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The in vitro and in vivo anti-oxidative and anti-diabetic effects of some African medicinal plants and the identification of the bioactive compounds.
This thesis examined the in vitro and in vivo anti-oxidative and anti-diabetic activities of five African medicinal plants which are traditionally used for the treatment of diabetes mellitus viz; Ziziphus mucronata, Cassia ...
Studies on the possible mechanisms behind the anti-diabetic effects of Xylitol.
Background and Objectives: Sugar substitutes have gained popularity in the management of diabetes, obesity and related diseases, due to their low calorie content compared to sucrose. Recent studies have reported that ...
Development of an alternative non-obese non-genetic rat model of type 2 diabetes using caffeine and streptozotocin.
The aim of the present study was to develop an alternative non-obese non-genetic rat model of type 2 diabetes (T2D). Six-week-old male Sprague-Dawley rats were randomly divided into six groups, namely: Normal Control (NC), ...
Fructose-fed streptozotocin-injected rat : an alternative model for type 2 diabetes.
The principal objective of this study was to develop an alternative non-genetic rat model for type 2 diabetes (T2D). Six-week-old male Sprague-Dawley rats (190.56 ± 23.60g) were randomly divided into six groups namely: ...
Investigation of anti-diabetic properties of Psidium guajava leaf in streptozocin induced diabetic rats.
Diabetes mellitus results in chronic hyperglycaemia, leading to defects in carbohydrate, fat and protein metabolism. Diabetes mellitus is also linked with elevated plasma cholesterol and triglyceride levels, which may ...
The measurement of glomerular basement membrane components and glycated albumin as improved markers of incipient diabetic nephropathy.
Diabetes causes early structural changes to the glomerular basement membrane (GBM), which alters its function and leads to loss of protein in urine. Formation of advanced glycation endproducts (AGEs) is one mechanism ...