Padian, Nancy S.McCoy, Sandra I.Abdool Karim, Salim Safurdeen.Hasen, Nina.Kim, Julia.Bartos, Michael.Katabira, Elly.Bertozzi, Stefano M.Schwartlander, Bernhard.Cohen, Myron S.2013-08-022013-08-0220112011Published in final edited form as: Padian, N.S., et al. 2011. HIV prevention transformed: the new prevention research agenda. Lancet. 378 (9787) pp. 269–278.0140-6736http://dx.doi.org/10.1016/S0140-6736(11)60877-5http://hdl.handle.net/10413/9392We have entered a new era in HIV prevention whereby priorities have expanded from biomedical discovery to include implementation, effectiveness, and the effect of combination prevention at the population level. However, gaps in knowledge and implementation challenges remain. In this Review we analyse trends in the rapidly changing landscape of HIV prevention, and chart a new path for HIV prevention research that focuses on the implementation of effective and efficient combination prevention strategies to turn the tide on the HIV pandemic.enHIV infections--Prevention.HIV infections--Testing.Voluntary medical male circumcision (VMMC)Prevention of mother to child transmission (PMTCT)Peer reviewed journal article