Now showing items 1-5 of 5
The effects of Sutherlandia frutescens and Fumonisin B1 on Jurkat cells.
The medicinal plant Sutherlandia frutescens (SF) is commonly consumed in South Africa, and is traditionally applied to a range of ailments. Yet its popularity stems from the use of SF as a cancer treatment. This plant ...
Killing of mycobacteria by macrophage cathepsin D.
Tuberculosis (TB) is the fifth largest cause of death in South Africa, with one in ten cases being resistant to treatment due to the development of multidrug-resistance and extensively drug-resistance in the agent responsible ...
Fructose-fed streptozotocin-injected rat : an alternative model for type 2 diabetes.
The principal objective of this study was to develop an alternative non-genetic rat model for type 2 diabetes (T2D). Six-week-old male Sprague-Dawley rats (190.56 ± 23.60g) were randomly divided into six groups namely: ...
Enzymatic and crystallisation studies of CATL-like trypanosomal cysteine peptidases.
African animal trypanosomosis or nagana is a disease in livestock caused by various species of protozoan parasites belonging to the genus Trypanosoma particularly T. congolense, T. vivax and T. b. brucei. Nagana is the ...
p38 MAPK and the C2C12 cell cycle : in vitro and in silico investigations.
The mammalian cell cycle and its points-of-entry are well characterized pathways. These points-of-entry are normally regulated via mitogens and include, amongst others, the ERK, JNK and p38 mitogen-activated protein ...