Kruger, Hendrik Gerhardus.Maguire, Glenn Eamonn Mitchel.Lin, Johnson.Maseko, Sibusiso Bonginkosi.2020-04-152020-04-1520182018https://researchspace.ukzn.ac.za/handle/10413/17990Doctoral Degree. University of KwaZulu-Natal, Durban.Abstract available in pdf.enResistant HIV-PROTEASE (C-SA) mutants.HIV-1 resistance.HIV-1 protease.Protease inhibitors.Mutations in the protease molecule.Mutants.HIV-1 C-SA (South African subtype C).Molecular analysis of HIV-1 resistance: biosynthesis, kinetic, and thermodynamic study of resistant HIV-PROTEASE (C-SA) mutants.Thesis