Now showing items 1-4 of 4
Membrane type I metalloproteinase (mt1-mmp) as a target in cancer : a study of two inhibitors.
Several diseases, including cancer, have been associated with high membrane type-1 matrix metalloproteinase (MT1-MMP) expression levels. MT1-MMP together with a non-membrane-bound, soluble MMP, MMP-2, also associated with ...
Effect of c-Ha-ras(V12) on protease trafficking in invasive breast cancer cells.
Effect of c-Ha-ras(V12) on cathepsin trafficking in invasive breast cancer cells. Various mutations of Ha-ras together with lack of p53-related control over cell cycle progression, result in an immortal, tumorigenic ...
Proteinases and extracellular matrix degradation in breast cancer.
A variety of proteases have been shown to promote the progression of cancer by virtue of their ability to degrade extracellular proteinaceous barriers, such as basement membrane and interstitial stroma. At the outset of ...
Assessment of hypoxoside and its derivatives as anti-cancer drugs.
Extracts of the African potato have long been believed to have anti-cancer properties. The aim of the current research was to isolate hypoxoside (HYP) from Hypoxis hemerocallidea (African potato) and synthesize ...