Browsing Masters Degrees (Biochemistry) by Title
Now showing items 84-103 of 123
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Nickel accumulation and tolerance in Berkheya coddii and its application in phytoremediation.
(1998)As pollution becomes an ever-increasing threat to the global environment pressure is being placed upon industry to "clean-up" its act, both in terms of reducing the possibility of new pollution and cleaning up already ... -
A novel in vitro anticancer drug delivery strategy using platinum encapsulated gold nanoparticles.
(2017)Abstract available in PDF file. -
Over-expression of FLO genes in Saccharomyces cerevisiae BY4742 strains bearing a deletion in genes related to cell wall biogenesis.
(2013)Mannoproteins form the outermost layer of the cell wall in Saccharomyces cerevisiae. These glycoproteins are first synthesized in the endoplasmic reticulum and undergo posttranslational modification before they are transported ... -
Over-expression of FLO11 encoded mannoprotein in Saccharomyces cerevisiae.
(2015)Abstract available in PDF file. -
p38 MAPK and the C2C12 cell cycle : in vitro and in silico investigations.
(2011)The mammalian cell cycle and its points-of-entry are well characterized pathways. These points-of-entry are normally regulated via mitogens and include, amongst others, the ERK, JNK and p38 mitogen-activated protein ... -
Phytochemistry and anti-cancer potential of compounds isolated from Kenyan medicinal plants, Moringa oleifera and Prunus africana.
(2014)Cancer is one of the leading causes of death worldwide and of all the cancer related deaths occurring worldwide, 70% are in low and middle income countries. In Africa, the disease kills more people than HIV, TB and malaria ... -
Preparation of chemically modified transferrin proteins and an investigation of their reactions with DNA and other nucleic acids.
(1986)The molecular biology of human genetic disorders is under intensive investigation at present. In those cases where the disorder is clearly defined in terms of altered gene structure, possibilities may exist for the correction ... -
Prevalence of molecular markers associated with chloroquine, sulphadoxine-pyrimethamine and lumefantrine resistance following the deployment of artemether-lumefantrine as first-line treatment for uncomplicated falciparum malaria in Gaza Province, Mozambique.
Antimalarial drug resistance is a major contributing factor to the sustained malaria burden in sub-Saharan Africa. Under extreme drug pressure, drug resistant parasites have a selective fitness advantage over wild-type ... -
Protease distribution in J774 macrophages
(2007)Cathepsin, matrix metalloproteinase (MMP) enzyme and tissue inhibitor of MMP (TIMP) distribution in J774 mouse macrophages has not been comprehensively studied. The distribution and vesicle regulation, trafficking and ... -
Protein expressions of Acinetobacter sp. isolates LT1A and V2 during hydrocarbon degradation.
(2012)Bacteria of the genus Acinetobacter are known to be involved in the degradation, leaching and removal of various hazardous compounds from the environment. Several studies of Acinetobacter spp. have reported on the genes ... -
Real-time quantitative PCR analysis of diesel-degrading genes of acinetobacter calcoaceticus isolates.
(2009)The diesel-degrading capabilities of Acinetobacter calcoaceticus isolates LT1, LT1A and V2 were established in previous studies. LT1 and LT1A were isolated from diesel-contaminated soil and V2 was from soil contaminated ... -
Recombinant expression and bioinformatic analysis of plasmodium falciparum lactate dehydrogenase and heat shock protein 70-1.
(2017)Malaria remains a serious human health problem and the disease is particularly prevalent in developing countries. Malaria is caused by a parasite of the genus Plasmodium. Diagnosis of malaria is required before any treatment ... -
Recombinant expression and evaluation of a- and b- tubulin from Trypanosoma congolense as vaccine candidates for African trypanosomiasis.
(2010)African trypanosomiasis is caused by protozoan parasites known as trypanosomes, which are transmitted by the tsetse fly, affecting both humans and animals. Trypanosoma congolense is one of the main trypanosome species ... -
Recombinant expression and initial characterisation of two Plasmodium falciparum copper binding proteins: Cox11 and Cox19.
(2018)Emerging drug resistance hinders the efforts to control malaria and so novel antimalarial drugs are required. Copper is essential for the survival of plasmodial parasites but the proteins involved in copper homeostasis are ... -
Recombinant expression of, and characterisation of antibodies against variable surface glycoproteins : LiTat 1.3 and LiTat 1.5 of Trypanosoma brucei gambiense.
(2013)Human African Trypanosomiasis (HAT), also known as sleeping sickness is one of the many life threatening tropical diseases posing a serious risk to livelihoods in Africa. The disease is restricted to the rural poor across ... -
Recombinant expression optimisation and characterisation of peptidases for diagnosis of animal African Trypanosomosis.
(2018)Abstract available in PDF file. -
Recombinant expression, purification and characterisation of TviCATL for antibody production and diagnosis of African animal Trypanosomiasis.
(2014)For the effective control of African animal trypanosomiasis, there is a great need for the development of point of care diagnostic tests that are affordable to the end-users. Parasite cysteine proteases are involved in the ... -
Recombinant expression, purification, analysis and immunization of mice with plasmodium yoelii glyceraldehyde-3-phosphate dehydrogenase (rPyGAPDH) and lactate dehydrogenase (rPyLDH) and evaluation of protection against P. berghei challenge.
(2019)The principal focus in malaria research is the development of an effective malaria vaccine which will help to prevent death and eliminate the disease. This study investigated two plasmodial glycolytic enzymes as possible ...