Now showing items 1-2 of 2
The role of the protease cleavage sites in viral fitness and drug resistance in HIV-1 subtype C.
There is an increasing number of patients failing second line highly active antiretroviral therapy (AZT, DDI and LPV/r) in South Africa, where HIV-1 subtype C predominates. Mutations at gag cleavage sites (CS) have ...
Cellular and biochemical effects induced by antiretroviral drugs.
In the treatment of HIV/AIDS, protease inhibitors (PIs) and nucleoside/nucleotide analogue reverse transcriptase inhibitors (NRTIs) are the major components of highly active antiretroviral therapy (HAART). The side effects ...