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The changes in immune cells concentration during the progression of pre-diabetes to type 2 diabetes in a diet-induced pre-diabetic rat model.
(2019)T2D has been discovered to be preceded by a long-lasting condition known as prediabetes. The primary cause of prediabetes and T2D has also been shown to be continuous consumption of unhealthy diets and living a sedentary ... -
Evaluation of the Alere Afinion™ AS100 for measuring the levels of C-Reactive Protein in an aged population.
(2020)Introduction The Alere Afinion™ AS100 analyser is a compact bench-top, multi-assay, point-of-care (POC) analyser that provides valuable near patient testing at the point of care. It utilises the latest technology to measure ... -
Genotyping of trichomonas vaginalis in antenatal women from eThekwini.
(2020)Trichomonas vaginalis is the causative agent of trichomoniasis. The genetic characterisation of T. vaginalis isolates reveals significant genetic diversity in this organism. Data on the prevalence of different genotypes ... -
The effects of rhoicissus tridentate dichloromethane extract and its bioactive compounds on uterotonic and glucose lowering activity in-vitro.
(2019)Poor myometrial contractility during labour is associated with an extended partuition process that can affect the neonate’s health status. Chronic use of conventional treatments for diabetes mellitus is sometimes associated ... -
The biological mechanisms associated with Depo-Provera and HIV-1 risk acquisition in women.
(2017)Thirty-six years after the first identification of AIDS, the spread of its aetiological agents continues unabated, human immunodeficiency virus 1 (HIV-1) in particular. About 40% of HIV-1 infections have been reported to ... -
Computational studies of mycobacterium tuberculosis L, d-transpeptidase2.
(2018)Tuberculosis (TB) is still one of the most highly elusive lethal transmittable diseases to eradicate and persist to be a major threat to public health due to emergence of drug resistance. Drug-resistant is steadily increasing ... -
Deoxynivalenol downregulates NRF2-induced cytoprotective response in human hepatocellular carcinoma (HepG2) cells.
(2017)Deoxynivalenol (DON) is a mycotoxin produced by Fusarium species that commonly infect agricultural foods. DON exhibits multiple toxic effects in both animals and humans, binding to the A site of the 28S ribosome and inhibits ... -
In silico studies on Zika NS3 helicase: bedrock for antiviral drug design.
(2017)Zika virus is a re-emerging infectious disease, which was declared to be a public health emergency of international concern due to its various reported complications ranging from microcephaly in newborn to Guillain-Barré ... -
Tissue distribution of an anti-TB drug, TBA-354 in rats via mass spectrometric investigations.
(2016)Tuberculosis (TB) (TB) is one of the most well-recognized ancient human diseases in the history of mankind and it remains the major cause of human death amongst the transmittable diseases despite the use of antitubercular ... -
A comparative chemistry of coa® herbal medicine and herbal extracts of Vernonia Amygdalina (Bitter leaf) and Persea Americana (Avocado).
(2018)The aim of this study is to investigate the phytochemical compounds present in standard COA®, dichloromethane (DCM), ethanol (EtOH), hexane (HEX), and ethyl acetate (EtOAc) , extracts of COA® compared to leaf extracts ... -
In vitro and in vivo evaluation of metal-chelating agents as novel metallo beta-lactamase inhibitors against carbapenem-resistant enterobacteriaceae.
(2018)Infectious diseases remain one of the leading causes of death worldwide, despite the discovery of new and improvements on existing antibiotics. Bacteria are constantly developing sophisticated mechanisms of resisting the ... -
Frequency and phenotype of Immune cell subsets in different regions of the human cervix : implications for HIV susceptibility.
(2018)Abstract available in PDF file. -
Evaluation of the left ventricular ejection fraction post right ventricular pacing at Inkosi Albert Luthuli Central Hospital (IALCH), Durban, KwaZulu-Natal (KZN).
(2016)Since the implantation of the first artificial pacemaker in 1958, these devices have become the treatment of choice in bradycardias. Despite its widespread use, only a few studies have looked at the effects of single chamber ... -
Extrapulmonary tuberculosis at King Edward hospital : a descriptive retrospective study.
(2016)Background Globally, South Africa remains one of the top twenty high tuberculosis(TB) burden countries. In addition, South Africa has the highest burden of tuberculosis/Human Immunodeficiency virus (TB/HIV) coinfection in ... -
Defining current facial fracture patterns in a quaternary institution following high-velocity blunt trauma.
(2016)Background: In the early 20th century, René Le Fort studied facial fractures resulting from blunt trauma and devised a classification system still in common use today. This classification, however, was based on low-velocity ... -
Benign uterine conditions : correlating MRI and US findings : retrospective analysis of 33 patients.
(2016)Abstract not available. -
Case series of subtotal exenteration with buccal mucosal graft for orbital squamous cell carcinoma.
(2016)The aim of the study was to look for a safe alternative to a disfiguring total orbital exenteration for orbital squamous cell carcinoma, so that a standard hospital issue inexpensive stock ocular prosthesis can be fitted ... -
Seroprevalence and viral quantification of Kaposi Sarcoma-associated Herpes Virus (KSHV) in a Human Immunodeficiency Virus (HIV) infected adult South African cohort.
(2017)Background Kaposi sarcoma-associated herpes virus (KSHV), also known as human herpes virus 8 (HHV8), is aetiologically implicated in Kaposi’s sarcoma (KS). Although HIV associated KS has increased in incidence and is a ... -
A retrospective analysis of induction of labour at a regional hospital in KwaZulu-Natal, South Africa.
(2012)Abstract available in PDF file. -
Identification of anti-cancer agents using integrated computational tools.
(2015)Cancer is a heterogeneous disease that is responsible for various molecular changes and pathological entities that play vital roles in its response to treatment, survival, and growth. Better understanding into the critical ...
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