Now showing items 1-3 of 3
Effect of highly active antiretroviral therapy (HAART) on HIV-1 tat protein-induced neurotoxicity.
Background: HIV-1-trans-activating (Tat) protein has been associated with development of HIVassociated neurocognitive disorder (HAND). Previous studies have demonstrated that Tat protein causes neurotoxicity through an ...
A biochemical assessment of stress response following acute and prolonged exposure to antiretroviral drugs (nucleoside reverse transcriptase inhibitors) in vitro.
Nucleoside reverse transcriptase inhibitors (NRTIs) are the most extensively used antiretroviral (ARV) drugs in highly active antiretroviral therapy (HAART). The long term use of HAART is associated with changes to metabolic ...
Cellular and biochemical effects induced by antiretroviral drugs.
In the treatment of HIV/AIDS, protease inhibitors (PIs) and nucleoside/nucleotide analogue reverse transcriptase inhibitors (NRTIs) are the major components of highly active antiretroviral therapy (HAART). The side effects ...