Now showing items 1-9 of 9
Biochemical studies on trypanosomal prolyl oligopeptidase family pathogenic factors.
African Animal trypanosomosis, also known as Nagana, is a parasitic disease which affects many mammalian species, mainly livestock such as cattle, sheep and goats. The disease also affects humans (Human African Trypanosomosis) ...
Recombinant expression, purification and characterisation of TviCATL for antibody production and diagnosis of African animal Trypanosomiasis.
For the effective control of African animal trypanosomiasis, there is a great need for the development of point of care diagnostic tests that are affordable to the end-users. Parasite cysteine proteases are involved in the ...
Novel epidermal growth factor directed cationic lipoplexes promote in vitro hepatotropic gene targeting.
The need for the improvement in protocols for cellular gene delivery has propelled cytofectin based liposomes as suitable non-viral gene carriers. The amenability of cationic liposomes to modification enables research based ...
Investigation into the major surface proteases of African trypanosomes.
The unicellular parasite of the genus Trypanosoma infects a number of mammalian species including livestock and humans. In sub-Saharan Africa three main parasitic species cause disease: Trypanosoma brucei, T. congolense ...
Extracellular matrix factors influence myoblast activation, differentiation and fusion.
Satellite cells are muscle stem cells that reside in a niche between the basal lamina and sarcolemma of mature muscle fibers. Upon muscle injury, these cells are activated to myoblasts that subsequently proliferate, ...
An in vitro assessment of functionalized gold nanoparticles in anticancer drug delivery.
Abstract available in PDF file.
The use of cholesterol-galacto compounds in liver directed gene delivery.
Gene therapy has to date gained immense interest as a potential method for treating genetic disorders such as Parkinson’s and cystic fibrosis. The liver being a central organ of metabolism is susceptible to several ...
Effects of oleanolic acid on small intestine morphology and enzymes of glutamine metabolism in diabetic rats.
The small intestine (SI) is the main site for food absorption and glutamine utilization hence critical in metabolic disorders that involve energy balance such as diabetes and obesity. This study aims to assess the effects ...
Biosystematic studies in Southern African species of Strychnos L. (Loganiaceae)
Strychnos L. is the largest genus of the pantropical or subtropical family Loganiaceae with about 200 species. Their habits range from trees and shrubs in open areas to lianas in rain forests. The genus is well-known as ...