Browsing Masters Degrees (Biochemistry) by Title
Now showing items 106-123 of 123
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Silver nanoparticles from biological extracts and their antimicrobial activities.
(2017)The increasing incidence of multi-drug resistant organisms has led to the resurgence in application of Ag-based compounds. Accordingly, increased efforts have been made in the field of nanotechnology to develop silver ... -
The stabilisation of the cysteine protease of Carica papaya (papain) and the catalytic domain of the Cathepsin L-like cysteine protease of Trypanosoma congolense (TcoCATL)
(2019)Proteases play an intricate role in the numerous functions of a living organism. Proteases are responsible for the cleavage of proteins into smaller fragments by catalysing the hydrolysis of peptide bonds. The class of ... -
Structural studies aimed at improving the antigenicity of congopain.
(2009)African animal trypanosomosis or nagana is a tsetse fly-transmitted disease, caused by Trypanosoma congolense, T. vivax and to a lesser extent T. brucei brucei. The disease causes major losses in revenue in many ... -
Students' use of diagrams for the visualisation of biochemical processes.
(2003)Research into the usefulness of scientific diagrams as teaching and learning tools has revealed their great effectiveness in reinforcing and replacing text; summarizing, clarifying, grouping and comparing information; ... -
Studies on the possible mechanisms behind the anti-diabetic effects of Xylitol.
(2013)Background and Objectives: Sugar substitutes have gained popularity in the management of diabetes, obesity and related diseases, due to their low calorie content compared to sucrose. Recent studies have reported that ... -
Studies on the preparation and interaction of modified transferrin-DNA complexes with HeLa cells.
(1986)The correction of human genetic disorders by transfer of genetic material to cells is under intensive investigation in a number of 1aboratories. One possible way of trying to achieve the transfer of nucleic acid is ... -
A study of recombinant Plasmodium falciparum PFC0760c.
(2011)Malaria is a devastating disease caused by one of the world's most pathogenic parasites, Plasmodium. Five species of Plasmodium infect humans: P. falciparum, P. vivax, P. ovale, P. malariae and P. knowlesi. P. falciparum ... -
The study of the impact of selected mutations in FMS-like Tyrosine Kinase III (FLT3) and Nucleophosmin (NPM1) - and HIV status on patients with acute Myeloid Leukemia and their response to induction therapy.
(2012)Acute Myeloid Leukemia (AML), the most common form of acute leukemia in adults, is only curable in approximately 30% of all cases. Despite prognostic risk stratification using sub-typing and cytogenetic analysis to direct ... -
Studying trypanosomal peptidase antigen targets for the diagnosis of animal African trypanosomiasis.
(2013)The lack of a vaccine candidate due to antigenic variation by trypanosomal parasites, the causative agents of human and animal African trypanosomiasis, requires the disease to be controlled by surveillance, diagnosis and ... -
Synthesis of DNA - protein conjugates and a preliminary study of their interaction with eukaryotic cell receptors.
(1986)Thymidine oligomers were chemically synthesised and linked to available amino functions of transferrin in alternative orientations: (a) A CMP residue attached to the 3' end of (pT)₁₀ with terminal deoxynucleotidyl transferase ... -
Synthesis, cloning and expression of an antifungal peptide, ESF1, in saccharomyces cerevisiae.
(2000)ESF1 is a 2.052 kDa antimicrobial peptide, mimicking the charge distribution and amphipathic alpha-helical structure of magainin, pGLa, a naturally occurring antimicrobial peptide. ESF1 has been reported to display high ... -
Transferrin receptor-mediated gene delivery using functionalised gold nanoparticles.
(2018)Gene therapy strategies have shown their potential in treating numerous central nervous system (CNS) disorders, including highly aggressive brain cancers. Gold nanoparticles (AuNPs) are popular vectors for gene delivery, ... -
Trypanosoma congolense invariant surface glycoprotein: a potential diagnostic antigen for animal African trypanosomiasis.
(2016)Abstract available in PDF file. -
The use of cholesterol-galacto compounds in liver directed gene delivery.
(2014)Gene therapy has to date gained immense interest as a potential method for treating genetic disorders such as Parkinson’s and cystic fibrosis. The liver being a central organ of metabolism is susceptible to several ... -
Vivapain : a cysteine peptidase from Trypanosoma vivax.
(2010)African animal trypanosomosis is a devastating disease affecting livestock mainly found in sub-Saharan Africa. This disease is known as nagana and is transmitted by the trypanosome parasite from the tsetse fly vector to a ... -
VP4 : a putative protease encoded by infectious bursal disease virus.
(2000)Infectious bursal disease virus (IBDV) causes an acute and highly contagious disease affecting young chickens, which is responsible for significant losses in the poultry industry world-wide. The virus specifically infects ... -
Yeast encapsulation for bioethanol production.
(2014)The bioethanol production industry is faced with hurdles such as uncovering cheap and abundantly available fermentation substrates, as well as yeast strains possessing high ethanol tolerance properties. Cane molasses is a ...