Masters Degrees (Physiology)
Recent Submissions
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Investigating the effects of diet-induced pre-diabetes on calcium homeostasis in male Sprague Dawley rats.
(2022)Diabetes mellitus (DM) affects over 400 million people worldwide with 90-95% being type 2 diabetes mellitus (T2DM) in South Africa. T2DM is positively correlated with the chronic consumption of a high caloric diet, often ... -
The alteration of dopamine receptors in L-DOPA (L-3,4-dihydroxyphenylalanine) induced dyskinesias.
(2021)L-3,4-dihydroxyphenylalanine (L-DOPA) can ease symptoms of Parkinson’s disease (PD), butextended use of L-DOPA causes abnormal involuntary movements (AIMs) called L-DOPA induced dyskinesias (LIDs). The present study aims ... -
Biomarkers and histopathologic changes in rats with monocrotaline-induced pulmonary hypertension following administration of antiretroviral medications.
(2020)Pulmonary hypertension (PH) is a progressive life-threatening vasculopathy characterized by dysregulated pulmonary vascular remodelling that results in an increased pulmonary vascular resistance, right ventricular ... -
The determination of unilateral ratios (knee and shoulder muscle strength), of provincial cricketers.
(2002)Abstract available in PDF. -
The effect of infra-red laser therapy on fibroblast activity in cell culture.
(1997)Abstract available in PDF. -
The use of laser doppler fluxmetry in the pre-operative assessment of amputation wound healing in the dysvascular patient.
(1997)Abstract available in PDF. -
Evaluating the role of maternal separation stress on the development of autistic-like behaviour in Sprague-Dawley rats.
(2020)Autism Spectrum Disorders (ASD) are a category of neurodevelopmental disorders that have become more prevalent, causing much concern. Autistic individuals display symptoms ranging from repetitive behaviours to communication ... -
Effects of antipsychotic dose reduction on metabolic syndrome in patients with first episode psychosis treated with a long-acting injectable antipsychotic.
(2019)Background: The introduction of antipsychotics has been a significant milestone in the treatment of schizophrenia. However, these agents have several important side effects, such as metabolic syndrome. Options to curb these ... -
Effects of momordica balsamina on glucose handling in high fat high carbohydrate induced prediabetic rat model and glucose handling in C2C12 induced insulin resistant cell lines: effects on selected metabolic markers.
(2020)Increased consumption of fat and high carbohydrate coincided with increased prevalence in type 2 diabetes, a condition whose onset is always preceded by prediabetes. Prediabetes is best characterised by hyperglycaemia, ... -
The effects of prenatal stress on the preoptic nuclei of febrile seizure rat models.
(2019)Febrile seizures are a neurological abnormality that occurs after an underlying systemic infection, leading to fever and followed by convulsions due to neuronal hyper-excitability. Although regarded as benign, prenatal ... -
Effects of Momordica balsamina methanolic extract on cardiovascular and haematological function in streptozotocin-induced diabetic rats : effects on selected markers.
(2018)Background The hyperglycaemia-induced haemanetic changes reduces the oxygen-carrying capacity of erythrocytes, thus aggravating cardiovascular disorders in diabetic patients. The conventional therapies have been shown to ... -
Investigating changes to the insulin signalling pathway in a diet-induced pre-diabetic rat model: effects on selected markers.
(2019)No abstract available. -
A voice-centered relational analysis of the career development narratives of six Black African professionals in KwaZulu-Natal, South Africa.
(2018)Career Psychology and career education is not a new concept in the South African context, it is evident dating back as far as 1943. Literature shows that career guidance was first introduced in White schools and later ... -
HIV-1 transactivator of transcription (TAT) protein causes neurotoxicity via astrocyte activation.
(2015)HIV is most well-known for its negative effects on the immune system and the resulting development of AIDS, however it also has severe damaging effects on the central nervous system. Many infected individuals exhibit ... -
Prenatal stress and febrile seizures effects on the epigenetic mechanisms involved in cognitive function following treatment with Searsia chirindensis.
(2016)Febrile seizures are of growing concern in the health fraternity within the African continent. These seizures predominantly affect children between the ages of 3 months and 5 years of age. Stress during pregnancy may ... -
The efficacy of manual versus local vibratory massage in promoting recovery from post-exercise muscle damage - a systematic review.
(2016)Background. It is well established that unaccustomed activity/exercise with a large eccentric component causes the development of muscle damage which results in soreness and a decline in the functional capacity of muscle. ... -
Evaluation of the efficacy of maslinic acid on malaria parasites in Plasmodium berghei-infected male Sprague-Dawley rats : effects on blood glucose and renal fluid and electrolyte handling.
(2014)Introduction Malaria remains a major socio-economic burden in Africa despite the numerous global efforts to control and manage the disease through prevention and drug intervention. Clinical studies have shown that malaria ... -
Effect of highly active antiretroviral therapy (HAART) on HIV-1 tat protein-induced neurotoxicity.
(2014)Background: HIV-1-trans-activating (Tat) protein has been associated with development of HIV associated neurocognitive disorder (HAND). Previous studies have demonstrated that Tat protein causes neurotoxicity through an ...
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