Singh, Jerome Amir.Abdool Karim, Salim Safurdeen.Abdool Karim, Quarraisha.Mlisana, Koleka Patience.Williamson, Carolyn.Gray, Clive M.Govender, Michele.Gray, Andrew Lofts.2012-11-262012-11-2620062006Singh, J.A. et al. 2006. Enrolling adolescents in research on HIV and other sensitive issues: lessons from South Africa. PLoS Med 3(7): e180. DOI: 10.1371/journal.pmed.00301801549-1277http://dx.doi.org/10.1371/journal.pmed.0030180http://hdl.handle.net/10413/8013The article discusses the challenge of enrolling adolescents in HIV studies in South Africa. It is practically impossible in some instances to seek parental consent or to determine who, if anyone, is the legal guardian to authorize an adolescent's participation in research. The South African Medical Research Council research ethics guidelines prescribe 14 years of age as the autonomous age of consent for therapeutic research but not observational studies.enTeenagers--Health and hygiene.HIV infections.Consent (Law)Medicine--Research.Research--Moral and ethical aspects.Peer reviewed journal article