Browsing Masters Degrees (Biochemistry) by Title
Now showing items 70-89 of 115
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Killing of mycobacteria by macrophage cathepsin D.
(2011)Tuberculosis (TB) is the fifth largest cause of death in South Africa, with one in ten cases being resistant to treatment due to the development of multidrug-resistance and extensively drug-resistance in the agent responsible ... -
Location and partial purification of phosphate dependent glutaminase from rat small intestine.
(2014)Phosphate dependent glutaminase (PDG) is a key enzyme in intestinal energy metabolism and hence has an impact on nutrient absorption and nutritional status of the whole animal. PDG is known to be a mitochondrial enzyme but ... -
The measurement of glomerular basement membrane components and glycated albumin as improved markers of incipient diabetic nephropathy.
(2010)Diabetes causes early structural changes to the glomerular basement membrane (GBM), which alters its function and leads to loss of protein in urine. Formation of advanced glycation endproducts (AGEs) is one mechanism ... -
Membrane permeability of HIV-1 protease inhibitors.
(2014)According to the 2012 UNAIDS global report, sub-Saharan Africa hosts 69% of the world’s total population living with HIV, South Africa being the most affected with a reported 24% incidence rate. To date, extensive research ... -
Membrane type I metalloproteinase (mt1-mmp) as a target in cancer : a study of two inhibitors.
(2013)Several diseases, including cancer, have been associated with high membrane type-1 matrix metalloproteinase (MT1-MMP) expression levels. MT1-MMP together with a non-membrane-bound, soluble MMP, MMP-2, also associated with ... -
Membrane type-1 matrix metalloproteinase (MT1-MMP) as a target in cancer therapy.
(2007)Membrane type I-matrix metalloproteinase (MT1-MMP), a member of the highly active extracellular matrix (ECM)-degrading matrix metalloproteinases (MMPs), is known to be involved in connective tissue remodelling and ... -
Methods for serological and PCR detection of Salmonella enteritidis in chickens.
(2003)Salmonella enteritidis (S. enteritidis) is a bacterial pathogen of chickens, and is currently one of the leading causes of human food poisoning in the world. It is believed that contaminated poultry products, especially ... -
Methods for serotype classification of Haemophilus paragallinarum field isolates.
(1998)Historically, the causative agent of infectious coryza has been identified as the NAD requiring bacterium Haemophilus paragallinarum and the implementation of an intensive vaccination program led to the effective control ... -
Microbial and physico-chemical quality of some surface water resources in Durban, South Africa.
(2010)Microbial and chemical contamination of inland and coastal waters in Southern Africa is a major challenge facing the water industry and regulatory authorities. Increased stresses on these surface water resources through ... -
Microbiology honours students' conceptual development during a beer brewing teaching learning sequence (TLS)
(2010)Brewing is defined as “the combined processes of preparing beverages from the infusion of sound grains that have undergone sprouting, and the subsequent fermentation of the sugary solution produced, by yeast-whereby a ... -
Molecular analysis of the congopain gene family.
(2008)Animal trypanosomosis is a major constraint in livestock production in Sub-Saharan Africa. With the emergence of resistance against trypanocidal drugs, the cost and environmental concerns raised by vector control, and the ... -
Nickel accumulation and tolerance in Berkheya coddii and its application in phytoremediation.
(1998)As pollution becomes an ever-increasing threat to the global environment pressure is being placed upon industry to "clean-up" its act, both in terms of reducing the possibility of new pollution and cleaning up already ... -
A novel in vitro anticancer drug delivery strategy using platinum encapsulated gold nanoparticles.
(2017)Abstract available in PDF file. -
Over-expression of FLO genes in Saccharomyces cerevisiae BY4742 strains bearing a deletion in genes related to cell wall biogenesis.
(2013)Mannoproteins form the outermost layer of the cell wall in Saccharomyces cerevisiae. These glycoproteins are first synthesized in the endoplasmic reticulum and undergo posttranslational modification before they are transported ... -
Over-expression of FLO11 encoded mannoprotein in Saccharomyces cerevisiae.
(2015)Abstract available in PDF file. -
p38 MAPK and the C2C12 cell cycle : in vitro and in silico investigations.
(2011)The mammalian cell cycle and its points-of-entry are well characterized pathways. These points-of-entry are normally regulated via mitogens and include, amongst others, the ERK, JNK and p38 mitogen-activated protein ... -
Phytochemistry and anti-cancer potential of compounds isolated from Kenyan medicinal plants, Moringa oleifera and Prunus africana.
(2014)Cancer is one of the leading causes of death worldwide and of all the cancer related deaths occurring worldwide, 70% are in low and middle income countries. In Africa, the disease kills more people than HIV, TB and malaria ... -
Preparation of chemically modified transferrin proteins and an investigation of their reactions with DNA and other nucleic acids.
(1986)The molecular biology of human genetic disorders is under intensive investigation at present. In those cases where the disorder is clearly defined in terms of altered gene structure, possibilities may exist for the correction ... -
Prevalence of molecular markers associated with chloroquine, sulphadoxine-pyrimethamine and lumefantrine resistance following the deployment of artemether-lumefantrine as first-line treatment for uncomplicated falciparum malaria in Gaza Province, Mozambique.
Antimalarial drug resistance is a major contributing factor to the sustained malaria burden in sub-Saharan Africa. Under extreme drug pressure, drug resistant parasites have a selective fitness advantage over wild-type ...