Mulholland, Dulcie Aca.Naidoo, Dashnie.2011-11-242011-11-2420012001http://hdl.handle.net/10413/4433Thesis (M.Sc.)-University of Natal, Durban, 2001.This work is an account of the extractives from one member of the Meliaceae and one member of the Ptaeroxylaceae. In all, thirteen compounds have been isolated, of which four have not been described previously. Neobeguea mahafalensis belongs to the Neobeguea genus and has been classified into the Swietenieae subfamily of the Meliaceae. Neobeguea mahafalensis seeds obtained from Madagascar were investigated for the presence of limonoids. This is the first time extracts of the seeds were investigated. Previous work was done on the stem bark of this species. An andirobin-type limonoid, methyl angolensate (5), two mexicanolide-type limonoids, mexicanolide (6), khayasin (7), and three protolimonoids, sapelin E acetate (8), sapelin C (9) and grandifoliolenone (10), have been isolated in this work. One of these was novel. Cedrelopsis grevei belongs to the Cedrelopsis genus and has been classified into the Ptaeroxylaceae family. Extracts from the stem bark of Cedrelopsis grevei obtained from Madagascar yielded seven compounds, a triterpenoid, β-amyrin (15), a coumarin, scoparone (16), a limonoid, cedmiline (14), a triterpenoid derivative, cedashnine (17), a quassinoid, cedphiline (19), a lignan, cedpetine (18) as well as sitosteryl β-D-glucopyranoside (20). Three of these were novel.enMeliaceae.Ptaeroxylaceae.Plants--Analysis.Limonoids.Theses--Chemistry.Thesis