Browsing Masters Degrees (Biochemistry) by Title
Now showing items 10-29 of 125
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Bio-guided isolation of biologically active compounds from seeds of selected South African medicinal plants.
(2016)Abstract available in PDF file. -
Biochemical and microbiological changes in sugarcane stalks during a simulated harvest-to-crush delay.
(2008)Post-harvest cane deterioration in the South African sugar industry results in significant revenue loss that is estimated to be in the region of ZAR 60 million per annum. Despite these large losses, precise biological ... -
The biochemical effects of Sutherlandia Frutescens in cultured H9 cancerous T cells and normal human T lymphocytes.
(2008)Indigenous plants have long been used by African populations in their cultural lives and health care. Sutherlandia frutescens (SF) is a popular traditional medicinal plant found in various parts of southern Africa and used ... -
Biochemical studies on trypanosomal prolyl oligopeptidase family pathogenic factors.
(2014)African Animal trypanosomosis, also known as Nagana, is a parasitic disease which affects many mammalian species, mainly livestock such as cattle, sheep and goats. The disease also affects humans (Human African Trypanosomosis) ... -
Bioremediation of soil contaminated with a mixture of chlorinated aliphatic hydrocarbons.
(2008)Chlorinated aliphatic hydrocarbons (CAH’s) are a diverse group of industrial chemicals that play a significant role as pollutants of soil and groundwater. They are recalcitrant and resist degradation in most waste treatment ... -
Biotyping of clinical mycobacterium tuberculosis isolates using MALDI-TOF MS.
(2013)Tuberculosis continues to be a major threat in public health; 8.8 million incidence of TB has been reported and 2 million deaths every year. Diagnosis of TB is impeded by slow growth of an organism with a generation time ... -
Canine anti-endotoxin immunotherapy in cranial mesenteric arterial occlusion shock and canine parvovirus disease endotoxaemia.
(1986)Endotoxin (LPS, lipopolysaccharide) forms an integral part of the outer cellular membrane of gram negative bacteria (GNB). The canines' intestine always contains large amounts of GNB, and hence LPS. If these GNB with ... -
Cationic liposome mediated targeted gene delivery with and without pegylated accessories.
(2009)As a consequence of safety issues encountered by the use of viral vectors in gene therapy, there has been a steady increase in the development and application of non-viral vectors, especially liposomes. Cationic liposome ... -
Characterization of the immunity factor in producer self protection against Leucocin A.
(2008)Lactic acid bacteria produce pediocin-like bacteriocins designated as Class Ha. These antimicrobial peptides are antagonistic against Listeria monocytogenes and other closely related Gram-positive bacteria Self-protection ... -
Characterization of the insulin signalling pathways in skeletal muscle and skin of streptozotocin-induced diabetic male Sprague-Dawley rats : the effects of oleanolic acid.
(2013)Treatment of diabetes mellitus is mainly focused on glycaemic control regulated by insulin and takes place in insulin sensitive tissues like skeletal muscle which accounts for 75% of glucose metabolism. Plant derived ... -
Cloning and recombinant expression of a 822 bp region of a Pf403 Plasmodium falciparum gene.
(2003)Malaria is a devastating parasitic disease in humans caused by species in the genus Plasmodium. With over 100 million cases and at least 1.5 million fatalities each year, the disease accounts for 4-5% of all fatalities ... -
Cloning of the promoter regions of Trypanosoma brucei and Trypanosoma congolense cysteine protease genes.
(1997)Trypanosoma brucei and T. congolense are protozoan parasites that infect humans, domestic livestock and wildlife in Africa. These parasites undergo complex morphological and biochemical changes, during the various stages ... -
The comparative effects of acetylated and deacetylated galactose derivatives in liposomal gene delivery.
(2014)The use of cationic liposomes remains the most attractive non-viral approach in gene therapy as these gene carriers provide for ease and versatility in design. In targeted gene delivery, liposomes are coupled to ligands ... -
A comparative study on three unique galactosylated cationic liposomes with their steically stablized counterparts, in HepG2 cells.
(2013)Receptor mediated endocytosis allows for the site specific delivery of exogenous DNA via appropriate ligand-receptor interactions. Various ligands have been used to target the asialoglycoprotein receptor (ASGP-R) present ... -
Constitutive over-expression of FL01 encoded mannoproteins.
(2014)The ability of yeast cell wall-derived mannoproteins (glycoproteins) to positively contribute to oenological properties has been a key factor that stimulates research initiatives into these industrially important glycoproteins. ... -
Coupling dyes to chicken IgY antibodies for the development of immunodiagnostic tests.
(2003)The aim of this study was to develop a highly simplified, sensitive and specific malarial diagnostic test at the lowest possible cost. Initial work and optimisation of procedures was achieved with chicken antibodies by ... -
A critical analysis of research done to identify conceptual difficulties in acid-base chemistry.
(2009)The literature review shows that student alternative conceptions or misconceptions are important for teaching and learning. Causes of such student difficulties may include the counter-intuitive nature of some chemistry ... -
Delivery of Fluc-mRNA using functionalised gold nanoparticles in vitro.
(2016)Nanomedicine, a branch of nanotechnology which includes the use of nanoparticles, is set to revolutionize the area of gene therapy. Gold nanoparticles (AuNPs) have steadily gained favour as promising gene and drug delivery ... -
The detection of two plasmodium falciparum metabolic enzymes using chicken antibodies.
(2012)Three protein targets are used in malaria rapid diagnostic tests (RDTs). These are Plasmodium falciparum histidine rich protein 2, Plasmodium lactate dehydrogenase and aldolase. A thrust of research in RDTs is to improve ... -
Development of a novel biochemical assay for the identification of promiscuous compounds.
(2019)Promiscuous compounds, specifically aggregate-based inhibitors that result in false positives in biochemical activity assays present a serious and increasing interference to early-stage drug discovery processes. Although ...