Browsing Biochemistry by Issue Date
Now showing items 1-20 of 191
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Some aspects of the role of rat liver ribosomes in protein biosynthesis.
(1969)No abstract available. -
Studies on the structural and biological functions of the Cu3 and Cu4 domains of IgM.
(1977)No abstract available. -
Assessment of lysine damage during food processing.
(1985)The fluorodinitrobenzene (FONB), succinic anhydride (SA), dansyl chloride (DAN), dye-binding lysine (OBL), total lysine (TL), ninhydrin (NIN) and Tetrahymena lysine (TET) methods were compared for their ability to ... -
The occurrence of mycotoxins in feedstuffs in Natal and aspects of their metabolism in the rumen.
(1985)The fluorodinitrobenzene (FONB), succinic anhydride (SA), dansyl chloride (DAN), dye-binding lysine (OBL), total lysine (TL), ninhydrin (NIN) and Tetrahymena lysine (TET) methods were compared for their ability to ... -
Canine anti-endotoxin immunotherapy in cranial mesenteric arterial occlusion shock and canine parvovirus disease endotoxaemia.
(1986)Endotoxin (LPS, lipopolysaccharide) forms an integral part of the outer cellular membrane of gram negative bacteria (GNB). The canines' intestine always contains large amounts of GNB, and hence LPS. If these GNB with ... -
Synthesis of DNA - protein conjugates and a preliminary study of their interaction with eukaryotic cell receptors.
(1986)Thymidine oligomers were chemically synthesised and linked to available amino functions of transferrin in alternative orientations: (a) A CMP residue attached to the 3' end of (pT)₁₀ with terminal deoxynucleotidyl transferase ... -
Studies on the preparation and interaction of modified transferrin-DNA complexes with HeLa cells.
(1986)The correction of human genetic disorders by transfer of genetic material to cells is under intensive investigation in a number of 1aboratories. One possible way of trying to achieve the transfer of nucleic acid is ... -
Preparation of chemically modified transferrin proteins and an investigation of their reactions with DNA and other nucleic acids.
(1986)The molecular biology of human genetic disorders is under intensive investigation at present. In those cases where the disorder is clearly defined in terms of altered gene structure, possibilities may exist for the correction ... -
Studies on the coupling of DNA to low density lipoproteins (LDL) and the interaction of these complexes with eukaryotic cells.
(1987)The application of Molecular Biochemistry for transfection studies in eukaryotic systems is well documented. Of the numerous methods employed for the introduction of foreign DNA into eukaryotic cells, the use of low ... -
A study of the proteinase, cathepsin L, in the context of tumour invasion.
(1990)The proteinase, cathepsin L, has been strongly implicated in the processes of tumour invasion and metastasis. A new purification method, three-phase partitioning, characterised in terms of the parameters which affected its ... -
The development of assays for atractyloside and its localisation in rat tissue.
(1991)An extract of the tuber of Callilepis laureola is regarded as the source of a powerful therapeutic agent, known as Impila. Its use is associated with fatal hepatic and renal necrosis, the renal toxin being atractyloside ... -
Type IV collagenase and cathepsins L and H : proteinases involved in tumour invasion.
(1992)The collagenolytic proteinases, type IV collagenase and cathepsins Land H, have been implicated in tumour invasion and metastasis, by virtue of their degradative action on the extracellular matrix barriers traversed by ... -
A study of proteinases of invasive cells using cryoultramicrotomy and immunogold labelling.
(1993)This study forms part of an investigation into the possible relevance of the lysosomal proteinases, cathepsins B, H, Land D, in cancer cell invasion. In this study, the main technique adopted was the Tokuyasu "cryo" ... -
Making sense of mixtures : chromatographic separations of plant, insect and microbial biomolecules.
(1996)No abstract available. -
Trypanopain : a possible target for anti-trypanosomal agents?
(1997)The protozoan parasite Trypanosoma brucei brucei causes nagana in cattle and is a widely used model for human sleeping sickness. The major lysosomal cysteine proteinases (trypanopains) of African trypanosomes may contribute ... -
Coupling dyes to chicken IgY antibodies for the development of immunodiagnostic tests.
(2003)The aim of this study was to develop a highly simplified, sensitive and specific malarial diagnostic test at the lowest possible cost. Initial work and optimisation of procedures was achieved with chicken antibodies by ... -
Cloning and recombinant expression of a 822 bp region of a Pf403 Plasmodium falciparum gene.
(2003)Malaria is a devastating parasitic disease in humans caused by species in the genus Plasmodium. With over 100 million cases and at least 1.5 million fatalities each year, the disease accounts for 4-5% of all fatalities ...