Paediatrics and Child Health
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Outcomes of elective surgical patients admitted to a tertiary Paediatric Intensive Care Unit.
(2021)Background: A paediatric intensive care unit (PICU) is a unit for critically ill medical and surgical children. It is imperative that the spectrum and outcome of elective surgical patients is reviewed to help develop ... -
Evaluation of an exclusive breastfeeding promotion programme in an informal settlement in Durban.
(2002)Abstract available in PDF. -
The antibody response to different measles vaccine strains given by the aerosol and subcutaneous routes to schoolchildren.
(2003)Abstract available in PDF. -
Stress, resources and coping processes in chronic childhood illness.
(1994)Abstract available in PDF. -
The role of immunoregulatory cells in healthy and sick African children.
(1987)Abstract available in PDF. -
Studies on the mechanisms of proteinuria in kidney diseases of childhood.
(1994)Abstract available in PDF. -
Validation of bioimpedance against isotope methods for the determination of body composition in HIV infected South African children.
(2010)Abstract available in PDF. -
The role of parenteral phenobarbitone in the treatment of neonatal hyperbilirubinaemia.
(1993)Abstract available in PDF. -
Assessing reported adherence to antiretroviral therapy using the method of verbal recall in children from Kwa-Zulu Natal, South Africa.
(2017)Sub-Saharan Africa has the highest number of children living with HIV. HIV is one of the major causes of under-five mortality in Africa. Antiretroviral therapy in the paediatric population has improved mortality, led to a ... -
Severe acute malnutrition and antiretroviral treatment in children with HIV.
(2016)Background: Childhood malnutrition remains a common problem in many parts of the world and is a contributing factor in 45% of the 5.9 million annual deaths in children under 5 years. HIV-infected children have a ... -
Comparison of virological responses of children commenced on an abacavir versus stavudine based antiretroviral regimen at King Edward VIII Hospital : Durban.
(2016)Background: UNAIDS estimated that in 2014 just over 160 000 children in South Africa were receiving HAART, accounting for 20% of the global HAART cohort. Finding the appropriate HAART regimen that is safe, well tolerated ... -
The accuracy, sensitivity and specificity of rapid point-of-care testing for CD4+ T cell count enumeration and TB diagnosis.
(2014)Objectives: The PIMA CD4+ T cell count analyser has been favourably evaluated for use in point-of-care (POC) situations in Mozambique and Zimbabwe, has also been recommended by the World Health Organisation (WHO), however, ... -
Hepatitis B virus-associated membranous nephropathy.
(2002)Glomerulonephritis as an extra hepatic manifestation of chronic HBV infection has now been well documented [1,2,3,4,5]. HBV-associated nephropathy has been described in areas of both high and low endemicity [6]. In Africa ... -
Innate immune mechanisms in limiting HIV-1 pathogenesis among South African adults and mother-infant pairs.
(2012)This study was conducted to investigate the role of natural killer cell surface receptors, KIRs and their cognate HLA ligands in preventing HIV-1 acquisition and disease progression in HIV-1 exposed infants. Using DBS ... -
Cellular immunity, immune activation and regulation in HIV-1 infected mother-child pairs : what are the determinants of protective immunity.
(2011)Background: Prevention of Mother-to-child transmission (PMTCT) of human immunodeficiency virus (HIV) remains a significant challenge in resource-poor settings despite the advances in antiretroviral (ARV) treatment. HIV-1 ... -
The association of early neonatal feeding on clinical outcomes and cytotoxic T lymphocyte (CTL) responses in HIV exposed low birth weight infants.
(2011)BACKGROUND Sub-saharan Africa remains to date at the forefront of the HIV/AIDS epidemic. Despite breastfeeding being a significant mode of postnatal HIV transmission it remains the main nutritional source and pillar of ... -
The role of HLA-C restricted CD8+T cell responses in the control of HIV replication.
(2010)Certain HLA-B-restricted CD8+ T cell responses are associated with control of viremia whereas HLA-Cw* restricted responses, including Gag epitopes are associated with high viremia. To better understand the role of ... -
Coreceptor utilization and primary cell tropism by HIV-1 subtype C strains.
(2010)Human immunodeficiency virus type 1 (HIV-1) isolates can be differentiated based on their ability to use particular coreceptors – R5 viruses use CCR5, X4 viruses use CXCR4 and R5X4 (dual tropic) viruses use both CCR5 ... -
Is IMCI an effective mechanism for delivery of child survival interventions in a high HIV prevalence setting? : a study to determine the effectiveness of the Intergrated Management of Childhood Illness (IMCI) strategy in management of sick children in routine practise in primary health care clinics in South Africa
(2012)Introduction: Integrated management of childhood illness (IMCI) is a child survival strategy that has been adopted in South Africa (SA) as the standard of care for managing sick children in the primary health care setting. ...
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