• Evaluation of the potential benefits of L-ergothioneine on selected complications associated with type-2 diabetes in a rat model. 

  Dare, Ayobami. (2021)

  Several pathogenic factors promote type-2 diabetic complications in patients, including cardiomyopathy, nephropathy, and non-alcoholic fatty liver disease (NAFLD). Specific nutraceuticals from food may act as a medicinal ...

• Investigating the effects of diet-induced pre-diabetes on calcium homeostasis in male Sprague Dawley rats. 

  Naidoo, Karishma. (2022)

  Diabetes mellitus (DM) affects over 400 million people worldwide with 90-95% being type 2 diabetes mellitus (T2DM) in South Africa. T2DM is positively correlated with the chronic consumption of a high caloric diet, often ...

• The association between renal sonography and renal function in chronic kidney disease at Inkosi Albert Luthuli Chief Hospital: a retrospective descriptive study. 

  Frank, Astley Gershwyn. (2020)

  Background Non-communicable diseases (NCDs) are rapidly emerging as a major cause of chronic kidney disease (CKD) in Africa with a reported prevalence of 10.7% locally. At current, few high-quality studies assessing the ...

• Surgical outcomes of HIV seropositive adult patients with intracranial hypertension secondary to cryptococcal meningitis. 

  Mabovula, Ndyebo Samkelo. (2020)

  Overview available in PDF.

• The utility of PSA density and free PSA in the prostate biopsy decision-making process in a South African population. 

  Maher, Ashfaaq Abdullah. (2021)

  Background: Controversy around the role of PSA screening for prostate cancer still exists because evidence has not yet shown that it saves lives. Additional tests used in conjunction with PSA, can improve the sensitivity ...

• Tenofovir microbicide gel as an effective prophylactic measure to human herpes virus-8. 

  Bhorat, Raeesa Ismail. (2019)

  Background: High prevalence and incidence rates of human herpes virus-8 (HHV-8) contributes significantly in the aetiology of cancers, including Kaposi sarcoma (KS). These cancers remain among leading causes of morbidity ...

• A ten-year retrospective review of patients presenting to Inkosi Albert Luthuli Central Hospital with infective endocarditis with special reference to HIV positive patients. 

  Naidoo, Nerissa Sanrisha. (2021)

  Abstract available in PDF.

• Tenofovir microbicide gel as an effective prophylactic measure to human herpes virus-8. 

  Raeesa., Ismail Bhorat. (2019)

  Background: High prevalence and incidence rates of human herpes virus-8 (HHV-8) contributes significantly in the aetiology of cancers, including Kaposi sarcoma (KS). These cancers remain among leading causes of morbidity ...

• Local experience of patients with connective tissue associated interstitial lung disease who were treated with cyclophosphamide. 

  Singh, Swasti Gitesh. (2021)

  Introduction: Interstitial lung disease (ILD) is a major cause of death amongst individuals with connective tissue diseases (CTD). Although there is no cure for CTD-ILD the need to retard disease progression is vital, ...

• Outcomes of elective surgical patients admitted to a tertiary Paediatric Intensive Care Unit. 

  Ntombela, Zamaswazi Princess. (2021)

  Background: A paediatric intensive care unit (PICU) is a unit for critically ill medical and surgical children. It is imperative that the spectrum and outcome of elective surgical patients is reviewed to help develop ...

• Adequate analgesia in caring for paediatric burns patients in a peri-urban setting in KZN. 

  Wall, Shelley Lynn. (2020)

  This PhD thesis centres on achieving adequate analgesia in caring for paediatric burn-injured patients in KwaZulu-Natal, South Africa. The burden of burn injuries in sub-Saharan Africa is huge. A large number of children ...

• Epidemiology of chronic kidney disease in KwaZulu-Natal: evaluation of risk factors, complications and diagnostic methods. 

  Madala, Nomandla Daphne. (2017)

  Chronic kidney disease (CKD) is associated with increased morbidity and mortality as well as costly renal replacement therapy. The aim was to determine risk factors and complications that contribute to morbidity as ...

• Trauma care in Sub-Saharan Africa: challenges and opportunities in Botswana and Tanzania for implementing Afrocentric systems. 

  Mwandri, Michael Bartholomew. (2021)

  Summary available in PDF.

• Evidence on the surgical management of obstructive sleep apnoea in adults with focus on uvulopalatopharyngoplasty: a scoping review. 

  Makhaye, Winile Patricia. (2021)

  Background: Over the years, various treatment options have been recommended to patients to manage obstructive sleep apnoea (OSA). This study aims to systematically map recent evidence on surgical management of obstructive ...

• Observed birth prevalence of structural congenital disorders among live births at a regional facility in South Africa. 

  Saib, Muhammad Zubayr. (2021)

  Congenital disorders (CDs) are a global health issue and an important contributor to childhood mortality and morbidity. In South Africa (SA), the size and nature of the problem is unknown because reporting of CDs has been ...

• The impact of semen exposure on cytokine response and bacterial vaginosis in the female genital tract. 

  Mngomezulu, Khanyisile Happiness. (2018)

  Background: Diverse microbial communities and inflammatory cytokine responses in the lower female genital tract (FGT) are closely associated with increased human immunodeficiency virus (HIV-1) risk, possibly through ...

• Molecular surveillance of Staphylococcus aureus on frequently touched sites in public hospitals in KwaZulu-Natal, South Africa. 

  Mkhize, Siyethaba. (2021)

  There is an escalation in the prevalence of hospital-acquired infections (HAI) due to the transfer of pathogens, such as methicillin-resistant Staphylococcus aureus (MRSA), within the hospital environment. Pathogens ...

• Distribution, virulence and antimicrobial resistance profile of Bacillus species from the environment of four public hospitals in South Africa. 

  Mbhele, Zamile Nompumelelo. (2021)

  Hospital-acquired infections (HAIs) are counted as the most crucial global health crisis. The hospital environment may be colonized by opportunistic pathogens, which can lead to HAIs in hospitalized patients. As a result, ...

• The impact of semen exposure on the immune and microbial environments of the female genital tract. 

  Jewanraj, Janine. (2021)

  Background: Semen is an immunomodulatory fluid that induces mucosal changes at the female genital tract (FGT) for sperm survival and conception. Semen-induced alterations necessary for reproduction may also modulate the ...

• Molecular epidemiology of antibiotic-resistant Escherichia coli and Enterococcus spp. from agricultural soil fertilized with chicken litter in uMgungundlovu district, KwaZulu-Natal Province, South Africa. 

  Fatoba, Dorcas Oladayo. (2021)

  The application of animal manure contaminated with antibiotic-resistant bacteria (ARB) and antibiotic-resistance genes (ARGs) represents a major route by which antibiotic resistance is transmitted into the soil environment. ...

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