Epigenetic mechanisms, T-cell activation, and CCR5 genetics interact to regulate T-cell expression of CCR5, the major HIV-1 coreceptor.

Gornalusse, German G.Mummidi, Srinivas.Gaitan, Alvaro A.Jimenez, Fabio.Ramsuran, Veron.Picton, Anabela.Rogers, Kristen.Manoharan, Muthu Saravanan.Avadhanam, Nymisha.Murthy, Krishna K.Martinez, Hernan.Murillo, Angela Molano.Chykarenko, Zoya A.Hutt, Richard.Daskalakis, Demetre.Shostakovich-Koretskaya, Ludmila.Abdool Karim, Salim Safurdeen.Martin, Jeffrey N.Deeks, Steven G.Hecht, Frederick M.Sinclair, Elizabeth.Clark, Robert A.Okulicz, Jason.Valentine, Fred T.Martinson, Neil.Tiemessen, Caroline Tanya.Ndung'u, Peter Thumbi.Hunt, Peter W.He, Weijing.Ahuja, Sunil K.2016-11-122016-11-1220152015Gornalusse, G.G., Mummidi, S., Gaitan, A.A., Jimenez, F., Ramsuran, V., Picton, A., Rogers, K., Manoharan, M.S., Avadhanam, N., Murthy, K.K., Martinez, H., Murillo, A.M., Chykarenko, Z.A., Hutt, R., Daskalakis, D., Shostakovich-Koretskaya, L., Abdool Karim, S.S., Martin, J.N., Deeks, S.G., Hecht, F., Sinclair, E., Clark, R.A., Okulicz, J., Valentine, F.T., Martinson, N., Tiemessen, C.T., Ndung’u, T., Hunt, P.W., He, W., and Ahuja, S.K. 2015. Epigenetic mechanisms, T-cell activation, and CCR5 genetics interact to regulate T-cell expression of CCR5, the major HIV-1 coreceptor. Proceedings of the National Academy of Sciences 112(34), E4762-E4771.http://dx.doi.org/10.1073/pnas.1423228112http://hdl.handle.net/10413/13680CAPRISA, 2015.Abstract available in pdf.enCCR5.HIV.T cell activation.Methylation.Polymorphism.Epigenetic mechanisms, T-cell activation, and CCR5 genetics interact to regulate T-cell expression of CCR5, the major HIV-1 coreceptor.Peer reviewed journal article