Now showing items 1-10 of 25
The use of machine learning to improve the effectiveness of ANRS in predicting HIV drug resistance.
BACKGROUD HIV has placed a large burden of disease in developing countries. HIV drug resistance is inevitable due to selective pressure. Computer algorithms have been proven to help in determining optimal treatment for ...
Extrapulmonary tuberculosis at King Edward hospital : a descriptive retrospective study.
Background Globally, South Africa remains one of the top twenty high tuberculosis(TB) burden countries. In addition, South Africa has the highest burden of tuberculosis/Human Immunodeficiency virus (TB/HIV) coinfection in ...
The effect of genital tract inflammation on HIV-specific binding antibodies, IgG subclass and Isotype transudation.
Abstract available in PDF file.
Assessing reported adherence to antiretroviral therapy using the method of verbal recall in children from Kwa-Zulu Natal, South Africa.
Sub-Saharan Africa has the highest number of children living with HIV. HIV is one of the major causes of under-five mortality in Africa. Antiretroviral therapy in the paediatric population has improved mortality, led to a ...
The relationship between child rearing practices and adolescents’ attitudes toward sexual debut, Durban, South Africa.
About 30% of South African teenagers between the ages of 13-19 years have reported unplanned pregnancy in their lives. One of the determinants of the teenage pregnancy and HIV is early sexual debut. Adolescents who engage ...
Expression of plasma nuclear factor KAPPA-B (NFκB) and inhibitory subunit KAPPA B ALPHA (IκB-α) in HIV-associated pre-eclamsia.
Objective: The relationship between pre-eclampsia and HIV-1 infection is one of the most unexplored relationships in research. Pre-eclampsia is characterized by inflammation and HIV is characterized by a decline in immune ...
The role of c-jun n-terminal kinase (JNK) and tumour protein (p53) in HIV associated pre-eclampsia.
Background: In pre-eclampsia, immune maladaptation to the foetal allograft results in impaired trophoblast invasion and defective spiral arterial remodelling with consequential placental oxidative stress. Placental apoptosis ...
Prevalence, risk factors and pregnancy outcomes of cervical cell abnormalities in the puerperium in a hyperendemic HIV setting.
Objective We investigated the impact of cervical cell abnormalities detected in the puerperium in association with HIV-1 infection on pregnancy outcomes. Methods A behavioural intervention RCT enrolled 1480 pregnant ...
Transforming growth factor βeta 1-3 in HIV associated pre-eclampsia.
Introduction: Pre-eclampsia is a clinical syndrome that complicates approximately 3-8% of all pregnancies and is the second leading cause of maternal mortality. The maternal imbalance of pro-angiogenic and anti-angiogenic ...
Salivary gland tumours in the era of antiretroviral treatment.
HIV is a global pandemic with an estimated 36.7 million people infected worldwide with HIV in 2015. Sub Saharan Africa remains the region most heavily affected with South Africa being home to the world’s largest ...