Now showing items 41-50 of 136
A contribution to the biochemistry of Erwinia chrysanthemi.
No abstract available.
Identification and characterisation of novel pathogenic factors of Trypanosoma congolense.
Trypanosoma congolense is a major causative agent of the bovine disease trypanosomosis which has a considerable economic impact on sub-Saharan Africa. Current control methods for trypanosomosis are unsatisfactory and ...
The study of the impact of selected mutations in FMS-like Tyrosine Kinase III (FLT3) and Nucleophosmin (NPM1) - and HIV status on patients with acute Myeloid Leukemia and their response to induction therapy.
Acute Myeloid Leukemia (AML), the most common form of acute leukemia in adults, is only curable in approximately 30% of all cases. Despite prognostic risk stratification using sub-typing and cytogenetic analysis to direct ...
Induction of auto-antibodies to Cathepsin B.
Because tumours are comprised of "self" cells and antigens, they escape recognition by the immune system, which discriminates between "self" and "non-self". One such antigen is cathepsin B, a lysosomal cysteine proteinase, ...
Studying trypanosomal peptidase antigen targets for the diagnosis of animal African trypanosomiasis.
The lack of a vaccine candidate due to antigenic variation by trypanosomal parasites, the causative agents of human and animal African trypanosomiasis, requires the disease to be controlled by surveillance, diagnosis and ...
The biochemistry and medical aspects of naturally occurring toxins.
The work presented here represents research done on mycotoxins and plant toxins by the author and his postgraduate students over a period from 1964 to date. The first phase, which ends at 1980, mainly addresses the ...
Fructose-fed streptozotocin-injected rat : an alternative model for type 2 diabetes.
The principal objective of this study was to develop an alternative non-genetic rat model for type 2 diabetes (T2D). Six-week-old male Sprague-Dawley rats (190.56 ± 23.60g) were randomly divided into six groups namely: ...
A study of the African horse sickness virus using High Resolution Melt, multivariate and phylogenetic analyses for a potential serotyping assay.
African horse sickness (AHS) is a viral disease that afflicts all equine species and has a 90% mortality rate in unvaccinated horses. The disease has a devastating effect on the national herd of South Africa each year ...
Effect of nitrate upon the digestibility of kikuyu grass (Pennisetum clandestinum)
The factors affecting the accumulation of nitrate in kikuyu grass pastures and the effect of elevated nitrate levels upon digestion in the ruminant were investigated. A high potassium level in the soil seems to be the ...