Cooperation between strain-specific and broadly neutralizing responses limited viral escape and prolonged the exposure of the broadly neutralizing epitope.

Anthony, Colin S.York, Talita.Bekker, Valerie.Matten, David.Selhorst, Philippe.Ferreria, Roux-Cil.Garrett, Nigel Joel.Abdool Karim, Salim Safurdeen.Morris, Lynn.Wood, Natasha T.Moore, Penelope L.Williamson, Carolyn.2018-03-132018-03-1320172017Anthony, C., York, T., Bekker, V., Matten, D., Selhorst, P., Ferreria, R.C., Garrett, N.J., Abdool Karim, S.S., Morris, L., Wood, N.T., Moore, P.L. and Williamson C. 2017. Cooperation between strain-specific and broadly neutralizing responses limited viral escape and prolonged the exposure of the broadly neutralizing epitope. Journal of virology 91(18), e00828-17.http://hdl.handle.net/10413/15075CAPRISA, 2017.Abstract available in pdf.enN332 glycan.V3-glycan supersite.Broadly neutralizing antibodies.Deep sequencing.Glycan holes.Glycan shield.Helper/cooperating NAb responses.Neutralization escape.Viral escape.Cooperation between strain-specific and broadly neutralizing responses limited viral escape and prolonged the exposure of the broadly neutralizing epitope.Peer reviewed journal article