V4 region is a major target of autologous neutralizing antibodies in human immunodeficiency virus type 1 subtype C Infection.
(American Society for Microbiology., 2008)The early autologous neutralizing antibody response in human immunodeficiency virus type 1 (HIV-1) subtype C infections is often characterized by high titers, but the response is type specific with little to no cross-neutralizing ... -
CAPRISA 004 tenofovir microbicide trial: no impact of tenofovir gel on the HIV transmission bottleneck.
(Oxford University Press., 2011)Alterations of the genital mucosal barrier may influence the number of viruses transmitted from a human immunodeficiency virus–infected source host to the newly infected individual. We used heteroduplex tracking assay and ... -
Case 15-2011: A 19-year-old South African woman with headache, fatigue, and vaginal discharge.
(Massachusetts Medical Society., 2011)No abstract available. -
Case report: mechanisms of HIV elite control in two African women.
(BioMed Central., 2018)Abstract available in pdf. -
Case series of the long-term psychosocial impact of drug-resistant tuberculosis in HIV-negative medical doctors.
(International Union against Tuberculosis and Lung Disease., 2010)BACKGROUND: Health care workers (HCWs) are at greater risk for tuberculosis (TB), including multidrug-resistant TB (MDR-TB), compared to the general population. The psychosocial impact of nosocomial TB on HCWs has received ... -
CCR5 expression, haplotype and immune activation in protection from infection in HIV‐exposed uninfected individuals in HIV serodiscordant relationships.
(John Wiley & Sons., 2017)Abstract available in pdf. -
CD8+ T cell breadth and ex vivo virus inhibition capacity distinguish between viremic controllers with and without protective HLA class I alleles.
(American Society for Microbiology., 2016)Abstract available in PDF file. -
Cervicovaginal inflammation facilitates acquisition of less infectious HIV variants.
(Oxford University Press., 2017)Abstract available in pdf. -
The challenge of discharging research ethics duties in resource-constrained settings.
(Plos, 2011)No abstract available. -
Challenges in HIV-prevention microbicide research.
(American Association for the Advancement of Science., 2008)No abstract available. -
Challenges of diagnosing acute HIV-1 subtype C infection in African women: performance of a clinical algorithm and the need for point-of-care nucleic-acid based testing.
(Plos., 2012)Background. Prompt diagnosis of acute HIV infection (AHI) benefits the individual and provides opportunities for public health intervention. The aim of this study was to describe most common signs and symptoms of AHI, ... -
Challenging racial stereotyping of AIDS in South Africa with prevalence of HIV in pregnant women.
(South African Medical Association / Health & Medical Publications Group., 2007)No abstract available. -
Changes in natural killer cell activation and function during primary HIV-1 infection.
(Plos., 2012)Background. Recent reports suggest that Natural Killer (NK) cells may modulate pathogenesis of primary HIV-1 infection. However, HIV dysregulates NK-cell responses. We dissected this bi-directional relationship to understand ... -
Changes to antiretroviral drug regimens during integrated TB-HIV treatment: results of the SAPiT trial.
(International Medical Press., 2014)Background—Frequency of drug changes in combination antiretroviral therapy among patients starting both tuberculosis (TB) and human immunodeficiency virus (HIV) therapy, as a result of treatment-limiting toxicity or ... -
The changing epidemiology of HIV in 2013.
(Lippincott Williams & Wilkins., 2013)Purpose of review. We sought to review the recent epidemiology of HIV-1 and to identify emerging challenges in HIV surveillance and epidemic control. Recent findings. There is increasing evidence that HIV epidemics are ... -
Characteristics of women enrolled into a randomized clinical trial of dapivirine vaginal ring for HIV-1 prevention.
(Public Library of Science., 2015)Abstract available in pdf. -
Characterization of anti-HIV-1 neutralizing and binding antibodies in chronic HIV-1 subtype C infection.
(Elsevier., 2012)Neutralizing (nAbs) and high affinity binding antibodies may be critical for an efficacious HIV-1 vaccine. We characterized virus-specific nAbs and binding antibody responses over 21 months in eight HIV-1 subtype C chronically ... -
Characterization of nucleoside reverse transcriptase inhibitor-associated mutations in the RNAse H region of HIV-1 subtype c infected individuals.
(Viruses., 2017)Abstract available in pdf. -
Chest radiograph findings and time to culture conversion in patients with multidrug-resistant tuberculosis and HIV in Tugela Ferry, South Africa.
(Plos., 2013)Background: The majority of patients with multidrug-resistant tuberculosis (MDR-TB) in South Africa are co-infected with HIV, but the radiographic features of MDR-TB and their relationship with time to sputum culture ...