Background: A number of Mycobacterium tuberculosis (Mtb) genes have been shown to be under positive selection pressure in the presence of anti-TB therapy. This results in the selection of drug resistant phenotypes associated ...

Tuberculosis is one of the most deadly infectious diseases currently plaguing the global community. Unfortunately, lack of accessible, reliable and affordable diagnostic tools in the high disease burden, and resource poor ...

Background: Global incidence rates for tuberculosis (TB) indicate a gender-bias to the disease, with almost twice as many men actively infected than women (male/female ratio of 1.9). Sex hormones are known to regulate immune ...

In the same way that the HIV virus subdues the human immune system, the HIV/AIDS epidemic has severely overloaded the health service infrastructure in resource limited countries and threatens to systematically suppress ...

HIV-1 RNA assays are routinely used in developed countries to monitor the effectiveness of antiretroviral therapy (ART). These assays require well-trained operators, expensive equipment and reagents, and established ...

Drug resistant tuberculosis is a major contributor to South Africa’s quadruple burden of disease. Management of this infection in a highly HIV endemic area is a constant challenge. There is a paucity of new anti-tuberculosis ...

This study was conducted to establish the scientific basis of the reported ethnomedicinal use of Ihlamvu laseAfrika (IHL) against Human Immunodeficiency Virus (HIV) and Acquired Immunodeficiency Virus (AIDS) related ...

Although Mycobacterium tuberculosis, the causative agent of tuberculosis (TB), is now considered a facultative anaerobe, and bacilli isolated from sputum specimen possess morphologies identified from bacilli growing ...